| EDITORIALS |
| 404 | Physical activity and health of adults with cystic fibrosis
Craig A Williams |
| 406 | New targeted therapies in the treatment of pulmonary arterial hypertension: getting to the heart of the problem
Philip Marino |
| 408 | Analyses of abdominal fat and sleep apnea
Kazuo Chin |
| INVITED REVIEW SERIES |
| Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes |
| 410 | Asthma–COPD overlap syndrome (ACOS): A diagnostic challenge
Nguyen Van Tho, Hye Yun Park & Yasutaka Nakano |
| 419 | Changing physical activity and sedentary behaviour in people with COPD
Vinicius Cavalheri, Leon Straker, Daniel F Gucciardi, Paul A Gardiner & Kylie Hill |
| Idiopathic Interstitial Pneumonia |
| 427 | Idiopathic pulmonary fibrosis: Diagnosis, epidemiology and natural history
Giacomo Sgalla, Alice Biffi & Luca Richeldi |
| INVITED REVIEW |
| 438 | Airway epithelial repair in health and disease: Orchestrator or simply a player?
Thomas Iosifidis, Luke W Garratt, Deirdre R Coombe, Darryl A Knight, Stephen M Stick & Anthony Kicic |
| REVIEW |
| 449 | Increasing awareness of sex differences in airway diseases
Deepa Raghavan & Raksha Jain |
| ORIGINAL ARTICLES |
| Asthma and Allergy |
| 460 |
Absence of airway inflammation in a large proportion of adolescents with asthma
Collin R Brooks, Christine J van Dalen, Angela Zacharasiewicz, Jodie L Simpson, Jacquie L Harper, Graham Le Gros, Peter G Gibson, Neil Pearce & Jeroen Douwes |
| 467 | Neutrophil extracellular traps are associated with inflammation in chronic airway disease
Thomas K Wright, Peter G Gibson, Jodie L Simpson, Vanessa M McDonald, Lisa G Wood & Katherine J Baines |
| COPD |
| 476 | Inspiratory capacity-to-total lung capacity ratio and dyspnoea predict exercise capacity decline in COPD
Maria A Ramon, Jaume Ferrer, Elena Gimeno-Santos, David Donaire-Gonzalez, Esther Rodríguez, Eva Balcells, Jordi de Batlle, Marta Benet, Stefano Guerra, Jaume Sauleda, Antoni Ferrer, Eva Farrero, Joaquim Gea, Joan A Barberà, Alvar Agustí, Robert Rodriguez-Roisin, Josep M Antó, Judith Garcia-Aymerich & PAC-COPD Study Group |
| 483 | Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD
Robbert C Maatman, Martijn A Spruit, Paula P van Melick, Jos P I Peeters, Erica P A Rutten, Lowie E G W Vanfleteren, Emiel F M Wouters & Frits M E Franssen |
| 489 | Readmissions following an initial hospitalization by COPD exacerbation in Spain from 2006 to 2012
Javier de Miguel-Díez, Rodrigo Jiménez-García, Valentín Hernández-Barrera, Pilar Carrasco-Garrido, Luis Puente Maestu, Laura Ramírez García & Ana López de Andrés |
| 497 | (Cost-)effectiveness of self-treatment of exacerbations in patients with COPD: 2 years follow-up of a RCT
Marlies Zwerink, Huib AM Kerstjens, Job van der Palen, Paul van der Valk, Marjolein Brusse-Keizer, Gerhard Zielhuis & Tanja Effing |
| 504 | Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients
Shakti Dhar Shukla, Hans Konrad Muller, Roger Latham, Sukhwinder Singh Sohal & Eugene Haydn Walters |
| Cystic Fibrosis |
| 511 | Physical activity participation by adults with cystic fibrosis: An observational study
Narelle S Cox, Jennifer A Alison, Brenda M Button, John W Wilson, Judith M Morton & Anne E Holland |
| Lung Cancer |
| 519 | Relationship between circulating tumour cell count and prognosis following chemotherapy in patients with advanced non-small-cell lung cancer
Zixuan Zhang, Yi Xiao, Jing Zhao, Minjiang Chen, Yan Xu, Wei Zhong, Jia Xing & Mengzhao Wang |
| Pulmonary Vascular Disease |
| 526 | BMPR2 gene delivery reduces mutation-related PAH and counteracts TGF-β-mediated pulmonary cell signalling
Feng Feng, Rebecca L Harper & Paul N Reynolds |
| Sleep and Ventilation |
| 533 |
Mesenteric fat thickness is associated with metabolic syndrome independently of Apnoea–Hypopnoea Index in subjects with obstructive sleep apnoea
Kin Hung Liu, Winnie C W Chu, Kin Wang To, Fanny W S Ko, Susanna S S Ng, Jenny C L Ngai, Ka Pang Chan, Wing Ho Yip, Anil T Ahuja & David S C Hui |
| 541 | Role of nasal positive end expiratory pressure valve as an alternative treatment for obstructive sleep apnoea in Chinese patients
Kin Wang To, Tat O Chan, Susana Ng, Jenny Ngai & David SC Hui |
| 546 | Comparison of continuous positive airway pressure and bosentan effect in mildly hypertensive patients with obstructive sleep apnoea: A randomized controlled pilot study
Marie Joyeux-Faure, Ingrid Jullian-Desayes, Jean-Louis Pepin, Jean-Luc Cracowski, Jean-Philippe Baguet, Renaud Tamisier, Patrick Levy, Diane Godin-Ribuot & Sandrine H Launois |
| SCIENTIFIC LETTER |
| 553 | Middle-aged to elderly women have a higher asymptomatic infection rate with Mycobacterium avium complex, regardless of body habitus
Tomoyasu Nishimura, Yukiko Fujita-Suzuki, Masaaki Mori, Stephen M Carpenter, Hiroshi Fujiwara, Yoshifumi Uwamino, Eiko Tamizu, Ikuya Yano, Hiroshi Kawabe & Naoki Hasegawa |
| YEAR IN REVIEW |
| 556 | Year in review 2015: Interstitial lung disease, pulmonary vascular disease, pulmonary function, sleep and ventilation, cystic fibrosis and paediatric lung disease
Helen E Jo, Tamera J Corte, Stephen J Wort, Neil D Eves, Amanda Piper & Claire Wainwright |
| ERRATUM |
| 567 | Erratum
This article corrects: Molecular targeted therapy in the treatment of advanced stage non-small cell lung cancer (NSCLC)
Vol. 20, Issue 3, 370–378, 17 FEB 2015 |
