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| EDITORIALS |
| 632 | Can FeNO help guide first-line treatment in suspected asthma?
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| 634 | An uncoordinated effort: A new mechanism of exercise intolerance in fibrotic interstitial lung disease
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| 636 | Surgical treatment of obstructive sleep apnoea in childhood: Lessons for the way forward
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| COMMENTARIES |
| 638 | Commitment to quit is essential for tobacco harm reduction
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| 641 | Artificial intelligence in COPD: Possible applications and future prospects
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| INVITED REVIEW SERIES |
| 643 | Pharmacological treatment of stable chronic obstructive pulmonary disease
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| 652 | Pathophysiology of infection with SARS-CoV-2—What is known and what remains a mystery
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| ORIGINAL ARTICLES |
| Asthma and Allergy |
| 666 | A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial
Lissa Sutherland, Karen Shaw, Clair Parrish, Nicola Singleton, Tricia M McKeever, Iain Stewart, Dominick Shaw, Matthew J Martin, Tim Harrison
10.1111/resp.14055
We conducted a randomized, double-blind placebo-controlled trial and demonstrated that steroid-naïve patients with symptoms suggestive of asthma and a fractional exhaled nitric oxide level ≤ 27 parts per billion (ppb) are unlikely to benefit from treatment with an inhaled corticosteroid over 3 months. |
| Interstitial Lung Disease |
| 673 | Thoracoabdominal asynchrony associates with exercise intolerance in fibrotic interstitial lung diseases
Pauliane Vieira Santana, Leticia Zumpano Cardenas, Jeferson George Ferreira, Carlos Roberto Ribeiro de Carvalho, André Luis Pereira de Albuquerque, Pedro Caruso
10.1111/resp.14064
We assessed respiratory muscle recruitment and coordination in patients with fibrotic interstitial lung disease (f-ILD) during exercise. We found that exercise induced thoracoabdominal asynchrony (TAA) and early recruitment of inspiratory muscles in f-ILD patients. Exercise-induced TAA occurred in f-ILD patients with greater pulmonary restriction and associated with exercise limitation and dyspnoea. |
| 683 | Prevalence and prognostic impact of physical frailty in interstitial lung disease: A prospective cohort study
Mohammed A Malik Farooqi, Sachi O'Hoski, Sarah Goodwin, Nima Makhdami, Afia Aziz, Gerard Cox, Joshua Wald, Christopher J Ryerson, Marla K Beauchamp, Nathan Hambly, Martin Kolb
10.1111/resp.14066
Physical frailty is common in interstitial lung disease (ILD) and is independently associated with increased death after adjusting for age, sex lung function and ILD diagnosis. It represents a potentially modifiable risk factor for mortality that should be assessed in patients with fibrotic ILD. |
| Sleep and Ventilation |
| 690 |
Effect of surgical intervention for mild childhood obstructive sleep apnoea on attention and behavioural outcomes: A randomized controlled study
Chun T Au, Kate C C Chan, Dennis L Y Lee, Natalie Leung, Samuel M W Chow, Judy S Chow, Yun K Wing, Albert M Li
10.1111/resp.14050
This randomized trial confirmed improvements in polysomnographic index and parent-reported symptoms after adenotonsillectomy in pre-pubertal school-aged children with mild obstructive sleep apnoea. However, no improvements in objective attention measures were found, and weight gain and elevated blood pressure were observed after surgery. |
| CONTEMPORARY CONCISE REVIEW |
| 700 | Contemporary Concise Review 2020: Sleep
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| FORUM AND DEBATE |
| Scientific Letter |
| 707 | Delay or avoidance of routine, urgent and emergency medical care due to concerns about COVID-19 in a region with low COVID-19 prevalence: Victoria, Australia
Mark É Czeisler, Jessica L Kennedy, Joshua F Wiley, Elise R Facer-Childs, Rebecca Robbins, Laura K Barger, Charles A Czeisler, Shantha M W Rajaratnam, Mark E Howard
10.1111/resp.14094 |
| Correspondence |
| 713 | Urgent need to define telerehabilitation for respiratory disease
Tristan Bonnevie PT, PhD, Marius Lebret PT, PhD, Zoe McKeough BAppSc(Physio), PhD
10.1111/resp.14069 |
| LETTER FROM ASIA-PACIFIC AND BEYOND |
| 715 | Letter from Greece
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| CORRIGENDUM |
| 718 | CORRIGENDUM
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