Respirology Case Reorts

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January 2019
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Case Series
The significance of non-occupational asbestos exposure in women with mesothelioma
Nonhlanhla Tlotleng, Kerry Sidwell Wilson Nisha, Naicker, Coenraad F N Koegelenberg, David Rees, James Ian Phillips
DOI: 10.1002/rcr2.386

In this report we highlight three cases of mesothelioma in women with diverse environmental exposures.

Evaluation of expiratory capacity with severe asthma following bronchial thermoplasty
Satoru Ishii, Motoyasu Iikura, Yukiko Shimoda, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama
DOI: 10.1002/rcr2.387

Bronchial thermoplasty (BT) is a bronchoscopic treatment for severe asthma using thermal energy to reduce the amount of smooth muscle in the bronchial wall. In the present study, expiratory computed tomography (CT) imaging was performed before and after BT, and changes in expiratory lung capacity were measured. Use of CT for evaluation of expiratory volume may be a method for assessing the effectiveness of BT.

Case Reports
Transbronchial lung cryobiopsy: a novel confirmatory tool to diagnose asbestos-related pulmonary fibrosis
Marta Zajaczkowska, Anthony Johnson, Luis Gallur, Joo Shin, Christopher Henderson, Jonathan Williamson
DOI: 10.1002/rcr2.380

Transbronchial cryobiopsy appears to be an effective way of obtaining parenchymal lung samples of sufficient size to diagnose asbestosis when clinical uncertainty exists.

Pleuritis with pleural effusion due to a Bacillus megaterium infection
Ernesto Crisafulli, Ilaria Aredano, Ilaria Valzano, Barbara Burgazzi, Francesco Andrani, Alfredo Chetta
DOI: 10.1002/rcr2.381

We report a case of a hospitalized male for a pleuritis with pleural effusion caused by a Bacillus megaterium infection, a Gram-positive, aerobic, spore forming and rod-shaped bacterium. To our knowledge, our case report is the first evidence of pleuritis due to B. megaterium. In the literature, up to now B. megaterium infection has only been reported to involve eye, skin and brain.

Aorto-pleural fistula successfully treated by one-lung ventilation and Endobronchial Watanabe Spigots
Takunori Hozumi, Koichiro Kajiura, Kei Nakamura, Haruki Taniguchi, Takao Goto, Michitaka Nasu
DOI: 10.1002/rcr2.382

Aorto-pleural fistula (APF) is a rare, potentially fatal condition that should be immediately treated by an endovascular or surgical approach. In this case, we treated APF by bronchial occlusion with Endobronchial Watanabe Spigots (EWS) after controlling massive bleeding by one-lung ventilation.

Gastric perforation related to concurrent use of nintedanib and ramucirumab
Saeko Takahashi, Saori Murata, Yudai Yoshino, Yosuke Kobayashi, Morio Nakamura
DOI: 10.1002/rcr2.383

We report the first case of 70-year-old man taking nintedanib for his progressive idiopathic pulmonary fibrosis (IPF) and treated with ramucirumab plus docetaxel as a seventh line therapy for his pulmonary adenocarcinoma. On day15 of chemotherapy treatment cycle2, after taking nintedanib for nine days, he developed gastric perforation.

Diffuse pulmonary lymphangiomatosis treated with bevacizumab
Ernest Onyeforo, Adrian Barnett, Debbie Zagami, David Deller, Iain Feather
DOI: 10.1002/rcr2.384

Diffuse pulmonary lymphangiomatosis (DPL) is a rare disease caused by uncontrolled lymphatic vessel proliferation resulting in respiratory dysfunction. We believe this is the first case of DPL to report lung function improvement (forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and DLCO) following bevacizumab therapy.

Effectiveness of benralizumab for allergic and eosinophilic predominant asthma following negative initial results with omalizumab
Daisuke Minami, Hiroe Kayatani, Ken Sato, Keiichi Fujiwara, Takuo Shibayama
DOI: 10.1002/rcr2.388

We present a patient with both allergic and eosinophilic predominant asthma whose asthma symptom control and sinusitis were improved by benralizumab following negative initial results with omalizumab.

Clinical Image
Autoimmune pulmonary alveolar proteinosis presenting peripheral ground-glass opacities
Keishi Sugino, Masahiro Ando, Kiyoshi Mori, Eiyasu Tsuboi
DOI: 10.1002/rcr2.385

Autoimmune pulmonary alveolar proteinosis should be considered in the differential diagnosis of peripheral ground glass opacities.

Index

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