Respirology Case Reorts

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November 2018
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Case Series
Management of rifampicin mono-resistant tuberculosis in Queensland, Australia: a retrospective case series
Justine Gibson, Ellen Donnan, Geoffrey Eather
DOI: 10.1002/rcr2.366

Exogenous lipoid pneumonia is an important cause of interstitial lung disease that often goes unrecognized.

Case Reports
Pulmonary hernia: Case report and review of the literature
Chiara Scelfo, Chiara Longo, Marina Aiello, Giuseppina Bertorelli, Ernesto Crisafulli, Alfredo Chetta
DOI: 10.1002/rcr2.354

We report a case of pulmonary hernia secondary to thoracic-surgical intervention. The clinical course was characterized by a clinical latency before the onset. The patient showed risk factors consisting in obesity and in poliomyelitis infection sequelae.

Transient elevation of squamous cell carcinoma antigen levels with influenza virus infection
Atsushi Sano
DOI: 10.1002/rcr2.362

Squamous cell carcinoma antigen (SCCA) is a glycoprotein that is used as a tumor marker of squamous cell carcinoma of the neck, esophagus, lung, and cervix uteri. However, it is a non-specific test and SCCA levels are also elevated due to other conditions. Herein, we report a case of SCCA elevation due to influenza B infection in a patient with a history of surgery for lung cancer.

Nintedanib prevented fibrosis progression and lung cancer growth in idiopathic pulmonary fibrosis
Kentaro Fukunaga, Shinya Yokoe, Satoru Kawashima, Yasuki Uchida, Hiroaki Nakagawa, Yasutaka Nakano
DOI: 10.1002/rcr2.363

Nintedanib prevented progression of IPF and the associated squamous cell carcinoma simultaneously as a result of its diverse mechanisms of action.

Congenital cystic adenomatoid malformation in adults detected after infection
Hiroyuki Kagawa, Keisuke Miki, Mari Miki, Koji Urasaki, Seigo Kitada
DOI: 10.1002/rcr2.364

Congenital cystic adenomatoid malformation (CCAM) is a benign congenital tumour in which a part of the lung becomes polycystic. Although CCAM in adults is very rare, it should be considered in the differential diagnosis of cases with repeated pneumonia due to suspected congenital cystic disease. CCAM is better detectable with chest computed tomography and requires active surgical treatment.

Spontaneous fracture of indwelling pleural catheter
Lokesh Yagnik, Ranjan Shrestha
DOI: 10.1002/rcr2.365

We report the first case of spontaneous fracture of indwelling permanent pleural catheter (IPCs) used for the management of symptomatic malignant pleural effusion. Unexpected damage during insertion, loss of material integrity, and/or external shearing forces are suggested causes in the absence of any evidence of a manufacturing defect. Successful retrieval with medical pleuroscopy is feasible.

Mycoplasma hominis empyema following caesarean section
Masatoshi Yamazoe, Hiromi Tomioka, Shuji Yamashita, Kazusa Egami, Kouji Oh
DOI: 10.1002/rcr2.367

We herein report the first case of M. hominis empyema following caesarean section.

Persistent air leak successfully treated with endobronchial valves and digital drainage system
Thomas James Altree, Hubertus Jersmann, Phan Nguyen
DOI: 10.1002/rcr2.368

A 62-year old man with pneumothorax and persistent air leak was treated with a combination of endobronchial valves and the use of a digital chest drainage system. In cases of persistent air leak, digital drainage systems can play an important role in decision-making regarding endobronchial valve placement, and timing of intercostal catheter removal, based on objective air leak flow measurements. These benefits are in addition to a digital drainage system's ability to provide suction at a regulated pressure.

Multi-drug-resistant tuberculosis with galaxy and cluster signs on high-resolution computed tomography
Keitaro Nakamoto, Yuka Sasaki, Hiroyuki Kokuto, Masao Okumura, Takashi Yoshiyama, Hajime Goto
DOI: 10.1002/rcr2.369

Galaxy and cluster signs are considered useful signs indicative of pulmonary sarcoidosis. However, pulmonary tuberculosis may also show these findings. We report a patient with multidrug-resistant tuberculosis with galaxy and cluster signs requiring differentiation from sarcoidosis on high-resolution computed tomography.

Recurrent respiratory papillomatosis: the role of cidofovir
Mai Ngoc Tran, Lauren Galt, Farzad Bashirzadeh
DOI: 10.1002/rcr2.371

Recurrent respiratory papillomatosis (RRP) is a difficult entity to treat. A robust evidence-based efficacious treatment regime to achieve remission for this debilitating condition remains elusive. This case study describes the use of intralesional cidofovir in successfully prolonging symptom remission of RRP.

Effective combined therapy with ramucirumab for advanced pulmonary pleomorphic carcinoma
Naoya Nishioka, Yoshiko Kaneko, Tadaaki Yamada, Naoko Okura, Soichi Hirai, Koichi Takayama
DOI: 10.1002/rcr2.372

Pulmonary pleomorphic carcinoma (PPC) is a rare disease with a poor prognosis. Most patients with PPC are refractory to chemotherapy, whereas good responses to platinum-based chemotherapy in combination with the anti-angiogenesis agent bevacizumab have been reported. Here, we report an effective combined therapy with ramucirumab for patients with PPC.

A case of lung tumorlets secondary to pulmonary hypoplasia with recurrent haemoptysis
Kyoko Yagyu, Atsushi Miyamoto, Haruhiko Matsushita, Akira Okimora
DOI: 10.1002/rcr2.373

Most patients with lung tumorlets are usually asymptomatic, and most diagnoses are incidental findings during microscopic lung examinations at autopsy or after excision of a tissue lesion. We recently encountered a patient with pulmonary tumorlet with pulmonary hypoplasia requiring emergency surgery due to recurring hemoptysis progressing over a course of 5 years. We believe that the hemoptysis in our patient was possibly caused by the lung tumorlets secondary to lobar hypoplasia.

Clinical Images
Metastatic pulmonary malignant melanoma showing a ring-shaped and halo signs
Toshihiro Masuda, Toshihiro Shirai, Mika Saigusa, Kazuhiro Asada, Hiroyuki Muro
DOI: 10.1002/rcr2.370

Classically, metastatic tumours are solid, multiple, well-circumscribed, and rarely cavitary. This rare case of metastatic pulmonary malignant melanoma showed a ring-shaped ground-glass opacity and then the halo sign depending on the disease progression.

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