| Case Reports |
Switching from omalizumab to mepolizumab therapy improved extra-pulmonary abdominal and cutaneous vasculitis symptoms in a patient with eosinophilic granulomatosis with polyangiitis
Yu-Hsuan Chen, Ping-Hung Kuo
DOI: 10.1002/rcr.878
We report the clinical benefits after switching from omalizumab to mepolizumab in an anti-neutrophil cytoplasmic antibodies-negative eosinophilic granulomatosis with polyangiitis patient on her abdominal and cutaneous manifestations. |
Two cases of cryptogenic organizing pneumonia masquerading as tuberculosis (TB) in a TB endemic area
Mohamed Faisal Abdul Hamid, Sai Banu Selvarajah, Nik Nuratiqah, Ng Boon Hau, Andrea Yu-Lin Ban
DOI: 10.1002/rcr.883
We report two patients with cryptogenic organizing pneumonia (OP) mimicking tuberculosis (TB). These cases highlight the rare presentation of OP and serves as a reminder that patients tested negative for TB, despite typical history and chest imaging findings, warrant further investigations as many diseases may mimic TB and vice versa. |
Cinematic CT as a valuable protocol for severe ECAC
Daniel Hernandez-Rojas MD, David Abia-Trujillo MB, MD, Carlos Rojas MD, Alejandra Yu Lee-Mateus MD, Rocio Castillo-Larios MD, Sai Priyanka Pulipaka MD, Sebastian Fernandez-Bussy MD
DOI: 10.1002/rcr.884
We report a case with suspected expiratory central airway collapse (ECAC), where initial workup with standard forced expiratory computed tomography (CT) could not detect expiratory collapse. Given the high index of suspicion for ECAC, the patient underwent dynamic bronchoscopy confirming the diagnosis. Subsequently, the implementation of a novel CT protocol, dynamic forced expiratory (cinematic), which comprises detailed, consecutive helical imaging of the central airway throughout the entire respiratory cycle could also confirm severe ECAC as proven by dynamic bronchoscopy. |
Inflammatory myofibroblastic tumour of the lung: Case report and review of the literature
Sonila Boriçi, Marjeta Tanka, Luljeta Serbo
DOI: 10.1002/rcr.885
Inflammatory myofibroblastic tumour of the lung is a rarely encountered lesion. Although it is commonly seen in children, the number of childhood cases in the literature is limited. It has a dual nature: it may behave as an inflammatory lesion or a tumour with the capacity for recidivism and metastasis. So, the syndrome requires careful follow-up. |
Chronic pulmonary aspergillosis in a patient with hyper-IgE syndrome
Keisuke Kasuga, Keitaro Nakamoto, Kazuyuki Doi, Nozomi Kurokawa, Takeshi Saraya, Haruyuki Ishii
DOI: 10.1002/rcr.887
Hyperimmunoglobulin E (IgE) syndrome (HIES) is rare disease characterized by recurrent infections, eczema and increased serum level of IgE. Chronic pulmonary aspergillosis (CPA) is a chronic progressive infectious disease common in patients with underlying pulmonary diseases, but there are few reports of complications due to HIES. We report a case of HIES comorbid with CPA in a teenage male. |
Good's syndrome presenting with CMV pneumonitis and oesophageal candidiasis: A case report
Chin Tong Kwok, Yiu Cheong Yeung
DOI: 10.1002/rcr.888
Thymomas are often associated with paraneoplastic disorders. Patients with thymoma presenting with opportunistic infections should be screened for hypogammaglobulinaemia. We describe a case of Good's syndrome presenting with cytomegalovirus pneumonitis and oesophageal candidiasis, and an incidental diagnosis of renal cell carcinoma. |
A case of effective intravenous methylprednisolone pulse therapy against severe COVID-19 infection after arteriovenous graft surgery
Sokichi Kamata, Souhei Hamanaka, Jin Tsukamoto, Teppei Tsuchimoto, Kiyohiro Fujiwara, Mikio Okamura
DOI: 10.1002/rcr.889
COVID-19 infections in patients suffering from end-stage renal disease (ESRD) are more likely to become severe than in other patients, with a high mortality rate. Among the therapeutic agents known to be effective, only corticosteroids can be used in patients suffering from ESRD, significantly limiting treatment options. We report a case of ESRD in which COVID-19 infection immediately followed arteriovenous graft surgery. Although the respiratory condition deteriorated following dexamethasone administration, requiring invasive mechanical ventilation, pulse therapy was successful. |
Recurrent COVID-19 infection in a case of rituximab-induced hypogammaglobulinaemia
Jefferson Daniel, Balamugesh Thangakunam, Barney Thomas Jesudason Isaac, Mahesh Moorthy, Devasahayam Jesudas Christopher
DOI: 10.1002/rcr.891
Recurrent COVID-19 should be considered while managing post-COVID complications. Patients with immunodeficiency are at an increased risk of COVID-19 re-infection. |
Cryobiopsy for Pneumocystis jirovecii pneumonia secondary to adult T-cell lymphoma/leukaemia
Hiroshi Kobe, Kenki Saito, Machiko Arita, Tadashi Ishida
DOI: 10.1002/rcr.893
A case of transbronchial lung cryobiopsy (TBLC) performed on a lung lesion in a patient with adult T-cell lymphoma/leukaemia (ATLL) diagnosed with Pneumocystis jirovecii pneumonia is presented. This is an important report that shows the usefulness of TBLC in differentiating pulmonary lesions in ATLL. |
Association of COVID-19 antigenicity with the development of antineutrophilic cytoplasmic antibody vasculitis
Jamie R Felzer, Delvise T Fogwe, Shaher Samrah, Clement J Michet Jr, Ulrich Specks, Misbah Baqir, Aahd F Kubbara
DOI: 10.1002/rcr.894
We present two cases of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV): one that developed after coronavirus disease 2019 (COVID-19) infection presenting as diffuse alveolar haemorrhage and another that developed shortly after vaccination, presenting as granulomatous pulmonary nodules. Both patients improved with supportive care and immunosuppressive therapies. This adverse event appears to be a very rare complication of COVID-19 infection or vaccination. Early diagnosis of AAV is important because immunosuppressive therapy may improve patient outcomes. |
| Clinical images |
COVID-19-induced adult multisystem inflammatory syndrome and fatal acute limb ischaemia
Hiroshi Kobe, Akihiro Ito, Tadashi Ishida
DOI: 10.1002/rcr.886
A case of coronavirus disease 2019 (COVID-19)-induced adult multisystem inflammatory syndrome and fatal acute limb ischaemia is presented. |
A rare case of urachal carcinoma with multiple lung metastasis that required differentiation from primary lung carcinoma
Kentaro Suzuki, Yoshiro Kai, Masayuki Matsuda, Kazuhide Horimoto, Kazunori Iwai, Masato Takano, Masahito Yoshii, Shigeo Muro
DOI: 10.1002/rcr.890
Urachal cancer, a rare malignancy, constitutes <1% of all bladder cancers. The prognosis of metastatic urachal cancer is extremely poor. Cases of distant metastasis without local recurrence alone are relatively rare. We describe a case of multiple metastatic lung cancer from urachal carcinoma that required differentiation from primary lung cancer. |
Congenital pulmonary airway malformation: A rare diagnosis in adulthood
Raquel Viana, Lina Carvalho, Cláudia Santos
DOI: 10.1002/rcr.895
This paper consists of a clinical image of a complex developmental anomaly that is usually diagnosed prenatally or during childhood. Its detection in adult life is very rare, as happened in the present case. |
| Clinical video |
Nasal myiasis under direct bronchoscopic visualization
Ahel El Haj Chehade, Jordan Metcalf, Blake Jacobs
DOI: 10.1002/rcr.892
This video shows a case of nasal myiasis under fibreoptic bronchoscopic visualization in a patient admitted with septic shock and metastatic prostate cancer. |
