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| EDITORIALS |
| 694 | Minimize systemic oral corticosteroids use and reduce harm for patients with asthma
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| 696 | Mepolizumab attenuates ILC2s proliferation and activity in adults with severe eosinophilic asthma
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| 699 | Unveiling the importance of evaluating the nutritional status in idiopathic pulmonary fibrosis patients with antifibrotic agent introduction
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| 701 | Ketogenic diets for obesity-hypoventilation syndrome? Interesting physiology but a long way to go
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| COMMENTARIES |
| 703 | Diverse e-cigarette regulations in the Asia Pacific: A health economic perspective
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| 706 | Respiratory and population effects of e-cigarettes: A Chinese perspective
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| INVITED REVIEW SERIES |
| The Future of Asthma |
| 709 | Biologics for severe asthma—Which, when and why?
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| POSITION PAPER |
| 722 | Proposed quality indicators and recommended standard reporting items in performance of EBUS bronchoscopy: An official World Association for Bronchology and Interventional Pulmonology Expert Panel consensus statement
Daniel P Steinfort, Matthew Evison, Ashleigh Witt, Georgios Tsaknis, Fayez Kheir, David Manners, Karan Madan, Calvin Sidhu, Alberto Fantin, Daniel A Korevaar, Erik H F M Van Der Heijden, on behalf of the WABIP Taskforce on Quality Indicators in EBUS Bronchoscopy
10.1111/resp.14549 |
| REVIEW |
| 744 | The burden of systemic corticosteroid use in asthma management in Asia
Raja Dhar, Chin Kook Rhee, Diahn-Warng Perng, Koichi Fukunaga, Mary Sau-Man Ip, Siwasak Juthong, Mariko Siyue Koh, Jing Li, Shubham Sharma, Wiwien Heru Wiyono
10.1111/resp.14533
See related editorial |
| ORIGINAL ARTICLES |
| Asthma and Allergy |
| 758 |
Severe asthma ILC2s demonstrate enhanced proliferation that is modified by biologics
Bilal Malik, Nathan W Bartlett, John W Upham, Kristy S Nichol, John Harrington, Peter A B Wark
10.1111/resp.14506
Type 2 innate lymphoid cells (ILC2) from severe eosinophilic asthma subjects demonstrate increased proliferation and type 2 cytokine secretion that was reduced by mepolizumab, and to a lesser extent by omalizumab.
See related editorial |
| COPD |
| 767 | Ηeparan sulphate in infectious and non-infectious exacerbations of COPD
Eleni Papakonstantinou, Maria-Elpida Christopoulou, Meropi Karakioulaki, Leticia Grize, Michael Tamm, Daiana Stolz
10.1111/resp.14531
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with worsening health outcomes and effective treatment of each episode is essential. Circulating levels of heparan sulphate (HS) are increased at AECOPD and this increase may be associated with the aetiology of these events. |
| Interstitial Lung Disease |
| 775 | Geriatric Nutritional Risk Index is a predictor of tolerability of antifibrotic therapy and mortality risk in patients with idiopathic pulmonary fibrosis
Yasutaka Mochizuka, Yuzo Suzuki, Masato Kono, Hirotsugu Hasegawa, Dai Hashimoto, Koshi Yokomura, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Hidenori Nakamura, Takafumi Suda
10.1111/resp.14523
More than a third of IPF patients had evidence of malnutrition at the initiation of antifibrotic therapy. Malnutrition reduced the tolerability of antifibrotic therapy and predicts early termination of antifibrotic treatment. Malnutrition is a risk factor of adverse outcome independent of age, sex, or FVC or gender–age–physiology index.
See related editorial |
| Sleep and Ventilation |
| 784 | Ketogenic diet acutely improves gas exchange and sleep apnoea in obesity hypoventilation syndrome: A non-randomized crossover study
Adam Osman, Chenjuan Gu, David E Kim, Daisy Duan, Bobbie Barron, Luu V Pham, Vsevolod Y Polotsky, Jonathan C Jun
10.1111/resp.14526
A ketogenic diet acutely improves carbon dioxide levels, sleep apnoea, and overnight oxygen in patients with obesity hypoventilation syndrome.
See related editorial |
| FORUM AND DEBATE |
| Scientific Letter |
| 794 | Endoscopic resection of tracheal and bronchial granular cell tumours: A national multicentre retrospective study
Samy Lachkar, Maxime Roger, Jean-Michel Vergnon, Adrian Crutu, Michel Febvre, Anas Mehdaoui, Radj Gervais, Laurence Geriniere, Francois Arbib, Charles Dayen, Valery Trosini-Desert, Julie Perrin, David Mispelaere, Luc Thiberville, Florian Guisier, Mathieu Salaun, on behalf of the French-Speaking Group on Thoracic Endoscopy (Groupe d'Endoscopie Thoracique et Interventionnel Francophone, GETIF) of the French Language Respiratory Society (Société de Pneumologie de Langue Française, SPLF)
10.1111/resp.14532 |
| Personal Reflections |
| 798 | Illness, chocolate and Harry Potter
Natasha Smallwood BMedSci, MBBS, MSc, AFRACMA, FRCP, FRACP, PhD, FThorSoc
10.1111/resp.14529 |
| 800 | The power of music
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| Letter from Asia-Pacific and Beyond |
| 802 | Letter from the Czech Republic
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| 804 | Bronchiectasis is associated with coronary artery calcification even in never smokers
Lewis Holmes, Isaac Lui, Paul Lilburn, Christopher Naoum, Leonard Kritharides, Lloyd Ridley, Lucy Morgan
10.1111/resp.14527 |
| MEETING REPORT |
| 807 | Towards regional progress: APSR 2022 Big Five Lung Diseases Workshop
Paul N Reynolds, Sameera Ansari, Rosalyn Hernandez-Sebastian, Watchara Boonsawat, Shih-Yu Chen, Landy Lan, Dawei Yang, G M Monsur Habib, Jennifer Ann Mendoza-Wi, Hung-Ling Huang, Le Thi Tuyet Lan, Nguyen Nhu Vinh, Maria Lowella F De Leon, Anne B Chang
10.1111/resp.14548 |
