| EDITORIALS |
| 966 | GLUCOLD, eosinophils and chronic obstructive pulmonary disease
|
| 968 | Managing disease behaviour: A team approach
|
| 970 | Does virtual bronchoscopic navigation improve the diagnostic yield of transbronchial biopsy?
|
| 972 | Does CPAP for obstructive sleep apnoea improve asthma control?
|
| 974 | Repurposing metformin to prevent and treat tuberculosis
|
| COMMENTARY |
| 976 | Melbourne epidemic thunderstorm asthma event 2016: Lessons learnt from the perfect storm
|
| INVITED REVIEW SERIES |
| Tuberculosis Updates 2018 |
| 978 | New drugs and regimens for tuberculosis
|
| Molecular Techniques for Respiratory Diseases |
| 991 | How do new molecular tools apply to my clinical practice?
Ian A Yang MBBS (Hons), PhD, FRACP, FAPSR, FThorSoc, Grad Dip Clin Epid, Yuben Moodley MBChB FCP FRACP MD PhDabstart
13361'>10.1111/resp.13361 |
| 993 | Proteomics: Clinical and research applications in respiratory diseases
|
| Paediatric and Adult Bronchiectasis |
| 1004 | Moving forward: Bronchiectasis and chronic suppurative lung disease in children and adults in the 21st century
Adam T Hill MBChB, MD, FRCPEd; Anne B Chang MBBS, PhD, FRACP, FAPSR, FThorSoc, FAHMS
10.1111/resp.13396 |
| 1006 | Bronchiectasis: Treatment decisions for pulmonary exacerbations and their prevention
|
| ORIGINAL ARTICLES |
| COPD |
| 1023 |
Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD
Floor J Hartjes, Judith M Vonk, Alen Faiz, Pieter S Hiemstra, Thér`se S Lapperre, Huib A M Kerstjens, Dirkje S Postma, Maarten van den Berge, and the Groningen & Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) Study Group
10.1111/resp.13312
Blood eosinophils, in contrast to neutrophils, reflect eosinophils in sputum, biopsies and bronchoalveolar lavage (BAL), in inhaled corticosteroids (ICS)-naive COPD patients. However, both baseline eosinophils and neutrophils, whether measured in blood, sputum, biopsies and BAL, insufficiently predict lung function response to ICS in COPD over a period of 6-30 months. |
| Interstitial Lung Disease |
| 1032 | Prognostic factors and disease behaviour of pathologically proven fibrotic non-specific interstitial pneumonia
Hideaki Yamakawa, Hideya Kitamura, Tamiko Takemura, Satoshi Ikeda, Akimasa Sekine, Tomohisa Baba, Tae Iwasawa, Eri Hagiwara, Shinji Sato, Takashi Ogura
10.1111/resp.13313
Non-specific interstitial pneumonia (NSIP) has heterogeneous characteristics in terms of background, disease behaviour and prognosis. Some patients with idiopathic fibrotic NSIP with or without interstitial pneumonia with autoimmune features (IPAF) showed progressive disease despite therapy. |
| 1041 |
Multidimensional improvement in connective tissue disease-associated interstitial lung disease: Two courses of pulse dose methylprednisolone followed by low-dose prednisone and tacrolimus
Yasuhiko Yamano, Hiroyuki Taniguchi, Yasuhiro Kondoh, Masahiko Ando, Kensuke Kataoka, Taiki Furukawa, Takeshi Johkoh, Junya Fukuoka, Koji Sakamoto, Yoshinori Hasegawa
10.1111/resp.13365
Two courses of pulse dose methylprednisolone therapy followed by 1 year of tacrolimus combination therapy with corticosteroids was well tolerated and improved not only lung physiology but also exercise capacity, exercise oxygen desaturation and patient-reported outcomes (PRO) such as dyspnoea and health-related quality of life (HRQoL). |
| Lung cancer |
| 1049 | Virtual bronchoscopic navigation as an aid to CT-guided transbronchial biopsy improves the diagnostic yield for small peripheral pulmonary lesions
Akane Kato, Masanori Yasuo, Yayoi Tokoro, Takashi Kobayashi, Takashi Ichiyama, Kazunari Tateishi, Atsuhito Ushiki, Kazuhisa Urushihata, Hiroshi Yamamoto, Masayuki Hanaoka
10.1111/resp.13377
Computed tomography (CT)-guided transbronchial biopsy (CT-TBB) is one of the several procedures used to diagnose small peripheral pulmonary lesions (PPL), although its diagnostic yield is unsatisfying. We now report that a combined approach in which virtual bronchoscopic navigation (VBN) is used to assist CT-TBB improves the diagnostic yield for small PPL. |
| Sleep and Ventilation |
| 1055 | Continuous positive airway pressure for obstructive sleep apnoea does not improve asthma control
Susanna S S Ng, Tat-On Chan, Kin-Wang To, Ken K P Chan, Jenny Ngai, Wing-Ho Yip, Rachel L P Lo, Fanny W S Ko, David S C Hui
10.1111/resp.13363
In this randomized controlled trial involving patients with nocturnal asthma and snoring despite taking moderate-to-high-dose inhaled corticosteroid and long-acting bronchodilators, continuous positive airway pressure (CPAP) therapy for 3?months did not improve asthma control but led to better asthma-related quality of life and vitality than those on conservative treatment. |
| Tuberculosis |
| 1063 | Metformin is associated with a lower risk of active tuberculosis in patients with type 2 diabetes
Shang-Yi Lin, Hung-Pin Tu, Po-Liang Lu, Tun-Chieh Chen, Wen-Hung Wang, Inn-Wen Chong, Yen-Hsu Chen
10.1111/resp.13338
This retrospective, propensity score-matched cohort study demonstrated that the risk of active tuberculosis (TB) is higher in the type 2 diabetes mellitus population. However, the use of metformin is associated with a decreased risk of active TB in this population. |
| LETTER FROM ASIA-PACIFIC REGION |
| 1074 | Letter from India
|
| CORRESPONDENCES |
| 1076 | Red blood cell transfusion in acute pulmonary embolism
|
| 1076 | Red blood cell transfusion in acute pulmonary embolism - Reply
Christopher Wong MBBS, Leonard Kritharides PhD, Austin Chin Chwan Ng MMed
10.1111/resp.13408 |
