Respirology Case Reorts

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February 2019
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Case Series
Management of malignant carinal involvement using 'side-by-side' method of bilateral self-expandable metallic stents
Takayuki Takeda, Hideki Itano, Ryo Wakasa, Masahiko Saitoh, Sorou Takeda
DOI: 10.1002/rcr2.396

Central airway obstruction (CAO) is critical and life-threatening for cancer patients and is categorized as an oncological emergency that requires urgent intervention. Malignant carinal involvement is considered one of the most difficult situations among CAO, which is usually treated by rigid bronchoscopic intervention under general anaesthesia. The application of 'side-by-side' method of bilateral self-expandable metallic stents has been reported in the management of malignant carinal involvement. This technique is useful in the treatment of patients of poor performance status who would not tolerate general anaesthesia. We retrospectively analysed six patients who were treated by this method in terms of effectiveness, tolerance, and safety of the procedure.

Case Reports
Coexistent sarcoidosis and lymphangioleiomyomatosis in a patient with cystic lung disease
Sarah Cullivan, Peter De La Harpe Golden, Deirdre Doyle, Kishore Kumar Doddakula, Louise Burke, Desmond Michael Murphy
DOI: 10.1002/rcr2.389

This is an interesting case of coexistent lymphangioleiomyomatosis and pulmonary sarcoidosis in a 45-year-old lady with cystic lung disease. This case highlights important clinical, radiological, and physiological features of both conditions and suggests a potential shared disease mechanism.

Pleural anthracosis presenting with massive effusion: a rare entity
Rayhan Amiseno, Andrea Yu-Lin Ban, Noraidah Masir, Lizawati Rasul Hamidi, Mohamed Faisal Abdul Hamid
DOI: 10.1002/rcr2.390

This article is about a patient with recurrent admissions for symptomatic pleural effusion. Diffuse hyperpigmentation in both parietal and visceral pleural was visualised, and biopsy demonstrated granuloma with foreign body giant cell (anthracosis). This case highlights the unusual presentation of pleural anthracosis with pleural effusion.

Porous diaphragm syndrome with recurrent thymoma
Takayo Ota, Yoshikazu Hasegawa, Takafumi Okabe, Akira Okimura, Masahiro Fukuoka
DOI: 10.1002/rcr2.391

Porous diaphragm syndrome is a defect in the diaphragm in which substances pass from the peritoneal to the pleural cavity. Increasing intra-abdominal pressure by ascites and diaphragmatic thinning due to malnutrition by malignancies resulted in the formation of an artificial hole.

A case of Aspergillus and Nocardia infections after bronchial thermoplasty
Sachi Matsubayashi, Motoyasu Iikura, Takanori Numata, Shinyu Izumi, Haruhito Sugiyama
DOI: 10.1002/rcr2.392

Bronchial thermoplasty (BT) is a bronchoscopic procedure that uses thermal energy to reduce airway smooth muscle mass for treating uncontrolled severe asthma. Bronchial oedema and radiologic changes are generally known as the major complications of BT, but infections have rarely been reported. We describe a case of fungal and bacterial infections that developed after BT.

A 17-year-old woman with a solitary, mixed squamous cell and glandular papilloma of the bronchus
Takeshi Saraya, Masachika Fujiwara, Hirokazu Kimura, Hidefumi Takei, Hajime Takizawa

Solitary endobronchial papillomas are extremely rare, accounting for only 0.38% of all lung tumours and approximately 7% of all benign epithelial and mesenchymal lung tumours. Here, we present an unexpected case of mixed papilloma in the youngest known patient to date who suffered from chest pain and bloody sputum.

A symptomatic anterior mediastinal mass with a simultaneous Haemophilus influenzae infection
Hui Zen Hee, Chun-Ku Chen, Yi-Chen Yeh, Chien-Sheng Huang
DOI: 10.1002/rcr2.394

We describe a rare case of unanticipatedly delayed complete resection of a symptomatic teratoma with simultaneous Hemophilus influenza infection, followed by extended rupture into the pleural, lung and bronchus. The clinical presentation, microbiology and radiology features leads to an impression of lung abscess until it was proved otherwise pathologically.

Lung spindle cell carcinoma harbouring a constitutively active epidermal growth factor receptor mutation
Hiroaki Ikushima, Toshio Sakatani, Yoshio Masuda, Teppei Morikawa, Kazuhiro Usui
DOI: 10.1002/rcr2.395

Lung spindle cell carcinoma is a rare lung tumour with a poor prognosis, and its standard therapy has not been established. Furthermore, little work has been performed on the genetic characteristics of lung spindle cell carcinomas. Here, we report the first case of lung spindle cell carcinoma with an epidermal growth factor receptor mutation. The patient received gefitinib as first-line therapy.

Anti-interleukin 5 antibody is effective for not only severe asthma and eosinophilic pneumonia but also eosinophilic bronchiolitis
Fuminori Tomyo, Naoya Sugimoto, Masashi Kawamoto, Hiroyuki Nagase, Masao Yamaguchi, Ken Ohta
DOI: 10.1002/rcr2.397

There have been a few case reports of eosinophilic bronchiolitis that is characterized by radiographic findings showing diffuse bronchiolitis plus massive accumulation of eosinophils in the airways. Systemic steroid therapy has been suggested to be effective for this disorder, although the precise pathogenesis in unknown. Here, we report a case of severe asthma complicated with eosinophilic pneumonia and eosinophilic bronchiolitis, all of which were alleviated by anti-interleukin 5 (IL-5) antibody.

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