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EDITORIALS |
464 | Silicosis: An ancient disease in need of a dose of modern medicine
Ryan Hoy MBBS, FRACP, MOccEnvHlth; Daniel C Chambers MBBS, MRCP, FRACP, MD
10.1111/resp.13766 |
466 | Time to embrace POCUS as part of the bedside diagnosis of respiratory diseases
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468 | Community-acquired pneumonia due to drug-resistant Enterobacteriaceae: A global perspective
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COMMENTARIES |
470 | Oxygen therapy for pulmonary arterial hypertension: We need to rethink and investigate
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472 | Efforts to control air pollution in the Asia-Pacific region
Yasuo Morimoto MD, PhD; Hena Khatun MBBS, MD; Kwok Sang Wilson Yee MD; Agus Dwi Susanto MD, PhD; Jun-Pyo Myong MD, PhD; Joven Jeremius Tanchuco MD, MHA; Chau-Chyun Sheu MD; Ngo Quy Chau MD, PhD; Arata Azuma MD, PhD
10.1111/resp.13800 |
INVITED REVIEW SERIES |
New frontiers in sleep-disordered breathing |
475 | A review of approaches for analysing obstructive sleep apnoea-related patterns in pulse oximetry data
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486 | Big Data in sleep apnoea: Opportunities and challenges
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INVITED REVIEW |
495 | Health impacts of bushfire smoke exposure in Australia
Clare M Walter, Elena K Schneider-Futschik, Luke D Knibbs, Louis B Irving
10.1111/resp.13798 |
ORIGINAL ARTICLES |
Asthma and Allergy |
502 | Alternaria induces airway epithelial cytokine expression independent of protease-activated receptor
Michael Daines, Lingxiang Zhu, Rhea Pereira, Xu Zhou, Cheryl Bondy, Barry M Pryor, Jin Zhou, Yin Chen
10.1111/resp.13675
Protease-activated receptor 2 (PAR2)-mediated signalling pathway has been implicated in most of the biological activities induced by Alternaria (Alt), an allergen associated with allergic rhinitis and bronchial asthma. Using both in vivo and in vitro models, we have demonstrated that Alt-induced airway inflammation and epithelial cytokine expression were independent of PAR2 signalling. |
Environmental and Occupational Lung Disease |
511 | miRNA sequencing reveals miRNA-4508 from peripheral blood lymphocytes as potential diagnostic biomarker for silica-related pulmonary fibrosis: A multistage study
Minjie Chu, Shuangshuang Wu, Wei Wang, Liping Mao, Yuhui Yu, Liying Jiang, Weiyan Yuan, Mingjiong Zhang, Lingli Sang, Qiqing Huang, Tian Tian, Lei Han, Xun Zhuang, Zuo-Feng Zhang, Jianqing Wu
10.1111/resp.13714
RNA sequencing screening and two independent validation studies consistently revealed that the expression of miRNA-4508 in peripheral blood lymphocytes was significantly lower in silica-related pulmonary fibrosis (SPF) cases than in healthy controls. Receiver operating characteristic analysis showed that miRNA-4508 could distinguish SPF cases from healthy controls with high sensitivity and specificity. |
518 |
Artificial stone-associated silicosis in China: A prospective comparison with natural stone-associated silicosis
Na Wu. Changjiang Xue. Shiwen Yu. Qiao Ye
10.1111/resp.13744
High silica content of artificial stone and uncontrolled dry cutting and grinding presents as a high risk of developing accelerated silicosis. Compared to natural stone-associated silicosis, artificial stone-associated silicosis was characterized by short latency, rapid radiological progression, accelerated decline in lung function and high mortality in this study.
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Interstitial Lung Disease |
525 |
Acute exacerbations of fibrotic interstitial lung diseases
Atsushi Suzuki, Yasuhiro Kondoh, Kevin K Brown, Takeshi Johkoh, Kensuke Kataoka, Junya Fukuoka, Tomoki Kimura, Toshiaki Matsuda, Toshiki Yokoyama, Jun Fukihara, Masahiko Ando, Tomonori Tanaka, Naozumi Hashimoto, Koji Sakamoto, Yoshinori Hasegawa
10.1111/resp.13682
This study reveals that all forms of fibrotic interstitial lung diseases (FILD) are at risk of acute exacerbations (AE) and have similar outcomes to AE of idiopathic pulmonary fibrosis (AE-IPF). Clinicians are recommended to consider all forms of FILD to be at risk of AE.
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Lung Cancer |
535 | Relevance of lung ultrasound in the diagnostic algorithm of respiratory diseases in a real-life setting: A multicentre prospective study
Luca Rinaldi, Stefania Milione, Maria Chiara, Fascione Pia, Clara Pafundi, Concetta Altruda, Mafalda Di Caterino, Lucio Monaco, Alfonso Reginelli, Fabio Perrotta, Giovanni Porta, Mario Venafro, Carlo Acierno, Davide Mastrocinque, Mauro Giordano, Andrea Bianco, Ferdinando Carlo, Sasso Luigi, Elio Adinolfi
10.1111/resp.13659
Lung ultrasound (LUS) provided a useful diagnostic workup of respiratory disease, either by directly identifying pathological findings or by detecting indirect signs of illness, as in lung cancer. Overall, LUS was not inferior to chest radiography and routine use in medical wards or in emergency department settings is beneficial. |
Respiratory Infections |
543 | Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia
David Villafuerte, Stefano Aliberti, Nilam J Soni, Paola Faverio, Pedro J Marcos, Richard G Wunderink, Alejandro Rodriguez, Oriol Sibila, Francisco Sanz, Ignacio Martin-Loeches, Francesco Menzella, Luis F Reyes, Mateja Jankovic, Marc Spielmanns, Marcos I Restrepo, GLIMP Investigators
10.1111/resp.13663
Hospitalized adults with community-acquired pneumonia (CAP) have low prevalence of Enterobacteriaceae (EB, 6%) and multidrug-resistant (MDR)-EB (1.2%), respectively. Specific risk factors, such as prior extended-spectrum beta-lactamase infection and being underweight, should raise the clinical suspicion for EB and MDR-EB in patients hospitalized with CAP. |
CONTEMPORARY CONCISE REVIEW |
552 | Contemporary Concise Review 2019: Sleep and ventilation
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LETTER FROM ASIA-PACIFIC AND BEYOND |
559 | Letter from Belgium
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