| EDITORIALS |
| 122 | Too little, too late? The underuse of beta-blockers in COPD needs evidence to address clinical uncertainty
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| 124 | Home economics for COPD care
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| 126 | Detecting COPD using micro-spirometry and/or questionnaire
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| 128 | No fire without smoke: Are the children really out of the woods?
Andrew Bush MBBS (Hons), MA, MD, FHEA, FRCP, FRCPCH, FERS, FAPSR, ATSF; Samatha Sonnappa MD, DCH, MRCP, FRCPCH, PhD
10.1111/resp.13644 |
| 130 | Improving electromagnetic navigation: One nodule at a time
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| COMMENTARIES |
| 132 | COPD: Challenges and opportunities
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| 134 | The enigma of dyspnoea in COPD: A physiological perspective
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| INVITED REVIEW SERIES |
| Molecular Techniques for Respiratory Diseases |
| 137 | 'Omics': The new language in medicine that we all must learn
Yuben Moodley MB ChB, FCP, FRACP, MD, PhD; Ian A Yang MBBS (Hons), PhD, FRACP, FAPSR, FThorSoc, Grad Dip Clin Epid
10.1111/resp.13754 |
| 139 | Metabolomics in chronic lung diseases
Shabarinath Nambiar, Sze Bong How, Joel Gummer, Robert Trengove, Yuben Moodley
10.1111/resp.13530 |
| 149 | Molecular techniques for respiratory diseases: MicroRNA and extracellular vesicles
Yasuhiro Gon, Tetsuo Shimizu, Kenji Mizumura, Shuichiro Maruoka, Mari Hikichi
10.1111/resp.13756 |
| INVITED REVIEW |
| 161 | Rational oral corticosteroid use in adult severe asthma: A narrative review
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| ORIGINAL ARTICLES |
| COPD |
| 173 |
Underuse of beta-blockers by patients with COPD and co-morbid acute coronary syndrome: A nationwide follow-up study in New Zealand
Lianne Parkin, Joshua Quon, Katrina Sharples, David Barson, Jack Dummer
10.1111/resp.13662
In this nationwide study of patients with chronic obstructive pulmonary disease, only 56.6% of patients with an acute coronary syndrome hospitalization during follow-up received a beta-blocker in the subsequent 6 months. The proportions who received aspirin and a statin were much higher, suggesting a particular reluctance to prescribe beta-blockers. |
| 183 | Home-based pulmonary rehabilitation for COPD using minimal resources: An economic analysis
Angela T Burge, Anne E Holland, Christine F McDonald, Michael J Abramson, Catherine J Hill, Annemarie L Lee, Narelle S Cox, Rosemary Moore, Caroline Nicolson, Paul O'Halloran, Aroub Lahham, Rebecca Gillies, Ajay Mahal
10.1111/resp.13667
This economic evaluation compared a new home-based pulmonary rehabilitation model with traditional centre-based practice, demonstrating favourable results using both cost-utility and cost-effectiveness approaches. Regardless of programme location, completion of pulmonary rehabilitation was associated with a significant reduction in healthcare costs in the following 12 months. |
| 191 | Handheld flow meter improves COPD detectability regardless of using a conventional questionnaire: A split-sample validation study
Misuzu Fujita, Kengo Nagashima, Sho Takahashi, Kiminori Suzuki, Takehiko Fujisawa, Akira Hata
10.1111/resp.13602
This study confirms that a handheld flow meter (HFM) is significantly advantageous in detecting chronic obstructive pulmonary disease (COPD), regardless of the use of a conventional questionnaire. |
| Environmental and Occupational Lung Disease |
| 198 | Early life exposure to coal mine fire smoke emissions and altered lung function in young children
Jingyi Shao, Graeme R Zosky, Graham L Hall, Amanda J Wheeler, Shyamali Dharmage, Shannon Melody, Marita Dalton, Rachel E Foong, Tierney O'Sullivan, Grant J Williamson, Katherine Chappell, Michael J Abramson, Fay H Johnston
10.1111/resp.13617
We found modest evidence for an association between infant exposure to elevated particulate matter during a 6-week coal mine fire and reduced respiratory system reactance measured 3 years after the fire. The magnitude of the association was small, but of potential clinical importance in the most severely exposed children. |
| Interventional Pulmonology |
| 206 |
Improved diagnostic yield for lung nodules with digital tomosynthesis-corrected navigational bronchoscopy: Initial experience with a novel adjunct
Matt Aboudara, Lance Roller, Otis Rickman, Robert J Lentz, Jasleen Pannu, Heidi Chen, Fabien Maldonado
10.1111/resp.13609
Tomosynthesis-assisted navigational bronchoscopy using a conventional fluoroscopic C-arm is a new technique that can correct for nodule divergence but its impact on diagnostic yield is unproven. We performed a retrospective study evaluating this technology and found a 25% increase in diagnostic yield with small peripheral nodules. |
| Sleep and Ventilation |
| 214 | Assessing ventilatory control stability in children with and without an elevated central apnoea index
Katherine Harman, Aidan J Weichard, Margot J Davey, Rosemary S C Horne, Gillian M Nixon, Bradley A Edwards
10.1111/resp.13606
While central apnoeas are common in children, a central apnoea index of >5 events/h is outside normal ranges and raises concern regarding origins of such events. Our study indicates that an elevated index of >5 is associated with a hypersensitive ventilatory control system and supports literature that neuroimaging may not be needed. |
| LETTER FROM ASIA-PACIFIC AND BEYOND |
| 221 | Letter from the USA
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| FORUM AND DEBATE |
| Correspondence |
| 223 | Occupational hazards: Multidisciplinarity to make 'preventability' happen
Catherine Cavalin PhD, Alain Lescoat MD, Alfredo Menéndez-Navarro PhD, Paul-André Rosental PhD
10.1111/resp.13752 |
