EDITORIALS |
240 | Moving pulmonary rehabilitation forward in COPD: Stepping towards (home-based) action
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242 | Endobronchial valve placement in emphysema: When is it lung volume reduction?
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244 | Treatment doses in idiopathic pulmonary fibrosis: The devil is in the detail
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COMMENTARY |
246 | Management of venous thromboembolism: Time to measure our performance
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INVITED REVIEW SERIES |
Respiratory Infections in the Asia-Pacific Region |
248 | Respiratory infections in the Asia-Pacific region: Problems and cautious optimism
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250 | Pneumonia as a cardiovascular disease
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Seeking Innovative Solutions in Severe Asthma |
260 | Severe asthma: We can fix it? We can try!
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262 | Pathophysiology of severe asthma: We've only just started
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SYSTEMATIC REVIEW |
272 | Comparison of outpatient and home-based exercise training programmes for COPD: A systematic review and meta-analysis
Francesca Wuytack, Declan Devane, Elizabeth Stovold, Melissa McDonnell, Michelle Casey, Timothy J McDonnell, Paddy Gillespie, Adam Raymakers, Yves Lacasse and Bernard McCarthy
10.1111/resp.13224 |
ORIGINAL ARTICLES |
Asthma and Allergy |
284 | Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma
Sarah Todd, Emil S Walsted, Lizzie Grillo, Rebecca Livingston, Andrew Menzies-Gow and James H Hull
10.1111/resp.13173
Breathing pattern disorder (BPD) can coexist with and mimic asthma, amplifying symptoms, leading to inappropriate treatment escalation. This study reveals that BPD is highly prevalent in treatment-refractory asthma and can be characterized using a breathing pattern assessment tool (BPAT). The BPAT is easy to complete and promotes physiotherapy intervention. |
291 |
Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma
Andreas S Lappas, Anna S Tzortzi, Efstathia M Konstantinidi, Stephanie I Teloniatis, Chara K Tzavara, Sofia A Gennimata, Nikolaos G Koulouris and Panagiotis K Behrakis
10.1111/resp.13180
E-cigarette smoking (ECS) has immediate mechanical and inflammatory consequences in smokers, with more prominent duration and intensity in mild asthma (MA). ECS and MA also had synergistic effects on respiratory function. These findings have implications for asthma management and tobacco control.
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COPD |
298 | Surfactant protein D multimerization and gene polymorphism in COPD and asthma
Dalia Fakih, Zeina Akiki, Kirsten Junker, Myrna Medlej-Hashim, Mirna Waked, Pascale Salameh, Uffe Holmskov, Hasnaa Bouharoun-Tayoun, Soulaima Chamat, Grith L Sorensen and Rania Jounblat
10.1111/resp.13193
We demonstrated for the first time in a Lebanese population cohort that non-multimerized species of serum surfactant protein D (SP-D) were dominant in Met11/Met11 COPD and asthmatic patients suggesting that degradation of SP-D takes place to a significant degree in pulmonary diseases. |
306 | Minimal important difference of target lobar volume reduction after endobronchial valve treatment for emphysema
Jorrit B A Welling, Jorine E Hartman, Eva M van Rikxoort, Nick H T Ten Hacken, Huib A M Kerstjens, Karin Klooster and Dirk-Jan Slebos
10.1111/resp.13178
The minimal important difference (MID) for target lobar volume reduction after endobronchial valve treatment for emphysema is -563 mL. This MID can be useful for both interpreting the results from trials and clinical practice, as well as for designing future studies on lung volume reduction. |
Interstitial Lung Disease |
311 |
Unfavourable outcome of glucocorticoid treatment in suspected idiopathic pulmonary fibrosis
Ivo A Wiertz, Wim A Wuyts, Coline H M van Moorsel, Adriane D M Vorselaars, Hendrik W van Es, Matthijs F M van Oosterhout and Jan C Grutters
10.1111/resp.13230
Evidence is lacking to guide treatment of patients with suspected idiopathic pulmonary fibrosis (IPF) who have radiological inconsistent usual interstitial pneumonia (UIP) and UIP pattern in surgical lung biopsy. In this retrospective cohort, these patients demonstrated an accelerated decline in forced vital capacity (FVC) and multiple serious adverse events when treated with prednisone.
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318 | Body size-adjusted dose analysis of pirfenidone in patients with interstitial pneumonia
Masahiro Uehara, Noriyuki Enomoto, Yoshiyuki Oyama, Yuzo Suzuki, Masato Kono, Kazuki Furuhashi, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura and Takafumi Suda
10.1111/resp.13145
Patients with interstitial pneumonia (IP) and adverse effects received a significantly higher dose of pirfenidone adjusted by body surface area and body weight. In a subgroup of patients with idiopathic pulmonary fibrosis (IPF), a high/medium dose was associated with a lower decline in % forced vital capacity (FVC). Body size-adjusted dosing may be beneficial for the treatment of IP. |
325 | Serial chest CT in cryptogenic organizing pneumonia: Evolutional changes and prognostic determinants
Man P Chung, Bo D Nam, Kyung S Lee, Joungho Han, Jai S Park, Jung H Hwang, Min J Cha and Tae J Kim
10.1111/resp.13188
In patients with cryptogenic organizing pneumonia, 77% had residual computed tomography (CT) abnormalities on follow-up CT chest, even after corticosteroid treatment. The extent of lung abnormalities, consolidation on CT, diffusion measurements and treatment duration were factors associated with residual CT abnormalities. |
Rare Lung Disease |
331 | Efficacy and safety of transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: A report of 24 consecutive patients
Taro Koba, Toru Arai, Masanori Kitaichi, Takahiko Kasai, Masaki Hirose, Kazunobu Tachibana, Chikatoshi Sugimoto, Masanori Akira, Seiji Hayashi and Yoshikazu Inoue
10.1111/resp.13190
The diagnosis yield for lymphangioleiomyomatosis by transbronchial lung biopsy (TBLB) was 70.8%. The yield of TBLB was higher in patients with a reduced diffusing capacity, suggesting that an adequate disease burden is required for this approach. The procedure seems safe, as no serious adverse events such as pneumothorax or excessive bleeding were observed. |
LETTER FROM ASIA-PACIFIC REGION |
339 | Letter from New Zealand ... and Season's greetings
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CORRESPONDENCE |
341 | Serum YKL-40 in workers at an indium-tin oxide production facility
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342 | Serum YKL-40 in workers at an indium-tin oxide production facility – Reply
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