Respirology

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February 2015
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EDITOR'S CHOICE
175The Editor recommends this issue's articles to the reader
EDITORIALS
176Springing forward to medium-term results for endobronchial coils for emphysema
Pallav L Shah & Samuel V Kemp
179Promoting weight loss in asthma
Anne E Dixon & Lynn B Gerald
181First you have to row a little boat
Jennifer R Honda, Richard J Wallace Jr & Edward D Chan
SERIES EDITORIAL
Lung Cancer Practice, Implementing Evidence from Around the World
183Update in lung cancer: Prologue to a modern review series
Nico van Zandwijk & Kwun M Fong
INVITED REVIEW SERIES
Drug Development
185Pharmaceutical industry, academia and patient advocacy organizations: What is the recipe for synergic (win-win-win) collaborations?
Daniel M Rose, Richard Marshall & Mark W Surber
Lung Cancer Practice, Implementing Evidence from Around the World
192Multidisciplinary Lung Cancer Meetings: Improving the practice of radiation oncology and facing future challenges
Belinda A Campbell, David Ball & Françoise Mornex
199Implementation of modern therapy approaches and research for non-small cell lung cancer in Japan
Yoichi Nakanishi
Respiratory Disease: Using Lung Function Measurements to Greater Advantage
209Pulmonary physiology: Future directions for lung function testing in COPD
Vito Brusasco, Giovanni Barisione & Emanuele Crimi
REVIEWS
219Vitamin D binding protein genotype variants and risk of chronic obstructive pulmonary disease: A meta-analysis
Nobuyuki Horita, Naoki Miyazawa, Koji Tomaru, Miyo Inoue, Yoshiaki Ishigatsubo & Takeshi Kaneko
226Endobronchial ultrasound-guided transbronchial needle aspiration for diagnosis of sarcoidosis in clinically unselected study populations
Rocco Trisolini, Luigi Lazzari Agli, Carmine Tinelli, Annalisa De Silvestri, Valeria Scotti & Marco Patelli
235Portopulmonary hypertension: An update
Mateo Porres-Aguilar & Debabrata Mukherjee
ORIGINAL ARTICLES
Asthma and Allergy
243Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma
Hayley A Scott, Peter G Gibson, Manohar L Garg, Jeffrey J Pretto, Philip J Morgan, Robin Callister & Lisa G Wood
This study is the first to demonstrate that more severe asthma at baseline, male sex, and improvements in eating behaviours during weight loss are associated with greater weight loss success in overweight and obese adults with asthma.
Our findings may inform the development of asthma-specific weight management guidelines.
251Is non-invasive ventilation safe in acute severe asthma?
Michael Pallin, Mark Hew & Matthew T Naughton
The role of non-invasive ventilation in acute asthma is not well described and there are concerns about its safety. Over a 5-year period, non-invasive ventilation was used without significant complications in patients with moderate acute severe asthma.
258Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation
Qi-Ying Shen, Lei Fang, Hui-Mei Wu, Fang He, Pei-Shan Ding & Rong-Yu Liu
The effect of repeated administration of SVF on airway inflammation in a mouse model was evaluated. SVF treatment inhibited inflammatory cell infiltration and modulated the imbalance of HMGB1, TNF-α and IL-10 responses in the lung of sensitized mice.
264Budesonide/formoterol maintenance and reliever therapy in asthma control: Acute, dose-related effects and real-life effectiveness
Ching-Hsiung Lin, Jeng-Yuan Hsu, Yi-Han Hsiao, Ching-Min Tseng, Vincent Yi-Fong Su, Yu-Hsuan Chen, Sheau-Ning Yang, Yu-Chin Lee, Kang-Cheng Su & Diahn-Warng Perng
In steroid-naïve asthmatics, a single, higher dose of inhaled budesonide/formoterol (640/18 μg) as reliever exerts greater anti-inflammatory effects and FEV1 improvement within 6 h. Budesonide/formoterol maintenance and reliever therapy achieves significant improvement of asthma control 4 weeks post-treatment. However, long-term follow up remains an issue in real-life settings.
COPD
273Correlation between heart rate variability indexes and aerobic physiological variables in patients with COPD
Marceli R Leite, Ercy Mara C Ramos, Carlos A Kalva-Filho, Fernanda Maria M Rodrigues, Ana Paula C F Freire, Guilherme Y Tacao, Alessandra C de Toledo, Michel J Cecilio, Luiz Carlos M Vanderlei & Dionei Ramos
This study aimed to investigate whether the HRV indexes correlate with aerobic physiological variables obtained in cardiopulmonary exercise testing of patients with COPD Such correlation would have important clinical implications as it would allow, prior to the realization of the maximal exercise testing, to infer the patient's aerobic capacity
279Telemedicine, the effect of nurse-initiated telephone follow up, on health status and health-care utilization in COPD patients: A randomized trial
Farida F Berkhof, Jan W K van den Berg, Steven M Uil & Huib A M Kerstjens
Telemedicine has the potential to improve continuity of care, increase efficiency of outpatient management and prevent deterioration of health status in COPD patients. However, the effectiveness of telemedicine is still under debate.
This study demonstrated that telemedicine alone, without any form of education, pulmonary rehabilitation or training, had no benefits for COPD patients at all.
286Polymorphism of LRP5 gene and emphysema severity are associated with osteoporosis in Japanese patients with or at risk for COPD
Shotaro Chubachi, Hidetoshi Nakamura, Mamoru Sasaki, Mizuha Haraguchi, Masaki Miyazaki, Saeko Takahashi, Kyuto Tanaka, Yohei Funatsu, Koichiro Asano, Tomoko Betsuyaku & the Keio COPD Comorbidity Research (K-CCR) Group
Risk factors for COPD-associated osteoporosis are not fully elucidated. This observational COPD cohort study demonstrates that a polymorphism in low-density lipoprotein receptor-related protein 5 gene, female gender and the presence of severe emphysema are independent risk factors for low bone mineral density in patients with or at risk for COPD.
296Genetic variants of pulmonary SP-D predict disease outcome of COPD in a Chinese population
Chih-Ying Ou, Chiung-Zuei Chen, Tzuen-Ren Hsiue, Sheng-Hsiang Lin & Jiu-Yao Wang
We demonstrated for the first time in a Chinese population cohort that genetic polymorphisms of SP-D are not only associated with risk of COPD development, but also related to disease manifestation and that they predict outcomes.
304Tiotropium as part of inhaled polytherapy: Adherence and associated health-care utilization
Tzahit Simon-Tuval & Nimrod Maimon
A computerized medical database was used to estimate adherence of patients with COPD to inhaled therapy and health-care utilization following initiation of Tiotropium. Adherence to Tiotropium was associated with decreased hospitalizations only among patients who improved their adherence to additional inhaled therapy as well.
Cystic Fibrosis
312
Characterization of gene mutations and phenotypes of cystic fibrosis in Chinese patients
Yaping Liu, Lianqing Wang, Xinlun Tian, Kai-Feng Xu, Wenbing Xu, Xue Li, Cai Yue, Peng Zhang, Yi Xiao & Xue Zhang
We conducted research on seven Chinese cystic fibrosis patients. Their CFTR mutations are uncommon compared with those commonly found in Caucasians. Therefore, physicians in both China and western countries should pay more attention to atypically affected CF-like patients, especially those who are of Chinese origin.
Interventional Pulmonology
319
Long-term follow-up after bronchoscopic lung volume reduction treatment with coils in patients with severe emphysema
Jorine E Hartman, Karin Klooster, Kiki Gortzak, Nick H T ten Hacken & Dirk-Jan Slebos
This is the first study to investigate the safety and efficacy of the lung volume reduction coil treatment in the long term. At 3-year follow-up, this treatment showed no long-term unexpected adverse and device-related events, with clinical benefit gradually declining over time.
327Pleuroscopic cryoprobe biopsies of the pleura: A feasibility and safety study
Rajesh Thomas, Shanka Karunarathne, Barton Jennings, Sue Morey, Siaw Ming Chai, Y C Gary Lee & Martin J Phillips
This study evaluated a novel method to obtain pleural biopsies using a flexible cryoprobe during flexi-rigid pleuroscopy. It showed that cryoprobe pleural biopsy technique was safe and provided good quality diagnostic specimens. Its role as a useful adjunct or alternative to conventional pleural biopsies during flex-rigid pleuroscopy requires further evaluation.
333Endobronchial ultrasound learning curve in interventional pulmonary fellows
David R Stather, Alex Chee, Paul MacEachern, Elaine Dumoulin, Christopher A Hergott, Jacob Gelberg, Eric Folch, Adnan Majid, Anne V Gonzalez & Alain Tremblay
EBUS learning rates vary significantly between trainees and for individual procedure components. Improvements in performance measures are noted even after 200 clinical cases performed. This information can be utilized to guide individualized performance assessments and assist training programmes in ensuring adequate procedure volumes required for trainees to successfully complete these assessments.
Tuberculosis
340Tuberculin skin test and QuantiFERON-TB Gold In-tube Test for latent tuberculosis in Thai HIV-infected adults
Thana Khawcharoenporn, Anucha Apisarnthanarak, Benjawan Phetsuksiri, Janisara Rudeeaneksin, Sopa Srisungngam & Linda M. Mundy
Tuberculin skin test (TST) remains the diagnostic test for latent tuberculosis in interferon-gamma release assay (IGRA)-unavailable HIV care settings, but the cut-off for reactivity needs to be adjusted accordingly. Women and patients older than 52 years with non-reactive TST and long-term smokers with reactive TST should undergo additional IGRA testing.
SCIENTIFIC LETTERS
348Variable agreement among experts regarding Mycobacterium avium complex lung disease
Theodore K Marras, D Rebecca Prevots, Frances B Jamieson, Kevin L Winthrop & on behalf of the Pulmonary MAC Outcomes Group
352Selecting the increment size for a maximal incremental cycle test in patients with COPD
Jorine E Hartman, Dirk-Jan Slebos, H Marike Boezen, Mathieu H G de Greef, Huib A M Kerstjens & Nick H T ten Hacken

Index

2024 AprVol. 29 Issue 4
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2023 MarVol. 29 Supplement 1
ANZSRS/TSANZ Annual Scientific Meeting 2024
2024 FebVol. 29 Issue 2
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2023 DecVol. 28 Issue 12
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2023 NovVol. 28 Supplement 4
APSR 2023 Congress Abstracts
2023 OctVol. 28 Issue 10
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2023 MarVol. 28 Supplement 3
Australian Lung Cancer Conference 2023
2023 MarVol. 28 Supplement 2
ANZSRS/TSANZ Annual Scientific Meeting 2023
2023 FebVol. 28 Issue 2
2023 FebVol. 28 Supplement 1
APSR 2022 Congress Abstracts
2023 JanVol. 28 Issue 1
2022 DecVol. 27 Issue 12
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2022 OctVol. 27 Issue 10
2022 SepWorld Lung Day 2022
2022 SepVol. 27 Issue 9
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Special Issue: Occupational Lung Health
2022 MayVol. 27 Issue 5
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2022 FebVol. 27 Issue 2
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2021 OctVol. 26 Issue 10
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2018 NovVol. 23 Issue 11
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2018 SepVol. 23 Issue 9
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2018 JulVol. 23 Issue 7
2018 JunVol. 23 Issue 6
2018 MayVol. 23 Issue 5
2018 AprVol. 23 Issue 4
2018 MarVol. 23 Supplement 1
ANZSRS and TSANZ abstracts
2018 MarVol. 23 Issue 3
2018 FebVol. 23 Issue 2
2018 JanVol. 23 Issue 1
2017 NovVol. 22 Supplement 3
APSR Congress Abstracts
2017 NovVol. 22 Issue 8
2017 OctVol. 22 Issue 7
2017 AugVol. 22 Issue 6
2017 JulyVol. 22 Issue 5
2017 MayVol. 22 Issue 4
2017 AprVol. 22 Issue 3
2017 MarVol. 22 Supplement 2
ANZSRS and TSANZ abstracts
2017 MarVol. 22 Supplement 1
Airway Vista abstracts
2017 FebVol. 22 Issue 2
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APSR Congress Abstracts
2016 NovVol. 21 Issue 8
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2016 AugVol. 21 Issue 6
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2016 AprVol. 21 Supplement 2
ANZSRS and TSANZ abstracts
2016 AprVol. 21 Issue 3
2016 MarVol. 21 Supplement 1
Airway Vista abstracts
2016 FebVol. 21 Issue 2
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2015 DecVol. 20 Supplement 3
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2015 NovVol. 20 Issue 8
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2015 MarVol. 20 Supplement 1
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2015 FebVol. 20 Issue 2
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2014 NovVol. 19 Issue 8
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APSR Congress Abstracts
2014 OctVol. 19 Issue 7
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ANZSRS and TSANZ abstracts
2014 MarVol. 19 Supplement 1
Airway Inflammation
2014 FebVol. 19 Issue 2
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2013 NovVol. 18 Issue 8
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APSR Congress Abstracts
2013 NovVol. 18 Supplement 3
Airway Inflammation
2013 OctVol. 18 Issue 7
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2011 OctVol. 16 Issue 7
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2010 NovVol. 15 Issue 8
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2010 FebVol. 15 Issue 2
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2009 NovVol. 14 Issue 8
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2009 OctVol. 14 Supplement 2
Guidelines: Hospital-Acquired Pneumonia
2009 SepVol. 14 Issue 7
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2009 MarVol. 14 Issue 2
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2008 NovVol. 13 Issue 7
2008 NovVol. 13 Supplement 5
APSR Congress Abstracts
2008 NovVol. 13 Supplement 4
Lung Disease
2008 SepVol. 13 Issue 6
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ESAP: TB
2008 JulVol. 13 Issue 5
2008 JunVol. 13 Issue 4
2008 MayVol. 13 Issue 3
2008 AprVol. 13 Supplement 2
ANZSRS and TSANZ Abstracts
2008 MarVol. 13 Supplement 1
ESAP Abstracts
2008 MarVol. 13 Issue 2
2008 JanVol. 13 Issue 1
2007 NovVol. 12 Supplement 4
APSR Congress Abstracts
2007 NovVol. 12 Supplement 3
Asthma
2007 NovVol. 12 Issue 6
2007 SepVol. 12 Issue 5
2007 JulVol. 12 Issue 4
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ESAP Abstracts
2007 MayVol. 12 Issue 3
2007 MarVol. 12 Supplement 1
ANZSRS and TSANZ Abstracts
2007 MarVol. 12 Issue 2
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APSR Congress Abstracts
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Guidelines: Cough
2006 SepVol. 11 Supplement 3
Guidelines: Respiratory Infections
2006 SepVol. 11 Issue 5
2006 JulVol. 11 Issue 4
2006 MayVol. 11 Issue 3
2006 MarVol. 11 Supplement 2
ANZSRS and TSANZ abstracts
2006 MarVol. 11 Issue 2
2006 JanVol. 11 Supplement 1
Surfactant Molecular Pathophysiology
2006 JanVol. 11 Issue 1
2005 NovVol. 10 Supplement 3
APSR Congress Abstracts
2005 NovVol. 10 Supplement 2
Respiratory function tests
2005 NovVol. 10 Issue 5
2005 SepVol. 10 Issue 4
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ANZSRS and TSANZ abstracts
2005 MarVol. 10 Issue 2
2005 JanVol. 10 Issue 1
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APSR Congress Abstracts
2004 NovVol. 9 Issue 4
2004 AugVol. 9 Issue 3
2004 JunVol. 9 Issue 2
2004 MarVol. 9 Supplement 2
APSR Congress Abstracts
2004 MarVol. 9 Supplement 1
Guidelines: Hospital-Acquired Pneumonia
2004 MarVol. 9 Issue 1
2003 DecVol. 8 Issue 4
2003 NovVol. 8 Supplement 1
SARS
2003 SepVol. 8 Issue 3
2003 JunVol. 8 Issue 2
2003 AprVol. 8 Supplement 2
APSR Congress Abstracts
2003 MarVol. 8 Issue 1
2002 DecVol. 7 Issue 4
2002 SepVol. 7 Issue 3
2002 JunVol. 7 Issue 2
2002 MarVol. 7 Supplement 1
APSR Congress Abstracts
2002 MarVol. 7 Issue 1
2001 DecVol. 6 Issue 4
2001 SepVol. 6 Issue 3
2001 JunVol. 6 Supplement 2
Chronic Obstructive Lung Diseases
2001 JunVol. 6 Issue 2
2001 MarVol. 6 Issue 1
2000 DecVol. 5 Issue 4
2000 SepVol. 5 Issue 3
2000 JunVol. 5 Issue 2
2000 JunVol. 05 Supplement 2
TSANZ abstracts
2000 AprVol. 05 Supplement 1
TSANZ abstracts
2000 MarVol. 5 Issue 1
1999 DecVol. 4 Issue 4
1999 SepVol. 4 Issue 3
1999 JunVol. 4 Issue 2
1999 AprVol. 04 Supplement 1
TSANZ abstracts
1999 JanVol. 4 Issue 1
1998 DecVol. 3 Issue 4
1998 SepVol. 3 Issue 3
1998 JunVol. 3 Issue 2
1998 MarVol. 3 Issue 1
1997 DecVol. 2 Issue 4
1997 SepVol. 2 Issue 3
1997 JunVol. 2 Issue 2
1997 MarVol. 2 Issue 1
1996 DecVol. 1 Issue 4
1996 SepVol. 1 Issue 3
1996 JunVol. 1 Issue 2
1996 MarVol. 1 Issue 1