| Case series |
One-year clinical experience on the use of Nintedanib in systemic sclerosis
Luca Magnani, Amelia Spinella, Sofia Testoni, Federica Lumetti, Chiara Scelfo, Lucia Dardani, Gianluigi Bajocchi, Enrico Clini, Carlo Salvarani, Dilia Giuggioli
DOI: 10.1002/rcr2.1120
We reviewed eleven patients with Systemic Sclerosis-related ILD who were referred to our Scleroderma Unit from January 2020 to January 2021 and who started Nintedanib. |
Variable radiographic and histologic presentations of amiodarone-related interstitial lung disease and the importance of avoiding re-exposure
I-Lin Tsai, Li-Ting Huang, Yu-Ting Yu, Chung-Ta Lee, Tang-Hsiu Huang
DOI: 10.1002/rcr2.1165
Amiodarone-related interstitial lung disease may exhibit variable clinical, radiographic, and histologic presentations. Prompt discontinuation and avoiding re-exposure of the agent is important to prevent the progression and recurrence of the interstitial lung disease. |
| Case reports |
Massive pulmonary embolism led to cardiac arrest two days after thoracoscopy in a young male with pleural tuberculosis
Wael Kanjo, Shahem Abbarh, Amina Bougaila, Nagham Sadik, Mhd Baraa Habib
DOI: 10.1002/rcr2.1069
We describe a fatal case of a 30-year-old previously healthy male with pleural tuberculosis who developed a massive pulmonary embolism with subsequent cardiac arrest after a diagnostic medical thoracoscopy. Computed tomography pulmonary angiogram showed major right pulmonary embolism. Unfortunately, the patient passed away despite resuscitation and extensive organ support in the intensive care unit. This case highlights the thrombotic risk in this population group in order to avoid such devastating complications. |
Ultrasound-controlled transthoracic true-cut needle biopsy in pulmonary nodular amyloidosis
Teodora Z Mihalova, Silviya S Ivanova, Evgeni V Mekov, Yordanka Т Yamakova, Rosen E Petkov
DOI: 10.1002/rcr2.1142
The current case report presents a 59-year-old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Preliminary diagnoses for possible granulomatosis (tuberculosis) or pulmonary metastatic dissemination of a neoplastic process were made. An ultrasound-controlled transthoracic true-cut needle biopsy of a subpleural lesion was performed, confirming the diagnosis of ‘pulmonary nodular amyloidosis’. |
Combined treatment with beaded EWS, Gore-tex patch and N-butyl-2-cyanoacrylate for bronchial fistula: The novel “sandwich method”
Marino Yamamoto, Masaya Tamura, Ryohei Miyazaki, Hironobu Okada
DOI: 10.1002/rcr2.1153
In this report, we describe, for the first time, a novel method for closing bronchopleural fistula (BPF) using an endobronchial Watanabe spigot (EWS), polyglycolic acid (PGA) sheet and N-butyl-2-cyanoacrylate (NBCA). We named this method the “sandwich method.” |
PD-L1-negative non-small cell lung cancer harbouring a rare BRAF mutation with successful treatment of first-line pembrolizumab plus chemotherapy: A case report and review the literature
Kien Hung Do, Tai Van Nguyen, Phuong Nguyen Thi Bich, Gia Hoang Nguyen, Chu Van Nguyen
DOI: 10.1002/rcr2.1155
We document the case of a 63-year-old patient with NSCLC harbouring a rare BRAF E501Q mutation, who had a prolonged response to immunotherapy combined with chemotherapy in Vietnam. |
Intrapleural therapy for pleural infection from bronchopleural fistula in an adult with hyper-IgE syndrome
Sam Faber, Andrew McLean-Tooke, Yi Jin Kuok, Y C Gary Lee
DOI: 10.1002/rcr2.1156
An adult with hyper-IgE syndrome presented with a large hydropneumothorax secondary to bronchopleural fistula and pleural infection. Alongside standard care, he received two doses of low-dose intrapleural therapy (1 mg tissue plasminogen activator and 5 mg deoxyribonuclease), which allowed complete evacuation of his residual loculated pleural fluid, aided resolution of his infection without provoking a significant air leak and avoided the need for surgery. |
Severe asthma remaining well-controlled after mepolizumab discontinuation: A case report and literature review
Takahiro Matsuyama, Yuya Tomioka, Hiromi Matsuyama, Yusuke Kamenohara, Kengo Tanigawa, Yoichi Dotake, Yoko Hagihara, Koichi Takagi, Kentaro Machida, Hiromasa Inoue
DOI: 10.1002/rcr2.1158
Mepolizumab, a humanized anti-IL-5 monoclonal antibody used for severe asthma, results in reduced asthma exacerbations, improved lung function, reduced oral corticosteroid use, and improved quality of life. But little is known about the effects of withdrawal after long-term treatment. Here, we report a case of a patient with asthma, well-controlled without exacerbation after withdrawal of mepolizumab. |
Pulmonary alveolar proteinosis after lung transplantation: Two case reports and literature review
Shinichi Kawana, Kentaroh Miyoshi, Shin Tanaka, Seiichiro Sugimoto, Dai Shimizu, Kei Matsubara, Mikio Okazaki, Noboru Hattori, Shinichi Toyooka
DOI: 10.1002/rcr2.1160
Pulmonary alveolar proteinosis (PAP) affecting transplanted lungs is not well recognized. Herein, we report two cases of PAP after lung transplantation (LTx) and their management. Transplant physicians should be aware of this rare complication to avoid misconducting immunosuppressive management. |
A 92-year-old patient with thoracic empyema successfully treated by CT-guided insertion of a pigtail catheter
Kohei Fujita, Masataka Hirai, Zentaro Saito, Takanori Ito, Takuma Imakita, Issei Oi, Osamu Kanai, Hiromasa Tachibana, Tadashi Mio
DOI: 10.1002/rcr2.1162
We present a case report of a 92-year-old patient with thoracic empyema, who was successfully treated via CT-guided insertion of a pigtail catheter. We believe that this educational case serves as a testament to the fact that even the most aged patients can be successfully treated with resourcefulness. |
Management of alveolar-pleural fistula secondary to invasive pulmonary aspergillosis with bronchial occlusion using a combination of Endobronchial Watanabe Spigot and N-butyl-2-cyanoacrylate: A case report
Shinya Tsukamoto, Kazuma Nagata, Keisuke Tomii
DOI: 10.1002/rcr2.1163
Alveolar-pleural and bronchopleural fistulas that do not improve with thoracic drainage in patients who are unfit for surgery can be successfully managed by endobronchial occlusion and pleurodesis. However, the strategy to be followed in case of failure in conventional conservative management is unclear. We report a case of alveolar-pleural fistula managed by bronchial occlusion using a combination of Endobronchial Watanabe Spigot and N-butyl-2-cyanoacrylate. |
A hole lot of trouble: Severe bilateral anastomotic dehiscence following bilateral single sequential lung transplant
Cameron White, Alice Stuart, Marshall Plit, Monique Malouf, Paul Lilburn
DOI: 10.1002/rcr2.1164
In this case, report we describe a 22-year-old female who developed significant bilateral anastomotic dehiscence with severe ischaemia following a bilateral single sequential lung transplant (BSSLTx) to treat neonatal bronchiolitis obliterans. |
Rapid onset of effect of benralizumab in a severe eosinophilic and allergic asthma patient with allergic bronchopulmonary aspergillosis
Arvindran Alaga, Khairil Ashraff, Nurul Hana Din Khan
DOI: 10.1002/rcr2.1167
Case report of a 65-year-old woman with combined severe eosinophilic and allergic asthma, who was later diagnosed with concomitant allergic bronchopulmonary aspergillosis. Benralizumab demonstrated a significant role in reducing the exacerbation rate and oral corticosteroid use in this patient, as well as improving lung function, asthma control, and quality of life measures. |
Resection of tracheal mucosa-associated lymphoid tissue (MALT) lymphoma by bronchoscopic high-frequency electrosurgical snare: Case report
Satoshi Nakamura, Yasuyuki Kishikawa, Ai Koike, Yuriko Takahata, Yuki Okamatsu, Akitaka Fujita, Masako Arimura-Omori, Taishi Harada
DOI: 10.1002/rcr2.1168
We herein report a case of mucosa-associated lymphoid tissue (MALT) lymphoma with tracheal metastasis from the left lower jaw that was resected with a bronchoscopic high-frequency electrosurgical snare. |
A case of eosinophilic pneumonia induced by lettuce
Reina Sekiya, Tatsuya Nagano, Tatsuya Moriyama, Aki Kawaguchi, Takafumi Fukui, Chihiro Mimura, Yohei Kimura, Hisashi Ohnishi, Yoshikazu Kotani, Yoshihiro Nishimura
DOI: 10.1002/rcr2.1169
We report a first case of eosinophilic pneumonia induced by lettuce in a lettuce farmer. |
| Clinical images |
Azygos vein thrombosis despite rivaroxaban therapy in a patient with breast cancer: A rare entity
Guliz Degirmenci, Celal Satici
DOI: 10.1002/rcr2.1154
Azygos vein thrombosis (AVT) is an extremely rare type of venous thromboembolism. It is commonly associated with predisposing factors such as azygous vein aneurysm and malignancy including cholangiocarcinoma and renal cell carcinoma. Here we report a rare case of AVT associated with metastatic breast cancer. |
Furious lung abscess due to Parvimonas micra
Shinnosuke Fukushima, Hideharu Hagiya, Hiromichi Naito, Fumio Otsuka
DOI: 10.1002/rcr2.1161
We present a case of lung abscess due to Parvimonas micra in a 57 year old woman who did not respond to antibiotics and needed surgical resection, indicating the high virulence of this bacteria. |
Intrapleural findings of pulmonary light-chain deposition disease
Takashi Yamashita, Kensuke Takei, Yuta Matsubayashi, Kiyomichi Mizuno, Katsuyuki Asai
DOI: 10.1002/rcr2.1166
Light-chain deposition disease is accompanied not only by characteristic CT findings but also by characteristic gross findings of the visceral pleura. Medical thoracoscopy could diagnose LCDD by the findings of the thoracic cavity. |
