| EDITORIALS |
| 402 | Severe asthma treated by bronchial thermoplasty: A success not due to the small airways?
Pascal Chanez MD PhD, Laurie Pahus PharmD PhD, Jeremy Charriot MD, Arnaud Bourdin MD PhD
10.1111/resp.13481 |
| 404 | Molecular breath analysis for IPF: Can we make a few breaths count?
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| 406 | ACCESS ALL AREAS: Electromagnetic navigation and the pulmonologist
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| 408 | Bronchiolitis obliterans syndrome 'endotypes' in haematopoietic stem cell transplantation
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| COMMENTARY |
| 410 | Severe acute respiratory syndrome and other emerging severe respiratory viral infections
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| INVITED REVIEW SERIES |
| Paediatric and Adult Bronchiectasis |
| 413 | Paediatric and adult bronchiectasis: Diagnosis, disease burden and prognosis
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| INVITED REVIEW |
| 423 | Why are people with asthma susceptible to pneumonia? A review of factors related to upper airway bacteria
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| ORIGINAL ARTICLES |
| Asthma and Allergy |
| 431 |
Measuring the effects of bronchial thermoplasty using oscillometry
David Langton, Alvin Ing, Joy Sha, Kim Bennetts, Nicole Hersch, McKinny Kwok, Virginia Plummer, Francis Thien, Claude Farah
10.1111/resp.13439
Oscillometry was used to examine the effects of bronchial thermoplasty on the small airways of 43 patients with severe asthma. No significant effects were demonstrated. |
| Interstitial Lung Disease |
| 437 |
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis
Martin Thomas Gaugg, Anna Engler, Lukas Bregy, Yvonne Nussbaumer-Ochsner, Lara Eiffert, Tobias Bruderer, Renato Zenobi, Pablo Sinues, Malcolm Kohler
10.1111/resp.13465
Collagen-related amino acids are significantly increased in exhaled breath of idiopathic pulmonary fibrosis (IPF) patients compared with healthy controls. The detection of these amino acids using real-time breath analysis results in a good discrimination between the groups, indicating the possibility for a rapid, non-invasive screening for IPF. |
| 445 | Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure – function study
Joseph Jacob, Michael Pienn, Christian Payer, Martin Urschler, Maria Kokosi, Anand Devaraj, Athol U Wells, Horst Olschewski
10.1111/resp.13485
In Idiopathic pulmonary fibrosis (IPF), vessel volume and vessel density link powerfully with forced vital capacity (FVC), total lung capacity (TLC) and composite physiologic index (CPI) but weakly with measures of vasculopathy (diffusion capacity for carbon monoxide (DLCO) and transfer factor for carbon monoxide (KCO)). Vessel volume and heterogeneity are independently linked with DLCO, TLC and CPI. The results reinforce the need for more detailed study of the vasculature in IPF. |
| Interventional Pulmonology |
| 453 | Safety and diagnostic performance of pulmonologists performing electromagnetic guided percutaneous lung biopsy (SPiNperc)
Christopher Mallow, Hans Lee, Catherine Oberg, Jeffrey Thiboutot, Jason Akulian, Allen C Burks, Branden Luna, Sadia Benzaquen, Hitesh Batra, Jose Cardenas-Garcia, Jennifer Toth, Jay Heidecker, Adam Belanger, Jason McClune, Umar Osman, Venkatesh Lakshminarayanan, Nicholas Pastis, Gerard Silvestri, Alexander Chen, Lonny Yarmus
10.1111/resp.13471
Lung cancer screening has led to the discovery of over 1 million pulmonary nodules each year. New technology allows pulmonologists to perform percutaneous lung biopsies using electromagnetic (EM) guided technology. In this retrospective analysis, we demonstrate that EM percutaneous needle biopsy is safe, feasible and provides an acceptable diagnostic yield. See related Editorial |
| Rare Lung Disease |
| 459 | Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome
Wang-Chun Kwok, Bin-Miao Liang, Macy M S Lui, Terence C C Tam, Joycelyn P Y Sim, Eric W C Tse, Anskar Y H Leung, Yok L Kwong, Albert K W Lie, Mary S M Ip, David C L Lam
10.1111/resp.13472
Patients with post-haematopoietic stem cell transplantation (HSCT) bronchiolitis obliterans syndrome (BOS) who manifested initial rapid lung function decline within 3 months of BOS diagnosis had significantly poorer lung function and worse overall survival compared to those with initial gradual decline in lung function after BOS diagnosis. See related Editorial |
| Tuberculosis |
| 467 | Bidirectional association between tuberculosis and sarcoidosis
Sheng-Huei Wang, Chi-Hsiang Chung, Tsai-Wang Huang, Wen-Chiuan Tsai, Chung-Kan Peng, Kun-Lun Huang, Wann-Cherng Perng, Chih-Feng Chian, Wu-Chien Chien, Chih-Hao Shen
10.1111/resp.13482
This bidirectional cohort study strengthens the evidence that tuberculosis (TB) is a risk factor for sarcoidosis. Patients with sarcoidosis showed a higher risk of developing TB within the first year after diagnosis of sarcoidosis. |
| CONTEMPORARY CONCISE REVIEW |
| 475 | Contemporary Concise Review 2018: Lung cancer and pleural disease
Francesca M Conway, Justin L Garner, Christopher M Orton, Karthi Srikanthan, Samuel V Kemp, Pallav L Shah
10.1111/resp.13499 |
| REVIEW |
| 484 | Air pollution in the Asia-Pacific Region: A Joint Asian Pacific Society of Respirology/American Thoracic Society perspective (Republication)
Crystal M North, Mary B Rice, Thomas Ferkol, David Gozal, Christopher Hui, Soon-Hee Jung, Kozo Kuribayashi, Meredith C McCormack, Michiaki Mishima, Yasuo Morimoto, Yuanlin Song, Kevin C Wilson, Woo Jin Kim, Kwun M Fong
10.1111/resp.13531 |
| LETTER FROM ASIA-PACIFIC AND BEYOND |
| 492 | Letter from France: How structures condition outputs
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| CORRESPONDENCE |
| 494 | Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure
Peter H S Sporn MD, S Marina Casalino-Matsuda PhD, Khalilah L Gates MD
10.1111/resp.13522
See Reply |
| 494 | Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure – Reply
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| ERRATUM |
| 496 | Erratum
10.1111/resp.13523 |
