Respirology

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March 2018
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EDITORIALS
240Moving pulmonary rehabilitation forward in COPD: Stepping towards (home-based) action
Christian R Osadnik
10.1111/resp.13247
242Endobronchial valve placement in emphysema: When is it lung volume reduction?
Ralf Eberhardt
10.1111/resp.13217
244Treatment doses in idiopathic pulmonary fibrosis: The devil is in the detail
Athol U Wells and Katerina M Antoniou
10.1111/resp.13182
COMMENTARY
246Management of venous thromboembolism: Time to measure our performance
Michael W Y Tan, Sanjeev Chunilal and Darren Mansfield
10.1111/resp.13257
INVITED REVIEW SERIES
Respiratory Infections in the Asia-Pacific Region
248Respiratory infections in the Asia-Pacific region: Problems and cautious optimism
Grant Waterer
10.1111/resp.13238
250Pneumonia as a cardiovascular disease
Marcos I Restrepo and Luis F Reyes
10.1111/resp.13233
Seeking Innovative Solutions in Severe Asthma
260Severe asthma: We can fix it? We can try!
Vanessa M McDonald, Steven Maltby and Peter G Gibson
10.1111/resp.13249
262Pathophysiology of severe asthma: We've only just started
Gregory G King, Alan James, Louise Harkness and Peter A B Wark
10.1111/resp.13251
SYSTEMATIC REVIEW
272Comparison of outpatient and home-based exercise training programmes for COPD: A systematic review and meta-analysis
Francesca Wuytack, Declan Devane, Elizabeth Stovold, Melissa McDonnell, Michelle Casey, Timothy J McDonnell, Paddy Gillespie, Adam Raymakers, Yves Lacasse and Bernard McCarthy
10.1111/resp.13224
ORIGINAL ARTICLES
Asthma and Allergy
284Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma
Sarah Todd, Emil S Walsted, Lizzie Grillo, Rebecca Livingston, Andrew Menzies-Gow and James H Hull
10.1111/resp.13173

Breathing pattern disorder (BPD) can coexist with and mimic asthma, amplifying symptoms, leading to inappropriate treatment escalation. This study reveals that BPD is highly prevalent in treatment-refractory asthma and can be characterized using a breathing pattern assessment tool (BPAT). The BPAT is easy to complete and promotes physiotherapy intervention.

291
Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma
Andreas S Lappas, Anna S Tzortzi, Efstathia M Konstantinidi, Stephanie I Teloniatis, Chara K Tzavara, Sofia A Gennimata, Nikolaos G Koulouris and Panagiotis K Behrakis
10.1111/resp.13180

E-cigarette smoking (ECS) has immediate mechanical and inflammatory consequences in smokers, with more prominent duration and intensity in mild asthma (MA). ECS and MA also had synergistic effects on respiratory function. These findings have implications for asthma management and tobacco control.

COPD
298Surfactant protein D multimerization and gene polymorphism in COPD and asthma
Dalia Fakih, Zeina Akiki, Kirsten Junker, Myrna Medlej-Hashim, Mirna Waked, Pascale Salameh, Uffe Holmskov, Hasnaa Bouharoun-Tayoun, Soulaima Chamat, Grith L Sorensen and Rania Jounblat
10.1111/resp.13193

We demonstrated for the first time in a Lebanese population cohort that non-multimerized species of serum surfactant protein D (SP-D) were dominant in Met11/Met11 COPD and asthmatic patients suggesting that degradation of SP-D takes place to a significant degree in pulmonary diseases.

306Minimal important difference of target lobar volume reduction after endobronchial valve treatment for emphysema
Jorrit B A Welling, Jorine E Hartman, Eva M van Rikxoort, Nick H T Ten Hacken, Huib A M Kerstjens, Karin Klooster and Dirk-Jan Slebos
10.1111/resp.13178

The minimal important difference (MID) for target lobar volume reduction after endobronchial valve treatment for emphysema is -563 mL. This MID can be useful for both interpreting the results from trials and clinical practice, as well as for designing future studies on lung volume reduction.

Interstitial Lung Disease
311
Unfavourable outcome of glucocorticoid treatment in suspected idiopathic pulmonary fibrosis
Ivo A Wiertz, Wim A Wuyts, Coline H M van Moorsel, Adriane D M Vorselaars, Hendrik W van Es, Matthijs F M van Oosterhout and Jan C Grutters
10.1111/resp.13230

Evidence is lacking to guide treatment of patients with suspected idiopathic pulmonary fibrosis (IPF) who have radiological inconsistent usual interstitial pneumonia (UIP) and UIP pattern in surgical lung biopsy. In this retrospective cohort, these patients demonstrated an accelerated decline in forced vital capacity (FVC) and multiple serious adverse events when treated with prednisone.

318Body size-adjusted dose analysis of pirfenidone in patients with interstitial pneumonia
Masahiro Uehara, Noriyuki Enomoto, Yoshiyuki Oyama, Yuzo Suzuki, Masato Kono, Kazuki Furuhashi, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura and Takafumi Suda
10.1111/resp.13145

Patients with interstitial pneumonia (IP) and adverse effects received a significantly higher dose of pirfenidone adjusted by body surface area and body weight. In a subgroup of patients with idiopathic pulmonary fibrosis (IPF), a high/medium dose was associated with a lower decline in % forced vital capacity (FVC). Body size-adjusted dosing may be beneficial for the treatment of IP.

325Serial chest CT in cryptogenic organizing pneumonia: Evolutional changes and prognostic determinants
Man P Chung, Bo D Nam, Kyung S Lee, Joungho Han, Jai S Park, Jung H Hwang, Min J Cha and Tae J Kim
10.1111/resp.13188

In patients with cryptogenic organizing pneumonia, 77% had residual computed tomography (CT) abnormalities on follow-up CT chest, even after corticosteroid treatment. The extent of lung abnormalities, consolidation on CT, diffusion measurements and treatment duration were factors associated with residual CT abnormalities.

Rare Lung Disease
331Efficacy and safety of transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: A report of 24 consecutive patients
Taro Koba, Toru Arai, Masanori Kitaichi, Takahiko Kasai, Masaki Hirose, Kazunobu Tachibana, Chikatoshi Sugimoto, Masanori Akira, Seiji Hayashi and Yoshikazu Inoue
10.1111/resp.13190

The diagnosis yield for lymphangioleiomyomatosis by transbronchial lung biopsy (TBLB) was 70.8%. The yield of TBLB was higher in patients with a reduced diffusing capacity, suggesting that an adequate disease burden is required for this approach. The procedure seems safe, as no serious adverse events such as pneumothorax or excessive bleeding were observed.

LETTER FROM ASIA-PACIFIC REGION
339Letter from New Zealand ... and Season's greetings
CORRESPONDENCE
341Serum YKL-40 in workers at an indium-tin oxide production facility
R Reid Harvey, Brie M Hawley, M Abbas Virji and Kristin J Cummings
10.1111/resp.13236
342Serum YKL-40 in workers at an indium-tin oxide production facility – Reply
Francesco Bonella, Ulrich Costabel and on behalf of all co-authors
10.1111/resp.13237

Index

2024 MayVol. 29 Issue 5
2024 AprVol. 29 Issue 4
2024 MarVol. 29 Issue 3
2023 MarVol. 29 Supplement 1
ANZSRS/TSANZ Annual Scientific Meeting 2024
2024 FebVol. 29 Issue 2
2024 JanVol. 29 Issue 1
2023 DecVol. 28 Issue 12
2023 NovVol. 28 Issue 11
2023 NovVol. 28 Supplement 4
APSR 2023 Congress Abstracts
2023 OctVol. 28 Issue 10
2023 SepVol. 28 Issue 9
2023 AugVol. 28 Issue 8
2023 JulVol. 28 Issue 7
2023 JunVol. 28 Issue 6
2023 MayVol. 28 Issue 5
2023 AprVol. 28 Issue 4
2023 MarVol. 28 Issue 3
2023 MarVol. 28 Supplement 3
Australian Lung Cancer Conference 2023
2023 MarVol. 28 Supplement 2
ANZSRS/TSANZ Annual Scientific Meeting 2023
2023 FebVol. 28 Issue 2
2023 FebVol. 28 Supplement 1
APSR 2022 Congress Abstracts
2023 JanVol. 28 Issue 1
2022 DecVol. 27 Issue 12
2022 NovVol. 27 Issue 11
2022 OctVol. 27 Issue 10
2022 SepWorld Lung Day 2022
2022 SepVol. 27 Issue 9
2022 AugVol. 27 Issue 8
2022 JulVol. 27 Issue 7
2022 JunVol. 27 Issue 6
Special Issue: Occupational Lung Health
2022 MayVol. 27 Issue 5
2022 AprVol. 27 Issue 4
2022 MarVol. 27 Issue 3
2022 MarVol. 27 Issue s1
ANZSRS and TSANZ abstracts
2022 FebVol. 27 Issue 2
2022 JanVol. 27 Issue 1
2021 DecVol. 26 Issue 12
2021 NovVol. 26 Issue 11
2021 NovVol. 26 Supplement 3
APSR Congress Abstracts
2021 OctVol. 26 Issue 10
2021 SepVol. 26 Issue 9
2021 AugVol. 26 Issue 8
2021 JulVol. 26 Issue 7
2021 JunVol. 26 Issue 6
2021 MayVol. 26 Issue 5
2021 AprVol. 26 Issue 4
2021 AprVol. 26 Issue s2
ANZSRS and TSANZ abstracts
2021 MarVol. 26 Issue 3
2021 FebVol. 26 Issue 2
2021 JanVol. 26 Issue s1
Supplement: APSR Assembly Virtual Meetings
2021 JanVol. 26 Issue 1
2020 DecVol. 25 Issue 12
2020 NovVol. 25 Issue 11
2020 NovVol. 25 Issue s2
Essential update in lung cancer medicine
2020 OctVol. 25 Issue 10
2020 SepVol. 25 Issue 9
Special issue: Interventional Pulmonoogy pearls
2020 AugVol. 25 Issue 8
2020 JulVol. 25 Issue 7
2020 JunVol. 25 Issue 6
2020 JunVol. 25 Supplement 1
ANZSRS and TSANZ abstracts
2020 MayVol. 25 Issue 5
2020 AprVol. 25 Issue 4
2020 MarVol. 25 Issue 3
2020 FebVol. 25 Issue 2
2020 JanVol. 25 Issue 1
2019 DecVol. 24 Issue 12
2019 NovVol. 24 Issue 11
2019 NovVol. 24 Supplement 2
APSR Congress Abstracts
2019 OctVol. 24 Issue 10
2019 SepVol. 24 Issue 9
2019 AugVol. 24 Issue 8
2019 JulVol. 24 Issue 7
2019 JunVol. 24 Issue 6
2019 MayVol. 24 Issue 5
2019 AprVol. 24 Issue 4
2019 MarVol. 24 Issue 3
2019 MarVol. 24 Supplement 1
ANZSRS and TSANZ abstracts
2019 FebVol. 24 Issue 2
2019 JanVol. 24 Issue 1
2018 DecVol. 23 Issue 12
2018 NovVol. 23 Supplement 2
APSR Congress Abstracts
2018 NovVol. 23 Issue 11
2018 OctVol. 23 Issue 10
2018 SepVol. 23 Issue 9
2018 AugVol. 23 Issue 8
2018 JulVol. 23 Issue 7
2018 JunVol. 23 Issue 6
2018 MayVol. 23 Issue 5
2018 AprVol. 23 Issue 4
2018 MarVol. 23 Supplement 1
ANZSRS and TSANZ abstracts
2018 MarVol. 23 Issue 3
2018 FebVol. 23 Issue 2
2018 JanVol. 23 Issue 1
2017 NovVol. 22 Supplement 3
APSR Congress Abstracts
2017 NovVol. 22 Issue 8
2017 OctVol. 22 Issue 7
2017 AugVol. 22 Issue 6
2017 JulyVol. 22 Issue 5
2017 MayVol. 22 Issue 4
2017 AprVol. 22 Issue 3
2017 MarVol. 22 Supplement 2
ANZSRS and TSANZ abstracts
2017 MarVol. 22 Supplement 1
Airway Vista abstracts
2017 FebVol. 22 Issue 2
2017 JanVol. 22 Issue 1
2016 NovVol. 21 Supplement 3
APSR Congress Abstracts
2016 NovVol. 21 Issue 8
2016 OctVol. 21 Issue 7
2016 AugVol. 21 Issue 6
2016 JulVol. 21 Issue 5
2016 MayVol. 21 Issue 4
2016 AprVol. 21 Supplement 2
ANZSRS and TSANZ abstracts
2016 AprVol. 21 Issue 3
2016 MarVol. 21 Supplement 1
Airway Vista abstracts
2016 FebVol. 21 Issue 2
2016 JanVol. 21 Issue 1
2015 DecVol. 20 Supplement 3
APSR Congress Abstracts
2015 NovVol. 20 Issue 8
2015 OctVol. 20 Issue 7
2015 AugVol. 20 Issue 6
2015 JulVol. 20 Issue 5
2015 MayVol. 20 Issue 4
2015 AprVol. 20 Issue 3
2015 MarVol. 20 Supplement 2
ANZSRS and TSANZ abstracts
2015 MarVol. 20 Supplement 1
Airway Vista abstracts
2015 FebVol. 20 Issue 2
2015 JanVol. 20 Issue 1
2014 NovVol. 19 Issue 8
2014 NovVol. 19 Supplement 3
APSR Congress Abstracts
2014 OctVol. 19 Issue 7
2014 AugVol. 19 Issue 6
2014 JulVol. 19 Issue 5
2014 MayVol. 19 Issue 4
2014 AprVol. 19 Issue 3
2014 AprVol. 19 Supplement 2
ANZSRS and TSANZ abstracts
2014 MarVol. 19 Supplement 1
Airway Inflammation
2014 FebVol. 19 Issue 2
2014 JanVol. 19 Issue 1
2013 NovVol. 18 Issue 8
2013 OctVol. 18 Supplement 4
APSR Congress Abstracts
2013 NovVol. 18 Supplement 3
Airway Inflammation
2013 OctVol. 18 Issue 7
2013 AugVol. 18 Issue 6
2013 JulVol. 18 Issue 5
2013 MayVol. 18 Issue 4
2013 AprVol. 18 Issue 3
2013 AprVol. 18 Supplement 2
ANZSRS and TSANZ abstracts
2013 AprVol. 18 Supplement 1
Airway Vista abstracts
2013 FebVol. 18 Issue 2
2013 JanVol. 18 Issue 1
2012 DecVol. 17 Supplement 2
APSR Congress Abstracts
2012 NovVol. 17 Issue 8
2012 OctVol. 17 Issue 7
2012 AugVol. 17 Issue 6
2012 JulVol. 17 Issue 5
2012 MayVol. 17 Issue 4
2012 AprVol. 17 Issue 3
2012 AprVol. 17 Supplement 1
ANZSRS and TSANZ abstracts
2012 FebVol. 17 Issue 2
2012 JanVol. 17 Issue 1
2011 NovVol. 16 Issue 8
2011 NovVol. 16 Supplement 2
APSR Congress Abstracts
2011 OctVol. 16 Issue 7
2011 AugVol. 16 Issue 6
2011 JulVol. 16 Issue 5
2011 MayVol. 16 Issue 4
2011 AprVol. 16 Issue 3
2011 AprVol. 16 Supplement 1
ANZSRS and TSANZ abstracts
2011 FebVol. 16 Issue 2
2011 JanVol. 16 Issue 1
2010 NovVol. 15 Supplement 2
APSR Congress Abstracts
2010 NovVol. 15 Issue 8
2010 OctVol. 15 Issue 7
2010 AugVol. 15 Issue 6
2010 JulVol. 15 Issue 5
2010 MayVol. 15 Issue 4
2010 AprVol. 15 Issue 3
2010 MarVol. 15 Supplement 1
ANZSRS and TSANZ abstracts
2010 FebVol. 15 Issue 2
2010 JanVol. 15 Issue 1
2009 NovVol. 14 Issue 8
2009 NovVol. 14 Supplement 3
APSR Congress Abstracts
2009 OctVol. 14 Supplement 2
Guidelines: Hospital-Acquired Pneumonia
2009 SepVol. 14 Issue 7
2009 Vol. 14 Issue 6
2009 JulVol. 14 Issue 5
2009 MayVol. 14 Issue 4
2009 AprVol. 14 Issue 3
2009 AprVol. 14 Supplement 1
ANZSRS and TSANZ abstracts
2009 MarVol. 14 Issue 2
2009 JanVol. 14 Issue 1
2008 NovVol. 13 Issue 7
2008 NovVol. 13 Supplement 5
APSR Congress Abstracts
2008 NovVol. 13 Supplement 4
Lung Disease
2008 SepVol. 13 Issue 6
2008 SepVol. 13 Supplement 3
ESAP: TB
2008 JulVol. 13 Issue 5
2008 JunVol. 13 Issue 4
2008 MayVol. 13 Issue 3
2008 AprVol. 13 Supplement 2
ANZSRS and TSANZ Abstracts
2008 MarVol. 13 Supplement 1
ESAP Abstracts
2008 MarVol. 13 Issue 2
2008 JanVol. 13 Issue 1
2007 NovVol. 12 Supplement 4
APSR Congress Abstracts
2007 NovVol. 12 Supplement 3
Asthma
2007 NovVol. 12 Issue 6
2007 SepVol. 12 Issue 5
2007 JulVol. 12 Issue 4
2007 MayVol. 12 Supplement 2
ESAP Abstracts
2007 MayVol. 12 Issue 3
2007 MarVol. 12 Supplement 1
ANZSRS and TSANZ Abstracts
2007 MarVol. 12 Issue 2
2007 JanVol. 12 Issue 1
2006 NovVol. 11 Supplement 5
APSR Congress Abstracts
2006 NovVol. 11 Issue 6
2006 SepVol. 11 Supplement 4
Guidelines: Cough
2006 SepVol. 11 Supplement 3
Guidelines: Respiratory Infections
2006 SepVol. 11 Issue 5
2006 JulVol. 11 Issue 4
2006 MayVol. 11 Issue 3
2006 MarVol. 11 Supplement 2
ANZSRS and TSANZ abstracts
2006 MarVol. 11 Issue 2
2006 JanVol. 11 Supplement 1
Surfactant Molecular Pathophysiology
2006 JanVol. 11 Issue 1
2005 NovVol. 10 Supplement 3
APSR Congress Abstracts
2005 NovVol. 10 Supplement 2
Respiratory function tests
2005 NovVol. 10 Issue 5
2005 SepVol. 10 Issue 4
2005 JunVol. 10 Issue 3
2005 MarVol. 10 Supplement 1
ANZSRS and TSANZ abstracts
2005 MarVol. 10 Issue 2
2005 JanVol. 10 Issue 1
2004 DecVol. 9 Supplement 3
APSR Congress Abstracts
2004 NovVol. 9 Issue 4
2004 AugVol. 9 Issue 3
2004 JunVol. 9 Issue 2
2004 MarVol. 9 Supplement 2
APSR Congress Abstracts
2004 MarVol. 9 Supplement 1
Guidelines: Hospital-Acquired Pneumonia
2004 MarVol. 9 Issue 1
2003 DecVol. 8 Issue 4
2003 NovVol. 8 Supplement 1
SARS
2003 SepVol. 8 Issue 3
2003 JunVol. 8 Issue 2
2003 AprVol. 8 Supplement 2
APSR Congress Abstracts
2003 MarVol. 8 Issue 1
2002 DecVol. 7 Issue 4
2002 SepVol. 7 Issue 3
2002 JunVol. 7 Issue 2
2002 MarVol. 7 Supplement 1
APSR Congress Abstracts
2002 MarVol. 7 Issue 1
2001 DecVol. 6 Issue 4
2001 SepVol. 6 Issue 3
2001 JunVol. 6 Supplement 2
Chronic Obstructive Lung Diseases
2001 JunVol. 6 Issue 2
2001 MarVol. 6 Issue 1
2000 DecVol. 5 Issue 4
2000 SepVol. 5 Issue 3
2000 JunVol. 5 Issue 2
2000 JunVol. 05 Supplement 2
TSANZ abstracts
2000 AprVol. 05 Supplement 1
TSANZ abstracts
2000 MarVol. 5 Issue 1
1999 DecVol. 4 Issue 4
1999 SepVol. 4 Issue 3
1999 JunVol. 4 Issue 2
1999 AprVol. 04 Supplement 1
TSANZ abstracts
1999 JanVol. 4 Issue 1
1998 DecVol. 3 Issue 4
1998 SepVol. 3 Issue 3
1998 JunVol. 3 Issue 2
1998 MarVol. 3 Issue 1
1997 DecVol. 2 Issue 4
1997 SepVol. 2 Issue 3
1997 JunVol. 2 Issue 2
1997 MarVol. 2 Issue 1
1996 DecVol. 1 Issue 4
1996 SepVol. 1 Issue 3
1996 JunVol. 1 Issue 2
1996 MarVol. 1 Issue 1