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| EDITORIALS |
| 1010 | Decline in respiratory and cardiac admissions during the COVID-19 pandemic: What is the role of common respiratory virus infections?
Chloe I Bloom MBCHb, BSc (Hons), MSc, PhD, Sebastian L Johnston MBBS, PhD
10.1111/resp.14138 |
| 1012 | IL-17A: A promising target in viral lung infections
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| 1014 | Initiating home non-invasive ventilation: How well are we doing?
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| COMMENTARIES |
| 1016 | Mental health among healthcare workers during the COVID-19 pandemic
Natasha Smallwood BMedSci, MBBS, SpecCertPallCare, MSc, FRCP, FRACP, PhD, Karen Willis BA, MA (Hons), GradDipHealthProm, PhD
10.1111/resp.14143 |
| 1018 | Did you smoke? Addressing stigma in lung cancer
Sara McLaughlin-Barrett BNursing, PostGrad Cert Caring for Lung Cancer Patients, Vanessa N Brunelli RN, BN (Hons 1A), DAppSci, PhD
10.1111/resp.14161 |
| 1021 | Behaviour change: The key to implementing evidence on COPD prevention, diagnosis and management
Ian A Yang MBBS (Hons), PhD, FRACP, FAPSR, FThorSoc, Grad Dip Clin Epid, Christine F McDonald AM, MBBS (Hons), PhD, FRACP, FCCP, FThorSoc, Jill J Francis PhD, GDACP, BA, B.Mus
10.1111/resp.14160 |
| 1024 | Antibiotic-resistant bacteria: COVID-19 hasn't made the challenge go away
Grant Waterer MBBS, PhD, Chiagozie Ifeoma Pickens MD, Richard Wunderink MD
10.1111/resp.14166 |
| SYSTEMATIC REVIEW |
| 1027 | Tocilizumab administration for the treatment of hospitalized patients with COVID-19: A systematic review and meta-analysis
Christos Kyriakopoulos, Georgios Ntritsos, Athena Gogali, Haralampos Milionis, Evangelos Evangelou, Konstantinos Kostikas
10.1111/resp.14152
Tocilizumab administration for the treatment of hospitalized patients with COVID-19: A systematic review and meta-analysis |
| ORIGINAL ARTICLES |
| Respiratory Infections |
| 1041 |
Impact of COVID-19 pandemic restrictions on the cardio-respiratory health of New Zealanders
Sarah M Fairweather, Catherina L Chang, Christopher J Mansell, Eskandarain Shafuddin, Robert J Hancox
10.1111/resp.14119
COVID-19 pandemic restrictions in New Zealand led to marked reductions in circulating respiratory viruses and winter infectious respiratory admissions. There was little change in cardiac admissions, suggesting that respiratory viruses play a central role in seasonal respiratory admissions but not the winter peak in heart failure. |
| 1049 | IL-17A is a common and critical driver of impaired lung function and immunopathology induced by influenza virus, rhinovirus and respiratory syncytial virus
Xiaoming Liu, Thi Hiep Nguyen, Leon Sokulsky, Xiang Li, Keilah Garcia Netto, Alan Chen-Yu Hsu, Chi Liu, Karen Laurie, Ian Barr, Hock Tay, Fiona Eyers, Paul S Foster, Ming Yang
10.1111/resp.14141
IL-17A plays a central role in driving the immunopathogenesis of three commonly acquired respiratory viruses by regulating the development and persistence of inflammation, impaired lung function and severity of histopathology. Blockade of IL-17A attenuated these features of disease, identifying its potential as a pivotal therapeutic target for anti-viral immunotherapy. |
| Lung Function |
| 1060 | Associations between respiratory and vascular function in early childhood
Emily J Hemstock, Jingyi Shao, Bing Zhao, Graham L Hall, Amanda J Wheeler, Shyamali C Dharmage, Shannon M Melody, Marita F Dalton, Rachel E Foong, Grant J Williamson, Katherine J Chappell, Michael J Abramson, Kazuaki Negishi, Fay H Johnston, Graeme R Zosky
10.1111/resp.14117
Associations between respiratory and vascular function in early childhood. We found a relationship between peripheral lung stiffness and vascular stiffness in young children. This association was independent of a number of known confounding factors suggesting that this relationship is established in early life and driven by links between these physiological systems and global tissue stiffness. |
| Sleep and Ventilation |
| 1067 | Defining successful non-invasive ventilation initiation: Data from a real-life cohort
Grégoire Jolly, Léa Razakamanantsoa, Emeline Fresnel, Zouhaier Gharsallaoui, Antoine Cuvelier, Maxime Patout
10.1111/resp.14118
Associations between respiratory and vascular function in early childhood. We have shown that, following non-invasive ventilation (NIV) initiation in this cohort, improvement in gas exchange was not correlated with improvement in quality of life. Side effects were common and associated with poorer outcome. Achieving a tidal volume of 7.8 ml/kg of ideal body weight increased the chance of adequate NIV initiation. |
| FORUM AND DEBATE |
| Scientific Letter |
| 1076 | Attenuation of exertional desaturation and preference for interval exercise compared to continuous exercise in people with interstitial lung disease
Leona M Dowman, Anthony K May, Narelle S Cox, Norman R Morris, Atsuhito Nakazawa, Lewan Parker, Janet Bondarenko, Anne E Holland
10.1111/resp.14159 |
| Correspondence |
| 1080 | Respiratory viral infections do not explain the winter peak in heart failure
Catherina L Chang MD, FRACP, Robert J Hancox MD, Chris Mansell MBChB, FRCPA, Sarah M Fairweather BSc, Eskandarain Shafuddin PhD, FRACP
10.1111/resp.14153 |
| LETTERS FROM ASIA-PACIFIC AND BEYOND |
| 1082 | Letter from Trinidad and Tobago: No final battles in the weary war on COVID-19?
Saeed Rashaad Mohammed B.Med.Sci, Trisha Sakhamuri B.Med.Sci, Sateesh Sakhamuri MBBS, DM, FCCP, ATSF, FAPSR, Surujpal Teelucksingh MBBS, FRCP (EDIN), PhD
10.1111/resp.14129 |
| 1085 | Letter from Brazil
Donato da Silva Braz Júnior DPT, Maria Júlia Gonçalves de Mello MD, PhD, Nathália Alves de Barros e Lyra BS, Mirela Muniz Arantes Viana BS, Vinícius Santos Borba BS, Luiz Claudio Santos Thuler MD, PhD, Guilherme Jorge Costa MD, PhD
10.1111/resp.14164 |
