| EDITORIALS |
| 294 | Ambulatory oxygen delivery – an answer: But what is the question?
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| 296 | CPAP treatment for asthma? A question worth pursuing further
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| 298 | Is there a common pattern in physical activity levels comparing diverse chronic airway diseases?
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| 300 | Lumpers versus splitters: What to do with suspected idiopathic pulmonary fibrosis?
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| 302 | Treating moderate – severe obstructive sleep apnoea for cardiovascular health: Is what stake the stakeholder holds important?
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| COMMENTARY |
| 304 | Time to FOCUS on oral corticosteroid stewardship in asthma management
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| INVITED REVIEW SERIES |
| Non-Invasive Ventilation |
| 306 | Non-invasive ventilation: Inspiring clinical practice
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| 308 | Benefits of non-invasive ventilation in acute hypercapnic respiratory failure
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| 318 | High-intensity non-invasive ventilation in stable hypercapnic COPD: Evidence of efficacy and practical advice
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| SYSTEMATIC REVIEW |
| 329 | Comparison of continuous flow versus demand oxygen delivery systems in patients with COPD: A systematic review and meta-analysis
Rainer Gloeckl, Christian Osadnik, Lisa Bies, Daniela Leitl, Andreas-Rembert Koczulla, Klaus Kenn
10.1111/resp.13457 |
| ORIGINAL ARTICLES |
| Asthma and Allergy |
| 338 | Effect of CPAP on airway reactivity and airway inflammation in children with moderate – severe asthma
Eduardo Praca, Hasnaa Jalou, Nadia Krupp, Angela Delecaris, Joseph Hatch, James Slaven, Susan J Gunst, Robert S Tepper
10.1111/resp.13441
We compared 4 weeks of nocturnal continuous positive airway pressure (CPAP) versus sham to suppress airway reactivity and inflammation in children with moderate – severe asthma. There were no significant differences between treatments. The treatment effect in children with moderate – severe asthma was smaller than previously reported in adults with mild well-controlled asthma. |
| Critical Care |
| 345 | Angiopoietin-2 as a predictor of acute kidney injury in critically ill patients and association with ARDS
Camila Barbosa, Araújo Fernanda Macedo de Oliveira Neves, Daniele Ferreira de Freitas, Bianca Fernandes Távora Arruda, Leonardo José Monteiro de Macêdo Filho, Vivian Brito Salles, Gdayllon Cavalcante Meneses, Alice Maria Costa Martins, Alexandre Braga Libório
10.1111/resp.13464
Angiopoietin-2 (AGPT2) is a known acute respiratory distress syndrome (ARDS) biomarker and its use has been recently proposed for acute kidney injury (AKI). We demonstrated that AGPT2 is associated with AKI only in patients with or developing ARDS. Adding AGPT2 to a clinical model results in significant improvement in the capacity to predict severe AKI in patients with ARDS. |
| COPD |
| 352 | Physical activity associates with disease characteristics of severe asthma, bronchiectasis and COPD
Laura Cordova-Rivera, Peter G Gibson, Paul A Gardiner, Vanessa M McDonald
10.1111/resp.13428
This is the first study characterizing and comparing the prevalence of physical activity (PA) between a severe asthma, bronchiectasis, chronic obstructive pulmonary disease (COPD) and a control population; and in testing the associations of key treatable and shared disease characteristics with the level of PA in obstructive airway diseases. |
| Interstitial Lung Disease |
| 361 |
Implications of the diagnostic criteria of idiopathic pulmonary fibrosis in clinical practice: Analysis from the Australian Idiopathic Pulmonary Fibrosis Registry
Helen E Jo, Ian Glaspole, Nicole Goh, Peter M A Hopkins, Yuben Moodley, Paul N Reynolds, Sally Chapman, Eugene Haydn Walters, Christopher Zappala, Heather Allan, Sacha Macansh, Christopher Grainge, Gregory J Keir, Andrew Hayen, Douglas Henderson, Sonja Klebe, Stefan B Heinze, Anne Miller, Hannah C Rouse, Edwina Duhig, Wendy A Cooper, Annabelle M Mahar, Samantha Ellis, Samuel R McCormack, Bernard Ng, David B Godbolt, Tamera J Corte
10.1111/resp.13427
In clinical practice, physicians may assign a diagnosis of idiopathic pulmonary fibrosis (IPF) in patients who are sufficiently similar in their presentation to IPF but who do not strictly fulfil IPF diagnostic criteria. Our study shows that these patients demonstrate identical disease progression and survival to those who fulfil diagnostic criteria. |
| Interventional Pulmonology |
| 369 | Radiofrequency spectral analysis of EBUS for peripheral pulmonary lesions
Kei Morikawa, Noriaki Kurimoto, Takeo Inoue, Teruomi Miyazawa, Masamichi Mineshita
10.1111/resp.13443
Endobronchial ultrasonography (EBUS) is widely used for its high diagnostic rate. This is the first report to investigate the quantitative assessment of EBUS radiofrequency (RF) for peripheral pulmonary lesions. RF analysis might be capable of distinguishing pathological heterogeneity of the lesion better than distinguishing benign and malignant, which can contain various pathological subtypes. |
| Sleep and Ventilation |
| 376 |
A consensus opinion amongst stakeholders as to benefits of obstructive sleep apnoea treatment for cardiovascular health
Shane A Landry, Siobhan Banks, Peter A Cistulli, Garun S Hamilton, Laure Héraud, Kristina Kairaitis, Steven Lubke, Sutapa Mukherjee, Teanau Roebuck, Joesph Soda, Darren Umbers, Shantha M W Rajaratnam, Darren Mansfield
10.1111/resp.13413
Commissioned by the Australasian Sleep Association and the Sleep Health Foundation, this statement draws on a panel composed of key sleep medicine stakeholders, including clinicians, researchers, technologists, as well as industry and community groups, to provide consensus of opinion as to the cardiovascular benefits of treating moderate – severe obstructive sleep apnoea. |
| CONTEMPORARY CONCISE REVIEW |
| 382 | Contemporary Concise Review 2018: Bronchiectasis
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| LETTER FROM ASIA-PACIFIC AND BEYOND |
| 390 | Letter from South Africa
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| CORRESPONDENCES |
| 392 | Infection risks for patients from healthcare workers with cystic fibrosis
Mark Thomas MBChB, MD, FRACP; Warwick Bagg MBBCh, MD, FRACP; John Kolbe MBBS, FRACP
10.1111/resp.13487 |
| 393 | Infection risks for patients from healthcare workers with cystic fibrosis - Reply
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