| Page | |
| EDITORIALS |
| 507 | Dynamics of hyperinflation
|
| 509 | Airway inflammation and lung function in cystic fibrosis
|
| 511 | Lung cancer: Removing toxic dust from our environment
|
| COMMENTARIES |
| 513 | Air pollution and respiratory health—Do we really need more evidence?
|
| 515 | Lung cancer screening: The pulmonologist, the thoracic surgeon and working together in a team
Frazer Kirk MBBS, MSurg, Cheng He MBBS, BMedSc, FRACS, Andrie Stroebel MBChB, FC Cardio SA, MMED, FRACS
10.1111/resp.14496 |
| INVITED REVIEW |
| 518 | Contemporary Concise Review 2022: Sleep
|
| ORIGINAL ARTICLES |
| COPD |
| 525 | Impact of bronchoscopic lung volume reduction with endobronchial valves on dynamic hyperinflation: Results from the PIERCE study
Romane Fumat, Marion Dupuis, Siham Mallah, Valentin Heluain, Florent Favard, Yannick Simonneau, Matthieu Dusselier, Romain Barthes, Sandrine Pontier, Samia Collot, Gavin Plat, Thomas Egenod, Nicolas Guibert
10.1111/resp.14488
Bronchoscopic lung volume reduction using endobronchial valves leads to a decrease in dynamic hyperinflation; and these changes correlate with improvements in static parameters changes (target lobe volume reduction, residual volume, forced expiratory volume in 1 second, forced vital capacity). Dynamic hyperinflation decrease is deeper in most severe patients.
See related Editorial |
| Cystic Fibrosis |
| 533 | Anti-protease levels in cystic fibrosis are associated with lung function, recovery from pulmonary exacerbations and may be gender-related
Ama-Tawiah Essilfie, Neralee Houston, Pramila Maniam, Gunter Hartel, Satomi Okano, David W Reid
10.1111/resp.14450
Cystic fibrosis (CF) patients have impaired lung proteases and maintaining anti-protease: protease ratios is crucial in preventing tissue damage. Secretory leukocyte protease inhibitor (SLPI) is significantly reduced and neutrophil elastase increased in P. aeruginosa-infected female patients with CF; correlating with lung function decline. Antibiotic treatment restored SLPI levels and improved lung function.
See related Editorial |
| Environmental and Occupational Lung Disease |
| 543 |
Lung cancer screening an asbestos exposed population: Existing lung cancer risk criteria are not sufficient
Fraser J H Brims, Edward J A Harris, Conor Murray, Chellan Kumarasamy, Alice Ho, Brendan Adler, Peter Franklin, Nick H de Klerk
10.1111/resp.14487
This prospective cohort study of 1743 asbestos exposed individuals demonstrates that the population is at high risk for lung cancer regardless of smoking status, low dose CT screening is effective at identifying early-stage lung cancer in this population and existing lung cancer risk criteria do not capture this population adequately.
See related Editorial |
| Lung Function |
| 551 | Respiratory muscle metabolic activity on PET/CT correlates with obstructive ventilatory defect severity and prognosis in patients undergoing lung cancer surgery
Kinan El Husseini, Jean-Marc Baste, Anne-Charlotte Bouyeure-Petit, Elodie Lhuillier, Antoine Cuvelier, Pierre Decazes, Pierre Vera, Thomas Similowski, Maxime Patout
10.1111/resp.14475
Respiratory muscle activity quantitatively correlated to FEV1 and TLC in patients undergoing lung cancer surgery. Hypermetabolism was associated with poorer survival and may indicate respiratory fragility. Beyond cancer staging, 18F-FDG/PET-CT may improve risk stratification of patients by providing valuable information on respiratory muscle metabolism and appears worthy of further investigation. |
| Pleural Disease |
| 561 | Device assessed activity behaviours in patients with indwelling pleural catheter: A sub-study of the Australasian Malignant PLeural Effusion (AMPLE)-2 randomized trial
Carolyn J Peddle-McIntyre, Sanjeevan Muruganandan, Joanne McVeigh, Deirdre B Fitzgerald, Leon Straker, Robert U Newton, Kevin Murray, Yun Chor Gary Lee
10.1111/resp.14451
Accelerometry is a novel patient-centred outcome measure. Malignant pleural effusion patients are mostly sedentary. Those undergoing daily drainages of indwelling pleural catheter could have a better activity behaviour profile compared to those doing symptom guided drainages. A lower proportion of sedentary time was associated with better quality of life. |
| FORUM AND DEBATE |
| Scientific Letter |
| 571 | Monoclonal antibody therapy in cystic fibrosis and asthma
Huy Duc Vu, Eskandarain Shafuddin, Jane Willis, Michael Pallin, David Armstrong, Christopher Daley
10.1111/resp.14498 |
| Personal Reflections |
| 575 | How philanthropy can make you healthy and happy
|
| 577 | Spirometry, you have an image problem!
|
| 578 | The School of Athens
|
| Letter from Asia-Pacific and Beyond |
| 580 | Letter from Malta
Cynthia Farrugia Jones MD, FRCP(Lon), FRCP(Edin), PG Dip Med Ed (Dundee), Brendan Caruana Montalto MD, FACP
10.1111/resp.14483 |
| Correspondence |
| 582 | Effect of an artificial intelligence tool on management decisions for indeterminate pulmonary nodules
Roger Y Kim, Jason L Oke, Travis L Dotson, Christina R Bellinger, Anil Vachani
10.1111/resp.14502 |
