EDITORIALS |
502 | Obesity and the lungs: Not just a crush
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504 | How best to assess cough as an outcome measure
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506 | Azithromycin and ABBA in the chest clinic: 'The winner takes it all...'
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508 | Treatment of interstitial lung disease: Do the ends justify the means?
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510 | Predicting which children have asthma: Are we any closer to finding the Holy Grail?
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INVITED REVIEW SERIES |
Non-invasive ventilation |
512 | Respiratory adjuncts to NIV in neuromuscular disease
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521 | NIV in amyotrophic lateral sclerosis: The 'when' and 'how' of the matter
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INVITED REVIEW |
531 | Endobronchial ultrasound-guided transbronchial needle aspiration in sarcoidosis: Beyond the diagnostic yield
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ORIGINAL ARTICLES |
Asthma and Allergy |
543 | BMI but not central obesity predisposes to airway closure during bronchoconstriction
Ubong Peters, Meenakumari Subramanian, David G Chapman, David A Kaminsky, Charles G Irvin, Robert A Wise, Gwen S Skloot, Jason H T Bates, Anne E Dixon
10.1111/resp.13478
The effect of body mass index (BMI) and waist circumference (WC) on spirometric lung function and airway closure during induced bronchoconstriction was assessed in patients with asthma. WC, but not BMI, was associated with restrictive effects on baseline spirometry. However, during bronchoconstriction, airway closure was associated with increased BMI, rather than WC.
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551 | Development and validation of the COugh Assessment Test (COAT)
Hyeon-Kyoung Koo, Ina Jeong, Joo-Hee Kim, Sung-Kyoung Kim, Jong-Wook Shin, So Young Park, Chin Kook Rhee, Eun Young Choi, Ji-Yong Moon, Yee Hyung Kim, Hyun Lee, Hye Seon Kang, Kyung Hoon Min, Jin Woo Kim, Je Hyeong Kim, Sang Haak Lee, Kwang Ha Yoo, Deog Kyeom Kim, Hyoung Kyu Yoon, Dong-Gyu Kim, Hui Jung Kim, Ki-Suck Jung, Seung Hun Jang, on behalf of the Cough Study Group of the Korean Academy of Tuberculosis and Respiratory Diseases
10.1111/resp.13462
The COugh Assessment Test (COAT) is a simple assessment that has good repeatability, reliability and validity, with clear discriminative properties. The COAT might serve as a useful parameter for the evaluation of chronic cough in clinic and research settings.
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Bronchiectasis |
558 |
Idiopathic chronic productive cough and response to open-label macrolide therapy: An observational study
Matthew J Martin, Helen Lee, Carly Clayton, Kate Pointon, Irshad Soomro, Dominick E Shaw, Tim W Harrison
10.1111/resp.13483
A group of patients with chronic productive cough of unknown cause not adequately described by existing disease labels is described in terms of their physiological, radiological and pathological features. The majority of these patients demonstrated neutrophilic or paucigranulocytic airway inflammation and their symptoms responded well to azithromycin.
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Interstitial Lung Disease |
566 |
Therapeutic burden in interstitial lung disease: Lessons to learn
Yet H Khor, Ian Glaspole, Nicole S L Goh
10.1111/resp.13480
This is the first study providing insights into the significance of therapeutic complexity and polypharmacy in patients with interstitial lung disease (ILD). Patients receiving systemic corticosteroids are at high risk of drug–disease interactions. Additional studies are needed to evaluate the impacts of therapeutic burden on clinical outcomes in patients with ILD.
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Paediatric Lung Disease |
572 | Urine metabolic profiles in paediatric asthma
Jia-Lei Tao, Yan-Zhen Chen, Qi-Gang Dai, Man Tian, Shou-Chuan Wang, Jin-Jun Shan, Jian-Jian Ji, Li-Li Lin, Wei-Wei Li, Bin Yuan
10.1111/resp.13479
We investigated metabolic profiles of paediatric asthma patients to identify asthma-specific biomarkers in urine. A combination of eight metabolites showed excellent discrimination across groups. Enrichment analysis identified complex biological processes associated with immunity, inflammation, oxidative stress and DNA damage. These approaches enabled discrimination between asthma stages and elucidate its mechanisms.
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Sleep and Ventilation |
582 | Pharyngeal distensibility during expiration is an independent predictor of the severity of obstructive sleep apnoea
Ning-Hung Chen, Shih-Wei Lin, Li-Pang Chuang, Peter A Cistulli, Meng-Jer Hsieh, Kuo-Chin Kao, Yu-Fang Liao, Li-Fu Li, Cheng-Ta Yang
10.1111/resp.13474
We have devised an image-based method that can rapidly assess obstructive sleep apnoea (OSA) severity in awake patients. We have shown that, in awake patients, airway distensibility/collapsibility during expiration, but not inspiration, is related to the severity of OSA. Airway distensibility is an independent risk factor for OSA, but not related to anatomical changes in the tongue and soft palate.
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POSITION STATEMENT |
590 | Emerging respiratory infections threatening public health in the Asia-Pacific region: A position paper of the Asian Pacific Society of Respirology
Sunghoon Park, Ji Young Park, Yuanlin Song, Soon Hin How, Ki-Suck Jung, on behalf of the Respiratory Infections Assembly of the APSR
10.1111/resp.13558 |
CONTEMPORARY CONCISE REVIEW |
598 | Contemporary Concise Review 2018: Respiratory infections and tuberculosis
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LETTER FROM ASIA-PACIFIC AND BEYOND |
605 | Letter from Italy
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CORRESPONDENCE |
607 | Airway distensibility: Bringing physiology to the bedside
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607 | Airway distensibility: Bringing physiology to the bedside – Reply
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