| Case Reports |
Widespread pulmonary invasion by malignant pleural mesothelioma: an important diagnostic consideration
Mia MacMillan, Bapti Roy, Sally McLaren, Anna K Nowak, Rajesh Thomas, Y C Gary Lee DOI: 10.1002/rcr2.675
We report a rare case of early and extensive pulmonary invasion of malignant pleural mesothelioma (MPM) first presenting with hydropneumothorax. She developed widespread and rapidly progressive FDG-avid pulmonary infiltrates. Bronchoalveolar lavage (BAL) and sputum contained mesothelioma cells. The patient deteriorated rapidly with progressive mediastinal and contralateral MPM involvement and died one month later. This case highlights the importance of including tumour invasion as a differential diagnosis of non-resolving pulmonary infiltrates in patients with MPM. |
Severe pulmonary alveolar proteinosis with respiratory failure treated by intrapulmonary percussive ventilation
Takahiro Tashiro, Yusuke Tomita, Megumi Inaba, Kumiko Hayashi, Naomi Hirata, Takuro Sakagami DOI: 10.1002/rcr2.676
We report the first case of severe autoimmune pulmonary alveolar proteinosis (aPAP) with progressive respiratory failure successfully treated by intrapulmonary percussive ventilation (IPV) therapy for six months. |
Organizing pneumonia associated with T-cell lymphoma
Chrystal Chan, Andrei D Fagarasanu, Andre Reid, Daniel C Sadowski, Ashley-Mae E Gillson DOI: 10.1002/rcr2.677
We report a rare case of organizing pneumonia (OP) associated with T-cell lymphoma without prior anticancer therapy. OP could represent a syndrome of T-cell dysfunction or develop as a direct reaction to malignant infiltration of the lung. In patients with atypical presentations, exclusion of an alternate diagnosis must be pursued using surgical lung biopsy, wherever possible. |
Polymyxin B haemoperfusion treatment for respiratory failure and hyperferritinaemia due to COVID-19
Mayuko Ishiwari, Yuki Togashi, Hiroyuki Takoi, Ryota Kikuchi, Yuta Kono, Shinji Abe DOI: 10.1002/rcr2.679
We report the first case of coronavirus disease 2019 (COVID-19)-induced hyperferritinaemia and severe respiratory failure successfully treated by polymyxin B-immobilized fibre column direct haemoperfusion (PMX-DHP) therapy. |
Paraneoplastic acute fibrinous and organizing pneumonia from lymphoma completely responding to bendamustine-rituximab
Thomas Crowhurst, Pratyush Giri, Caroline Smith, Phan Nguyen, Paul Reynolds DOI: 10.1002/rcr2.681
Acute fibrinous and organizing pneumonia (AFOP) is a rare histopathological pattern of lung injury characterized by fibrin deposition in alveolar spaces. There is no proven treatment but multiple reports describe response to corticosteroids. We report a compelling instance of paraneoplastic AFOP completely responding to chemotherapy for lymphoma with very limited use of corticosteroids. |
Hot tub lung machine
Matthew Corbitt, David Deller DOI: 10.1002/rcr2.682
Hot tub lung (HTL) is a pulmonary disease where a hypersensitivity pneumonitis is caused by exposure and inhalation of aerosolized non-tuberculous mycobacteria (NTM) traditionally from hot water steam. We present, to our knowledge, the only case of HTL occurring from an indoor swimming pool affecting five members of a family, in which one member was not a resident of the household. |
Acute eosinophilic pneumonia accompanied with COVID-19: a case report
Koutaro Murao, Atsushi Saito, Koji Kuronuma, Yoshihiro Fujiya, Satoshi Takahashi, Hirofumi Chiba DOI: 10.1002/rcr2.683
We report a case of acute eosinophilic pneumonia (AEP) triggered by coronavirus disease 2019 (COVID-19) infection. This case suggests the importance of considering the complications of AEP when treating patients with COVID-19 infection. |
Conservative management of airway tear as a complication of silicone endobronchial stenting in bronchomalacia secondary to endobronchial tuberculosis
Nai-Chien Huan, Khai Lip Ng, Mona Zaria Nasaruddin, Noorul Afidza Muhammad, Ummi Nadira Daut, Jamalul Azizi Abdul Rahaman DOI: 10.1002/rcr2.684
We report two patients, both with bronchomalacia due to endobronchial tuberculosis (EBTB), who unfortunately developed bronchial tear related to silicone endobronchial stenting. Both patients were successfully managed conservatively without needing emergency open surgery. This case report highlights the current gap in knowledge regarding (1) optimal management and role of silicone airway stents among patients with bronchomalacia secondary to EBTB (B-EBTB) and (2) whether stent-related complication rates are higher among those with B-EBTB. |
Atezolizumab-induced fulminant type 1 diabetes mellitus occurring four months after treatment cessation
Toshihiko Nishioki, Motoyasu Kato, Shunichi Kataoka, Keita Miura, Tetsutaro Nagaoka, Kazuhisa Takahashi DOI: 10.1002/rcr2.685
We present a case of atezolizumab-induced fulminant type 1 diabetes mellitus (F1DM) that occurred four months after withdrawal of the drug in a 73-year-old Japanese woman highlighting the need for clinicians to closely and continuously monitor the development of immune-related adverse events, including F1DM, irrespective of the number of treatment cycles or the interval after the last immune checkpoint inhibitor cycle. |
| Clinical Image |
Pulmonary lipiodol embolism following transcatheter arterial chemoembolization
Tomohiro Moriya, Naoki Kawakami, Yoko Wakai, Hiroaki Saito, Kazuhito Saito DOI: 10.1002/rcr2.678
One of the complications of transcatheter arterial chemoembolization (TACE) is pulmonary embolism. We present the computed tomography findings of pulmonary embolism in a 70-year-old patient who underwent TACE for recurrent hepatocellular carcinoma. |
