Respirology Case Reorts

Divyansh Bajaj, Nevins Todd, Rydhwana Hossain, Karan Mahajan, Whitney Burrows, Ashutosh Sachdeva
DOI: 10.1002/rcr2.409

We report an unusual case of organizing pneumonia occurring as a consequence of obstruction due to a carcinoid tumour and its complete resolution by bronchoscopic relief of obstruction without the need for steroid therapy.

Jasleen Kaur Pannu, Otis Bryant Rickman, Robert James Lentz, Joyce Evelyn Johnson, Fabien Maldonado
DOI: 10.1002/rcr2.410

Persistent pulmonary opacities associated with respiratory symptoms that progress despite medical treatment present a diagnostic dilemma for pulmonologists. We describe the case of a 37-year-old woman presenting with progressive fatigue, shortness of breath, and weight loss over six months with a progressively worsening right basilar infiltrate on chest imaging in spite of antibacterial therapy. Transbronchial cryobiopsy was used to establish the diagnosis after a bronchoscopy with traditional forceps biopsies was non-diagnostic. This case demonstrates the value of cryobiopsy as a second-line strategy for pulmonary infiltrates when aetiology remains unclear after less invasive testing.

Kana Ohashi, Rintaro Nishimura, Shunsuke Sugimoto, Seiichiro Sakao, Nobuhiro Tanabe, Koichiro Tatsumi
DOI: 10.1002/rcr2.411

Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare plasma cell disease. Patients with POEMS syndrome are considered to be at a high risk of developing pulmonary hypertension (PH). Here, we report the effectiveness of the vasodilators, sildenafil and macitentan, in a patient with PH associated with POEMS.

Toshio Kato, Satoru Ito, Toyonori Tsuzuki, Daisuke Watanabe, Akihito Kubo, Etsuro Yamaguchi
DOI: 10.1002/rcr2.412

Antibodies to transcriptional intermediary factor-1γ (TIF-1γ) are strongly associated with malignancy in patients with dermatomyositis. Anti-TIF-1γ antibodies are a relatively low risk for interstitial lung disease. We report the case of a 68-year-old female with small cell lung cancer and interstitial pneumonia who was diagnosed first with dermatomyositis positive for serum anti-TIF-1γ antibodies.

Shinichi Sasaki, Motoyasu Kato, Kota Nakamura, Yukiko Namba, Osamu Nagashima, Kazuhisa Takahashi
DOI: 10.1002/rcr2.413

After approximately 1 year of the minocycline monotherapy, nearly all skin sarcoidosis lesions resolved with only light residual scars, despite the poor efficacy of the monotherapy for pulmonary sarcoidosis. Minocycline monotherapy appears to be an effective treatment modality for skin sarcoidosis.

Pei Sze Carmen Tan, Ruad Perera
DOI: 10.1002/rcr2.414

With over 150 species, non-tuberculous mycobacteria are increasingly recognized to be important human pathogens that pose diagnostic and management challenges. We report a rare case of cervical lymphadenitis and pulmonary disease caused by Mycobacterium paraffinicum.

Ming-Tsung Chen, Shih-Chun Lee, Chun-Chi Lu, Chen-Liang Tsai
DOI: 10.1002/rcr2.416

The most frequent presentation of Castleman's disease (CD) is a solitary mediastinal mass. We reported a patient with a history of heavy smoking with particular image features of CD, which presented as mediastinal lymphadenopathy and peribronchovascular interstitial thickening mimicking lung cancer or sarcoidosis initially.

Sumit Chatterji, Efrat Ofek, Tiberiu Shulimzon
DOI: 10.1002/rcr2.415

Rare endobronchial angioleiomyoma causes central airway obstruction and respiratory failure. Clinical management includes flexible bronchoscopy and successful cryoextraction of tumour.