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EDITORIALS |
253 | Recommendations from the Medical Education Editor
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256 | Severe exacerbations and mortality in COPD: Importance of both body and mind
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258 | CT in COPD: To be or not to be
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260 | COVID-19 vaccine-induced immunity: Head-to-head comparison of mRNA (BNT162b2) versus inactivated (CoronaVac) vaccines
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POSITION PAPER |
262 | Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’
Adrian Barnett, Richard Beasley, Catherine Buchan, Jimmy Chien, Claude S Farah, Gregory King, Christine F McDonald, Belinda Miller, Maitri Munsif, Alex Psirides, Lynette Reid, Mary Roberts, Natasha Smallwood, Sheree Smith
10.1111/resp.14218 |
ORIGINAL ARTICLES |
COPD |
277 | The HUNT study: Association of comorbidity clusters with long-term survival and incidence of exacerbation in a population-based Norwegian COPD cohort
Sigrid Anna Aalberg Vikjord, Ben Michael Brumpton, Xiao-Mei Mai, Solfrid Romundstad, Arnulf Langhammer, Lowie Vanfleteren
10.1111/resp.14222
In a chronic obstructive pulmonary disease (COPD) cohort recruited from a general population, we confirmed five distinct comorbidity clusters. Two of these, a psychological and a cachectic cluster, were significantly associated with mortality and the risk of severe COPD exacerbations. |
286 | Chest CT-assessed comorbidities and all-cause mortality risk in COPD patients in the BODE cohort
Ana Ezponda, Ciro Casanova, Miguel Divo, Marta Marín-Oto, Carlos Cabrera, Jose M Marín, Gorka Bastarrika, Víctor Pinto-Plata, Ángela Martin-Palmero, Francesca Polverino, Bartolome R Celli, Juan P de Torres
10.1111/resp.14223
This multicentric study shows that chest computed tomography (CT) to evaluate the presence of 10 comorbidities detects important pathologies not diagnosed in the clinical management of those patients. While emphysema, coronary artery calcification (CAC) and bronchiectasis were the most prevalent CT-detected comorbidities, CAC, bronchiectasis and low Psoas muscle density were independently associated with all-cause mortality. |
Interstitial Lung Disease |
294 | Predictors of mortality in subjects with progressive fibrosing interstitial lung diseases
Kevin K Brown, Yoshikazu Inoue, Kevin R Flaherty, Fernando J Martinez, Vincent Cottin, Francesco Bonella, Stefania Cerri, Sonye K Danoff, Stephane Jouneau, Rainer-Georg Goeldner, Martin Schmidt, Susanne Stowasser, Rozsa Schlenker-Herceg, Athol U Wells
10.1111/resp.14231
We assessed relationships between baseline and time-varying factors and mortality over 52 weeks in 1061 subjects with idiopathic pulmonary fibrosis (IPF) and 663 subjects with other progressive fibrosing interstitial lung diseases (ILDs). Our findings support similarity in the course of IPF and ILD and an association between decline in forced vital capacity and mortality. |
Respiratory Infections |
301 |
Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong
Chris Ka Pun Mok, Carolyn A Cohen, Samuel M S Cheng, Chunke Chen, Kin-On Kwok, Karen Yiu, Tat-On Chan, Maireid Bull, Kwun Cheung Ling, Zixi Dai, Susanna S Ng, Grace Chung-Yan Lui, Chao Wu, Gaya K Amarasinghe, Daisy W Leung, Samuel Yeung Shan Wong, Sophie A Valkenburg, Malik Peiris, David S Hui
10.1111/resp.14191
Through the head-to-head comparison, vaccination with BNT162b2 induces significantly higher levels of SARS-CoV-2-specific binding and neutralizing antibody responses compared to CoronaVac. CoronaVac induces higher CD4+ and CD8+ T-cell responses to the structural protein than BNT162b2. |
LETTERS FROM ASIA-PACIFIC AND BEYOND |
311 |
Leading women pulmonologists in India: Beacons of change
Vijayalakshmi Thanasekaraan MD (General Medicine), Diploma in TB and Chest Diseases, Uma Maheswari Krishnaswamy MD (Internal Medicine), DM (Pulmonary and Critical Care), Fellowship in Sleep Disorders (RCP, UK)
10.1111/resp.14228 |
314 | Letter from Saudi Arabia
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FORUM AND DEBATE |
Correspondence |
316 | Is it time to use HFNC oxygen therapy during exercise in IPF patients?
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318 | Reply
Jumpei Harada, Kazuma Nagata, Takeshi Morimoto, Kentaro Iwata, Atsushi Matsunashi, Yuki Sato, Ryo Tachikawa, Akira Ishikawa, Keisuke Tomii
10.1111/resp.14221 |