No. 118 (May 2019)
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Vietnam 2019

Abstracts are now being accepted for the 2019 Congress to be held in Hanoi, Vietnam, 14-17 November 2019, and online registration will be open soon.

Keep checking apsr2019.com regularly for updates.

Vietnam 2019 abstract submission guide

You can submit your abstract through Online Submission. Deadline for submission: 23:59 Vietnam time (UTC +7) on 15 July 2019.

  • There is no limitation on how many abstracts an author may submit.
  • Abstracts must be submitted in English.
  • Duplicate abstracts will not be accepted.
  • Abstracts must be submitted online. Submissions via fax, email, post, etc., will NOT be considered.
  • It is the responsibility of the presenting author and submitting author to ensure that all authors have given their consent to be listed on the submitted abstract.
  • Authors must declare that the material in the presentation is original, and declare that the material will not be published in any publication or presented elsewhere before the APSR Congress 2019.
  • Abstracts supported in whole or in part by tobacco or tobacco related industry will not be accepted. Authors are required to complete a Declaration of Interest.
  • The Abstract Title must be UPPERCASE and a maximum of 25 words.
  • The Abstract Body must be a maximum of 300 words. (title, author information, tables and images are excluded from the 300-word count).
  • An abstract must have the sub-headings: Background and Aims, Methods, Results and Conclusions.
  • Authors must choose one category from the following:
    • Clinical Respiratory Medicine
    • Cell and Molecular Biology
    • Clinical Allergy and Immunology
    • Environmental & Occupational Health and Epidemiology
    • Respiratory Infections (non-tuberculous)
    • Tuberculosis
    • COPD
    • Lung Cancer
    • Asthma
    • Respiratory Neurobiology and Sleep
    • Critical Care Medicine
    • Bronchoscopy and Interventional Techniques
    • Paediatric lung disease
    • Respiratory Structure and Function
    • Pulmonary Circulation
    • Interstitial Lung Disease
    • Other
  • An abstract can have a maximum of two images, JPG, PNG and GIF format ONLY, including figures, tables and images.
  • The recommended image sizes for optimal resolution is
    • A table: up to 5 columns x 8 rows
    • A graphic: 192 pixels wide, 288 pixels high (print size 508 mm (2 inches) wide by 762 mm (3 inches) high and 300 DPI)
  • Authors may request their preferred presentation method to be oral or poster or either. Please be reminded that the Scientific Committee will take the request into consideration but will ultimately decide which method will be allocated to the abstract.
  • ONLY Presenting Authors can apply for an award for the Congress.
  • Please make sure all contents are correct before you Submit your abstract.
  • An abstract submitted can be edited at any time until the abstract submission deadline date. Please click Edit to change a submitted abstract.
  • The Scientific Committee reserves the right to accept or reject an abstract
  • ONLY the Presenting Author will receive abstract correspondence and the presentation confirmation, which will be sent by email.
  • Presenting Authors will be notified of the status of their abstract, session formats, and scheduling of presentations in September 2019.
  • Abstracts accepted and presented during the Congress will be published in a supplement of Respirology, known as the Abstract Book. At least one author of an abstract must register for the Congress before the abstract can be published in the Abstract Book or Congress Guide.

APSR & ISRD Joint Session at the ATS 2019, Dallas

The APSR and the ISRD (International Symposium on Respiratory Diseases) invite you to the 5th Joint APSR-ISRD Session at the prestigious American Thoracic Society (ATS) International Conference, 11:00–16:15, Saturday 18 May 2019 in Dallas Ballroom D (Level 3), Omni Dallas Downtown.

The session includes excellent presentations of top-ranked scientific Oral and Poster abstracts submitted to the ATS Conference by young investigators in the Asia-Pacific region.

Faculty includes:

  • Prof. Chunxue Bai (ISRD President)
  • Prof. Kwun Fong (APSR President)
  • Prof. Yoichi Nakanishi (APSR Secretary General)
  • Prof. Lynn M. Schnapp (ATS Secretary-Treasurer)
  • plus Young Investigator speakers from China and the APSR

Please make a note of the day and we really look forward to seeing you there.

Sincerely yours,
Kwun Fong
President, APSR

Programme

11:00

12:00
Poster Viewing and networking
Facilitators: Dr Chunxue Bai, Dr Erlina Burhan, Dr Kwun Fong, Dr Yoshinori Hasegawa, Dr Young Whan Kim, Dr David Lam, Dr Michiaki Mishima, Dr Yoichi Nakanishi, Dr Yeon-Mok Oh, Dr Chin Kook Rhee, Dr Yuanlin Song, Dr Bruce Thompson, Dr Rex Yung
ISRD   APSR
Dr Xiaohu Wang
West China Hospital, Sichuan University, China
Dr Si Chen
Changhai Hospital, China
Dr Feng Li
Shanghai Chest Hospital, Shanghai Jiao Tong University, China
Dr Yuanling Liu
Guangdong Provincial People's Hospital, China
Dr Lili Guan
Guangzhou Institute of Respiratory Health, the first affiliated hospital of Guangzhou Medical University, China
Dr Yiqing Li
Zhejiang University, China
Dr Jinyuan Zhu
General Hospital of Ningxia Medical University, China
Dr Di Wu
Fuzhou Pulmonary Hospital of Fujian Province, China
Dr Jin Zhang
Cardiovascular Research Center, Xi'an Jiaotong University Health Science Center, China
Dr Xiaojing Liu
The Affiliated Hospital of Qingdao University, China
 
Dr Hisayo Matsuyama
Toho University Omori Medical Center, Japan
Dr Sheng-Wei Pan
Taipei Veterans General Hospital, Taiwan
Dr Weiling Lim
Tan Tock Seng Hospital, Singapore
Dr Youlim Kim
Hallym University Chuncheon Sacred Heart Hospital, Republic of Korea
Dr Toshihiro Sakakibara
Nagoya University Graduate School of Medicine, Japan
Dr Yasushi Murakami
Nagoya University Graduate School of Medicine, Japan
Dr Yet Khor
Austin Health / Alfred Health / University of Melbourne, Australia
Dr Miranda Ween
Royal Adelaide Hospital, Australia
Dr Byung Woo Jhun
Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea
12:00

12:10
Opening and welcome
Dr Chunxue Bai, Dr Kwun Fong
12:10

12:20
Taking a new challenge in JRS
Speaker: Dr Yoshinori Hasegawa
12:20

12:45
ISRD Mini orals chaired by Dr Chunxue Bai
Three-minute talks, followed by one question only.

Dr Xiao-feng Xiong
West China Hospital, Sichuan University, China

Dr Kai Yang
Guangzhou Institute of Respiratory Health, Guangzhou Medical University, China

Dr Yixin Zhang
FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy Medical Sciences & Peking Union Medical College, China

Dr Fen Dong
China-Japan Friendship Hospital, China

Dr Chen Zhu
The Second Affiliated Hospital of Zhejiang University, School of medicine, China

12:45

13:15
Award presentation
Dr Lynn M Schnapp, ATS Secretary-Treasurer, will present the Best Abstract Award to Dr Yohei Korogi of Kyoto University, Japan

Dr Schnapp will then deliver her own talk
followed by Dr Korogi's talk.

13:15

14:00
APSR Mini orals chaired by Dr Kwun Fong
Three-minute talks, followed by one question only.

Dr Clarice Tang
Western Sydney University, Australia

Dr Heeyoung Yoon
Asan Medical Center, Korea

Dr Dorothy Cheong
National University of Singapore, Singapore

Dr Crestita Gorme
Philippine Heart Center, Philippine

Dr Edward Harris
Sir Charles Gairdner Hospital, Australia

14:00

14:10
Tea break
14:10

14:20
Health effects of air Pollution
Speaker: Dr Chau Ngo Quy
14:20

15:20
ISRD Mini orals chaired by Dr Chunxue Bai
Three-minute talks, followed by one question only.

Dr Hao Sun
Jiangsu Province Hospital, China

Dr Hangming Dong
Nanfang Hospital, southern medical university, China

Dr I-Chen Chen
Kaohsiung Medical University Hospital UT Southwestern medical center

Dr Tzu-Han
National Taiwan University College of Medicine, Taiwan

Dr Rui Chen
The University of Hong Kong, Hong Kong

APSR Mini orals chaired by Dr Kwun Fong
Three-minute talks, followed by one question only.

Dr Razia Zakarya
Woolcock Institute of Medical Research, Australia

Dr Jung-Ki Yoon
Seoul National University College of Medicine, Republic of Korea

Dr Masayuki Nakajima
Tsukuba, Japan

Dr Hiroki Tashiro
Saga University, Japan

Dr Edward Harris
Sir Charles Gairdner Hospital, Australia

15:20

15:30
New Panel of Imprinting Genes for Diagnosis and Prognosis of Lung Cancer
Speaker: Dr Chunxue Bai
15:30

15:50
Awards and Closing
15:50

16:15
Group photos

APSR Awardees to attend the ATS International Conference

We are delighted to announce two awardees to attend the ATS 2019, Dallas, to whom we offer sincerest congratulations.

Session videos from 2018 Congress

For a limited period only, we are able to share videos of some of the most popular sessions at the APSR Congress in Taipei, 30 November – 2 December 2018.

The videos are streamed, which means you can see them directly – you do not need to download them.

Plenary Lecture 1Cell and molecular biology – Presidential lecture
Symposium 1COPD 1
Symposium 2Clinical respiratory medicine – Presidents' symposium 1
Symposium 3Respiratory structure and function – Emerging technology for pulmonary structure and function
Symposium 5Interstitial lung disease 1 – Pathology of interstitial lung diseases
Symposium 6Respiratory neurobiology and sleep 1 – The impact of home ventilator over the world
Symposium 7E-cigarette and health
Symposium 9Interstitial lung disease 2 – Clinical management of interstitial lung diseases
Symposium 10Tuberculosis 1 – Addressing MDR-TB in the era of end TB strategy
Symposium 11Environmental & occupational health and epidemiology – Particulate air pollution and cardiopulmonary health
Symposium 13Lung cancer 1 – Treatment for oligometastases
Symposium 14Respiratory infections (non-tuberculous) 1 - Invasive pulmonary fungal infection
Symposium 15Critical care medicine 1 – Update in critical care
Plenary Lecture 2Asthma – Memorial lecture 1: Ann Janet Woolcock Research Award
Symposium 17COPD 2
Symposium 18Clinical respiratory medicine – Presidents' symposium 2
Symposium 19Critical care medicine 2 - Management of acute respiratory failure
Symposium 21Lung cancer 2 – Immunotherapy for lung cancer
Symposium 22Respiratory Infections (non-tuberculous) 2 - Pulmonary diseases caused by non-tuberculous mycobacteria (NTM)
Symposium 23Bronchosopy and interventional techniques – Bronchoscopic treatment of benign lung disease
Symposium 24Lung cancer 3 – Update on targeted therapy
Symposium 25Clinical respiratory medicine 1 – Current state of treatment for pleural disease
Symposium 26Paediatric lung disease 1 – Is bronchopulmonary dysplasia preventable?
Symposium 27Clinical respiratory medicine 2 – Update of lung transplantation
Symposium 28Respiratory neurobiology and sleep 2 – The phenotype of obstructive sleep apnea syndrome
Symposium 29Paediatric lung disease 2 – Pediatric asthma
Plenary Lecture 3Respiratory neurobiology and sleep - Memorial lecture 2: Michiyoshi Harasawa Research Award
Symposium 30Asthma 1 – Phenotypes of severe asthma and evolving treatment
Symposium 31Tuberculosis 2 – Management of latent TB infection (LTBI): An update
Symposium 32Clinical respiratory medicine 3 – Recent advance in thoracic imaging biomarker and functional imaging of the chest
Symposium 33Asthma 2 – Novel pathogenesis of severe asthma
Symposium 34Cell and molecular biology – Molecule- and Cell-based Therapeutics in Advanced Lung Diseases
Symposium 35Clinical allergy and immunology – Allergic pathogenesis of non-allergic airway diseases
PR VideoHanoi Promotion Video

As an APSR member you can see these videos at no charge. Further description of each video and the current access password is shown at apsresp.org/congress/apsr2018/streaming.php.

Travel Award opportunities

The January 2019 issue of the APSR Newsletter includes glowing reports from last year's award winners.

Enjoy similar rewards yourself by taking advantage of the following opportunities:

*"LMIC" is defined as a "lower-middle income country", a list of which can be seen at data.worldbank.org/income-level/low-and-middle-income.

Our Members, Our Future

Continuing this series we are delighted to share a tribute to Prof. Teresita De Guia, prepared by the PCCP.

This series complements our APSR Members' Honour Roll, on which as a member, you are welcome to add your appreciation of your mentor(s) at any time.


Prof. De Guia

A tribute to Prof. Teresita De Guia

Dr Teresita S De Guia is an extraordinary woman who possesses a strong determination, commitment and avid devotion to her craft. She has a remarkable career as a physician, leader and teacher of pulmonary medicine.

A pioneer of pulmonary and critical care medicine in the Philippines, Dr De Guia is looked up to by colleagues as a leader committed to excellence. She established the first respiratory care unit in the country in 1973 at the Veterans Memorial Medical Center. She also started the first structured fellowship training in adult pulmonary and critical care medicine in the Philippines in 1976 at the Philippine Heart Center. This became the model of subsequent training programmes in pulmonary medicine in various medical centres accredited by the Philippine College of Chest Physicians (PCCP). Dr De Guia also started the PCCP convention and became its organizing and scientific chairperson. Thereafter, the annual convention was gradually built up and is now a major activity of the College.

As she continued to make an indelible mark as chair of the Division of Pulmonary and Critical Care Medicine of the Philippine Heart Center, Dr De Guia initiated the first pediatric pulmonary training program in the Philippines in 1981, the first pulmonary rehabilitation unit in the country in 1990 and a Sleep Medicine training programme. She also spearheaded the establishment of the Philippine Foundation for Lung Health Research and Development in 1993. Then as now, she participates actively in the scientific and outreach programmes of the foundation.

Her retirement in 2005 as chairman of the pulmonary division did not wind down her passion for teaching and research. As a tireless teacher, she finds time for pulmonary fellows-in-training for an intellectual journey through her clinical teachings. She is endowed with a unique genre of mentorship that motivates trainees to strive for excellence. Despite her age, Dr De Guia still conducts research. Through the years, she has authored and co-authored several scientific papers which were presented in national and international conventions. Many of these papers were published in both local and international journals. She also became an international editor for the CHEST journal until 1993 and the Respirology journal since 1995.

The exceptional leadership of Dr De Guia has not been limited to the major medical societies in the Philippines. She has been appointed by the Executive Committee as a National GOLD Assembly representative by the Global Initiative for Chronic Obstructive Lung Disease organizing committee. She was also the congress president of the 15th Congress of the Asian Pacific Society of Respirology (APSR) in 2010 and Treasurer of the APSR in 2015-2017.

Her relentless pursue for improvement in the field of pulmonary medicine, coupled with her passion in all her undertakings, makes Dr De Guia truly an icon and deserves the recognition as "mother of pulmonary medicine" in the Philippines.

Prepared by the Philippine College of Chest Physicians (PCCP)

The PCCP's history spans 40 years of achievements and a series of changes that molded the society into what it is today; dynamic with a solid foundation anchored on a people-empowered MISSION and VISION. The society is an APSR en bloc membership society.

Respiratory Updates

The April issue (Vol 11.4) features ARDS and Critical Care:

  • Acute Respiratory Distress Syndrome
  • Acute Respiratory Distress Syndrome, Second Edition
  • Tissue Perfusion and Prognosis in the Critically Ill-Is Renin the New Lactate
  • The Surviving Sepsis Campaign Bundle: 2018 update
  • Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial
  • Fever control in critically-ill adults: An individual patient data meta-analysis of randomized controlled trials
  • Is your smartphone the future of physiologic monitoring?
  • The rise of ward monitoring: opportunities and challenges for critical care specialists
  • What's new on emerging resistant Candida species
  • Does this critically-ill patient with delirium require any drug treatment?
  • Adaptive designs in critically-ill patients: principles, advantages and pitfalls
  • Acute respiratory distress syndrome (ARDS) phenotyping

Inside Respirology

Vol. 24 Issue 5

EDITORIALS
402Severe asthma treated by bronchial thermoplasty: A success not due to the small airways?
Pascal Chanez MD PhD, Laurie Pahus PharmD PhD, Jeremy Charriot MD, Arnaud Bourdin MD PhD
10.1111/resp.13481
404Molecular breath analysis for IPF: Can we make a few breaths count?
Toyoshi Yanagihara MD PhD, Martin Kolb MD PhD
10.1111/resp.13503
406ACCESS ALL AREAS: Electromagnetic navigation and the pulmonologist
Daniel P Steinfort MBBS BMedSci FRACP PhD
10.1111/resp.13508
408Bronchiolitis obliterans syndrome 'endotypes' in haematopoietic stem cell transplantation
Daniel C Chambers MBBS MRCP FRACP MD
10.1111/resp.13498
COMMENTARY
410Severe acute respiratory syndrome and other emerging severe respiratory viral infections
David S Hui MD FRACP, Malik Peiris MBBS DPhil FRCPath
10.1111/resp.13501
INVITED REVIEW SERIES
Paediatric and Adult Bronchiectasis
413Paediatric and adult bronchiectasis: Diagnosis, disease burden and prognosis
Jennifer K Quint, Maeve P Smith
10.1111/resp.13495
INVITED REVIEW
423Why are people with asthma susceptible to pneumonia? A review of factors related to upper airway bacteria
Seher R Zaidi, John D Blakey
10.1111/resp.13528
ORIGINAL ARTICLES
Asthma and Allergy
431
Measuring the effects of bronchial thermoplasty using oscillometry
David Langton, Alvin Ing, Joy Sha, Kim Bennetts, Nicole Hersch, McKinny Kwok, Virginia Plummer, Francis Thien, Claude Farah
10.1111/resp.13439

Oscillometry was used to examine the effects of bronchial thermoplasty on the small airways of 43 patients with severe asthma. No significant effects were demonstrated.

Interstitial Lung Disease
437
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis
Martin Thomas Gaugg, Anna Engler, Lukas Bregy, Yvonne Nussbaumer-Ochsner, Lara Eiffert, Tobias Bruderer, Renato Zenobi, Pablo Sinues, Malcolm Kohler
10.1111/resp.13465

Collagen-related amino acids are significantly increased in exhaled breath of idiopathic pulmonary fibrosis (IPF) patients compared with healthy controls. The detection of these amino acids using real-time breath analysis results in a good discrimination between the groups, indicating the possibility for a rapid, non-invasive screening for IPF.

445Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure – function study
Joseph Jacob, Michael Pienn, Christian Payer, Martin Urschler, Maria Kokosi, Anand Devaraj, Athol U Wells, Horst Olschewski
10.1111/resp.13485

In Idiopathic pulmonary fibrosis (IPF), vessel volume and vessel density link powerfully with forced vital capacity (FVC), total lung capacity (TLC) and composite physiologic index (CPI) but weakly with measures of vasculopathy (diffusion capacity for carbon monoxide (DLCO) and transfer factor for carbon monoxide (KCO)). Vessel volume and heterogeneity are independently linked with DLCO, TLC and CPI. The results reinforce the need for more detailed study of the vasculature in IPF.

Interventional Pulmonology
453Safety and diagnostic performance of pulmonologists performing electromagnetic guided percutaneous lung biopsy (SPiNperc)
Christopher Mallow, Hans Lee, Catherine Oberg, Jeffrey Thiboutot, Jason Akulian, Allen C Burks, Branden Luna, Sadia Benzaquen, Hitesh Batra, Jose Cardenas-Garcia, Jennifer Toth, Jay Heidecker, Adam Belanger, Jason McClune, Umar Osman, Venkatesh Lakshminarayanan, Nicholas Pastis, Gerard Silvestri, Alexander Chen, Lonny Yarmus
10.1111/resp.13471

Lung cancer screening has led to the discovery of over 1 million pulmonary nodules each year. New technology allows pulmonologists to perform percutaneous lung biopsies using electromagnetic (EM) guided technology. In this retrospective analysis, we demonstrate that EM percutaneous needle biopsy is safe, feasible and provides an acceptable diagnostic yield. See related Editorial

Rare Lung Disease
459Rapid versus gradual lung function decline in bronchiolitis obliterans syndrome after haematopoietic stem cell transplantation is associated with survival outcome
Wang-Chun Kwok, Bin-Miao Liang, Macy M S Lui, Terence C C Tam, Joycelyn P Y Sim, Eric W C Tse, Anskar Y H Leung, Yok L Kwong, Albert K W Lie, Mary S M Ip, David C L Lam
10.1111/resp.13472

Patients with post-haematopoietic stem cell transplantation (HSCT) bronchiolitis obliterans syndrome (BOS) who manifested initial rapid lung function decline within 3 months of BOS diagnosis had significantly poorer lung function and worse overall survival compared to those with initial gradual decline in lung function after BOS diagnosis. See related Editorial

Tuberculosis
467Bidirectional association between tuberculosis and sarcoidosis
Sheng-Huei Wang, Chi-Hsiang Chung, Tsai-Wang Huang, Wen-Chiuan Tsai, Chung-Kan Peng, Kun-Lun Huang, Wann-Cherng Perng, Chih-Feng Chian, Wu-Chien Chien, Chih-Hao Shen
10.1111/resp.13482

This bidirectional cohort study strengthens the evidence that tuberculosis (TB) is a risk factor for sarcoidosis. Patients with sarcoidosis showed a higher risk of developing TB within the first year after diagnosis of sarcoidosis.

CONTEMPORARY CONCISE REVIEW
475Contemporary Concise Review 2018: Lung cancer and pleural disease
Francesca M Conway, Justin L Garner, Christopher M Orton, Karthi Srikanthan, Samuel V Kemp, Pallav L Shah
10.1111/resp.13499
REVIEW
484Air pollution in the Asia-Pacific Region: A Joint Asian Pacific Society of Respirology/American Thoracic Society perspective (Republication)
Crystal M North, Mary B Rice, Thomas Ferkol, David Gozal, Christopher Hui, Soon-Hee Jung, Kozo Kuribayashi, Meredith C McCormack, Michiaki Mishima, Yasuo Morimoto, Yuanlin Song, Kevin C Wilson, Woo Jin Kim, Kwun M Fong
10.1111/resp.13531
LETTER FROM ASIA-PACIFIC AND BEYOND
492Letter from France: How structures condition outputs
Nicolas Roche MD PhD
10.1111/resp.13535
CORRESPONDENCE
494Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure
Peter H S Sporn MD, S Marina Casalino-Matsuda PhD, Khalilah L Gates MD
10.1111/resp.13522

See Reply

494Mechanism of benefit of non-invasive ventilation in COPD with hypercapnic respiratory failure – Reply
Marieke L Duiverman MD PhD
10.1111/resp.13547

See Letter

ERRATUM
496Erratum
10.1111/resp.13523

Inside Respirology Case Reports

The following cases have been selected for inclusion in the new July 2019 Respirology Case Reports, Volume 07 Issue 5

Case Reports

Negative pressure wound therapy with instillation without open-window thoracostomy for empyema
Kayo Okamoto, Kumiko Matsumoto, Norichika Iga, Seiji Komatsu
DOI: 10.1002/rcr2.417

Here we present the cases of two patients with refractory empyema after intrathoracic irrigation and drainage, who underwent a new treatment with negative pressure wound therapy with instillation and dwell time (NPWTi-d) but without open-window thoracostomy (OWT) using the fistula of the thoracic drain. We called this treatment non-OWT NPWTi-d. Both the patients recovered. Non-OWT NPWTi-d may be a new option to treat empyema.

Massive haemoptysis from right middle lobe bronchus managed by customized silicon stents
Weihua Xu, Hongwei Wang, Haidong He, Huiping Hu, Haihua Lu, Guozheng Li
DOI: 10.1002/rcr2.418

Here we report a patient with bronchiectasis who developed massive haemoptysis. Two straight customized silicone stents were used to control haemoptysis.

A 27-year-old female presented with diffuse alveolar haemorrhage due to breast angiosarcoma with lung metastasis
Po-Hsin Lee, Yun-An Chen, Pin-Kuei Fu
DOI: 10.1002/rcr2.419

We report a case of a 27-year-old female with the diagnosis of primary breast angiosarcoma developing DAH. This raised our concern that angiosarcoma with lung metastasis may present with diffuse alveolar haemorrhage (DAH) and should be considered as an important fatal differential diagnosis of DAH.

Tension hydrothorax secondary to small cell lung cancer
Eleah Danielle Porter, David John Finley, Joseph David Phillips
DOI: 10.1002/rcr2.420

Tension hydrothorax is uncommon and a malignant aetiology is rare. Here we present a case of malignant tension hydrothorax secondary to small cell lung cancer and highlight management strategies to prevent the life-threatening complication of re-expansion pulmonary oedema.

Dyspnoea and restrictive lung disease due to mediastinal and pleural lipomatosis in morbid obesity
Jen Yuh Lim, Kim A McAnulty, Catherina L Chang
DOI: 10.1002/rcr2.421

Exertional dyspnoea in obesity is common and may be due to a number of factors. We report a case of large volume mediastinal and pleural lipomatosis causing significant dyspnoea in an obese individual. This is a rare complication of obesity and should be considered in obese patients when other causes of dyspnoea have been excluded.

A case of pulmonary lymphoproliferative disorder presenting rapidly progressive respiratory failure
Kohei Fujita, Kenjiro Ishigami, Hiroyuki Tanaka, Koki Moriyoshi, Tadashi Mio
DOI: 10.1002/rcr2.422

A 72-year-old woman presented with acute onset of shortness of breath and fatigue over several days, and was found to be in acute respiratory failure. Computed tomography of the chest revealed massive ground-glass opacity and partial crazy-paving appearance with multiple nodules across all the lobes of the lung and a large mass in the right lower lobe. She was diagnosed with B-cell lymphoma and the abnormal lung shadow was considered to be a result of a pulmonary lymphoproliferative disorder (PLD). PLD is known to present with various radiographic patterns. However, the progression of PLD is usually slow, and acute respiratory failure is very rare. Physicians should be aware that acute respiratory failure can be caused by PLD.

Mediastinal emphysema after long-distance flight with ketoacidosis and underlying diabetes mellitus type 1
Gracia Lana Ardila Pardo, Wolfgang Michael Kübler Martin, Witzenrath, Jörg-Wilhelm Oestmann
DOI: 10.1002/rcr2.423

Spontaneous pneumomediastinum (SPM) is a rare differential diagnosis of acute chest pain and dyspnoea. Clinical symptoms may be subtle. A number of risk factors increase the chance of SPM. SPM normally regresses spontaneously within a few days. We present a 21-year-old female with diabetes mellitus type 1 diagnosed with SPM which improved after four days with conservative treatment.

Phlegmasia cerulea dolens: a rare cause of shock
Christopher Bob Lewis, Matthew Kevin Hensley, Julie Elizabeth Barrett, Steven Burke Van Norman, Alexander Stuart Taylor, Jeffrey Craig Horowitz
DOI: 10.1002/rcr2.424

Phelgmasia cerulea dolens (PCD) is a rare cause of shock that can complicate deep venous thrombosis and carries a high risk of mortality. We present a case of extensive bilateral lower extremity deep vein thrombosis associated with an inferior vena cava filter, which rapidly progressed to PCD and refractory shock.

A rare epidermal growth factor receptor H773L/V774M compound mutation in advanced non-small-cell lung cancer with poor response to epidermal growth factor receptor tyrosine kinase inhibitor
Lun-Che Chen, Jin-Yuan Shih, Chong-Jen Yu, Ching-Yao Yang
DOI: 10.1002/rcr2.425

Here, we report a case of advanced non-small-cell lung cancer with a rare epidermal growth factor receptor (EGFR) exon 20 H773L/V774M compound mutation, which demonstrated poor clinical response to afatinib, a second-generation EGFR-TKI with pan-human EGFR blocking activity. The anti-cancer treatment was shifted to platinum-based chemotherapy, which resulted in a partial response.

Severe mediastinitis over a month after endobronchial ultrasound-guided transbronchial needle aspiration
Kana Kurokawa, Tetsuhiko Asao, Ryo Ko, Tetsutaro Nagaoka, Kenji Suzuki, Kazuhisa Takahashi
DOI: 10.1002/rcr2.426

Mediastinitis is a concerning acute or subacute complication of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The median time of mediastinitis onset is approximately 12 days after EBUS-TBNA. Here we present the first report, to the best of our knowledge, of mediastinitis occurring over a month after EBUS-TBNA in two patients.

Transoesophageal ultrasound-guided bronchoscopic aspiration of a superior mediastinal tumour using the BF-UC290F instrument
Daisuke Minami, Yuki Takigawa, Hiroe Kayatani, Ken Sato, Keiichi Fujiwara, Takuo Shibayama
DOI: 10.1002/rcr2.427

The BF-UC290F is a third-generation, reliable, Olympus, endobronchial, ultrasound-guided, needle aspiration endoscope. We report a case with a superior mediastinal mass diagnosed via endoscopic, ultrasound-guided, bronchoscopic fine-needle aspiration using the BF-UC290F.

Mycobacterium shimoidei, a rare non-tuberculous mycobacteria pathogen identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Hiroaki Nagano
DOI: 10.1002/rcr2.428

The purpose of this study is to communicate the potential utility of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for identification of Mycobacterium shimoidei that is not identifiable by DNA-DNA hybridization. This is essential for choice of the appropriate antimicrobial treatment. Notably, this is also the first identification of M. shimoidei in Okinawa, the southernmost and only prefecture categorized as subtropical in Japan.

An unusual endobronchial lesion: expanding the differential diagnosis
Rachel Leonard, Charles Schultz, Sarah Hadique
DOI: 10.1002/rcr2.429

Here, we report a case of a 73-year-old male who presented to the hospital after a motor vehicle collision, with incidentally found pulmonary nodule and kidney mass. He was eventually diagnosed with high-grade synovial sarcoma, one of only seven cases to date of primary endobronchial synovial sarcoma that have been reported. A review of the cases and literature is carried out.

Regional society news

The spotlight this month is on

INDONESIA

Each month we share details of activities of a particular country, region or society.

If you would like the spotlight to be on your country, region or society next month, contact the Bulletin Coordinator or APSR Secretariat.

Indonesian Society of Respirology (ISR)
Activity report for 2018

(Click any image to enlarge)


















IRS Secretariat

Rumah PDPI (ISR Building)
Jalan Cipinang Bunder No. 19 Cipinang Pulogadung
Jakarta
13240
Indonesia
tel: +6221-4705685
fax: +6221-4705685
sekretariat@klikpdpi.com
www.klikpdpi.com

Other notable society events and news:

Hong Kong

Hong Kong Thoracic Society

Regarding recent discussions over the issue of heat-not-burn products and e-cigarettes, the Hong Kong Thoracic Society has reiterated its anti-smoking stance against all heat-not-burn products, herbal cigarettes and other similar products.

The Society firmly believes that:

  1. Any partial or non-comprehensive regulations the HKSAR Government might implement on these tobacco products which allow their future sale and use in Hong Kong are totally inadequate.
  2. A TOTAL BAN of all e-cigarettes, heat-not-burn products and other new tobacco products by legislation is the only solution to safe-guard the public especially young people against their harmful effects on health.


Dr Lam

Dr David C L Lam
President, Hong Kong Thoracic Society

Dr Jenny C L Ngai
Hon. Secretary, Hong Kong Thoracic Society

Click here for HKTS Statement.

Republic of Korea

Korean Association of Tuberculosis and Respiratory Disease

(Click image to enlarge)

The 3rd symposium of the Environmental Lung Disease research group of the KATRD was held on 23 March 2019 in Seoul, Republic of Korea.

Air pollution and humidifier-disinfectant associated respiratory diseases were discussed with researchers in these fields.

Professor Dean Schraufnagel, the director of FIRS, gave a special talk on "International acts on clean air and role of respiratory societies". The talk traced the recent activities of FIRS, its interaction with WHO and the UN, and how it strives to improve global respiratory health.

Extra-regional societies

Panama

The 12th Congress of the Asociación Latinoamericana del Tórax (ALAT) will take place at the ATLAPA Convention Center in Panama City 3–6 July 2019.

By the kind invitation of Congress Scientific Committee, Dr Kwun Fong (APSR President) and Dr David C L Lam (Immediate Past Chair of the APSR Education Committee) will be the APSR's representative speakers at the Congress.

The symposium APSR–ALAT–WHO essential medicine for respiratory illnesses: unique window of opportunity to address global equity, will be held on 08:00 – 10:00 on 6 July in La Huaca Room of the conference centre:

  • "Access of essential medicines in smoking cessation"
    Dr David C L Lam
  • "Access of essential drugs in COPD: LAMA"
    Dr Rogelio Perez Padilla
  • "Access of essential medicines in lung cancer"
    Dr Kwun Fong
  • "Access of essential medicines in Asthma: LABA / ICS"
    Dr Federico Daniel Colodenco
  • Q&A

The APSR is looking forward to collaborating further with the ALAT in the future.

Health news

News from Europe



For many people in the Asia-Pacific, "News from Europe" evokes thoughts of the recent fire at Notre-Dame Cathédral or the burning issue of Brexit.

Repairing the structure of the Cathedral could be as monumental as restructuring Europe after Brexit.

In both cases, how that restructuring is done will naturally determine the result.

And this leads us to the appropriate title of a European article on lung health, published in the latest copy of Respirology: How structures condition outputs.

In addition to the article's focus on the structures and policies of respiratory societies, a wise footnote reminds us that the involvement of "young respiratory physicians ... is of utmost importance as they represent the future".

To this end, the APSR is paying increasing importance in encouraging early-career members to attend the annual congress and workshops, through the various annual awards and scholarships.

Read Letter from France: How structures condition outputs at 10.1111/resp.13535

Two World Days of special interest this month:

Education

Emerging respiratory infections threatening public health in the Asia-Pacific region: A position paper of the Asian Pacific Society of Respirology

This position statement has been prepared by members of the Respiratory Infections Assembly and is now published in the latest issue of Respirology:
"Emerging respiratory infections threatening public health in the Asia-Pacific region: A position paper of the Asian Pacific Society of Respirology"; Sunghoon Park, Ji Young Park, Yuanlin Song, Soon Hin How, Ki-Suck Jung. First published 15 April 2019 10.1111/resp.13558

Webinars from the Thoracic Society of Australia and New Zealand (TSANZ)

The TSANZ are now streaming the following webinars for public viewing:

  • The Human Respiratory Virome
  • NIV Therapy – viewed via a community lens
  • Accelerated Silicosis, kitchen benchtops and the emerging epidemic
  • Research Techniques To Study Respiratory Diseases
  • What's in a cough? Implications for the care of people with flu and MROs
  • Primary Ciliary Dyskinesia: Common symptoms from an uncommon condition
  • The Impact of Climate Change on Respiratory Health
  • What we have learned about children who present to hospital with acute wheeze
  • How respiratory specialists can best assist smoking patients to quit

To access any of the above, click www.thoracic.org.au/events/category/past-tsanz-webinars-on-demand-recordings. Note that for non-TSANZ members, some of the above webinars require payment of a A$10 (plus A$1 GST) pay-as-you-view fee to the TSANZ.

New educational articles

The following article has recently been selected from Respirology for its specific educational value. Previous articles on further topics can be seen at apsresp.org/education/articles/index.html


(Click image to enlarge)

Of special interest to those working in:
* Clinical Respiratory Medicine
* Tuberculosis
* Interstitial Lung Disease

Bidirectional association between tuberculosis and sarcoidosis Sheng-Huei Wang, Chi-Hsiang Chung, Tsai-Wang Huang, Wen-Chiuan Tsai, Chung-Kan Peng, Kun-Lun Huang, Wann-Cherng Perng, Chih-Feng Chian, Wu-Chien Chien and Chih-Hao Shen
onlinelibrary.wiley.com/doi/10.1111/resp.13482 (May 2019)

Comment by Dr Mark Lavercombe:
This cohort study demonstrates the difficulty of differentiating sarcoidosis and tuberculosis. The diagnosis of tuberculosis within one year of sarcoidosis diagnosis occurred at a significant rate, suggesting the possibility of misdiagnosis. Further, subsequent diagnosis of sarcoidosis in patients treated for tuberculosis is significant after the first year of follow-up.

APSR Membership

Donations received

have kindly sent their donations towards the Society's goals, as outlined at apsresp.org/members/donors.php.

The APSR is profoundly grateful for their generosity.

New Fellows of the APSR

Congratulations to the following members who have recently become APSR Fellows.

  • Dr Fitri Indahyanti FAPSR (Indonesia)
  • Dr Suryanti Dwi Pratiwi FAPSR (Indonesia)
  • Dr Ngakan Putu Parsama Putra FAPSR (Indonesia)
  • Dr Hendri Wiyono FAPSR (Indonesia)
  • Dr Dwi Yuliati FAPSR (Indonesia)

Assembly news

We are pleased to report the successful publication of a position paper by the Respiratory Infections Assembly.

The paper Emerging respiratory infections threatening public health in the Asia-Pacific region was prepared by Dr Sunghoon Park, Dr Ji Young Park, Dr Yuanlin Song, Dr Soon Hin How and Dr Ki-Suck Jung, and published 15 April 2019 in Respirology: 10.1111/resp.13558

We are looking forward to seeing publication of further papers from this and other Assemblies in due course.

We are also pleased to announce a new Assembly Newsletter has been uploaded to the Respiratory Neurobiology and Sleep Assembly webpage, giving some important news for early-career doctors.

New assembly members

A warm welcome to the following members who have recently joined APSR assemblies. They will undoubtedly enjoy working with and networking with their assembly colleagues.

Assemblies
Devanand Anantham
(Singapore)
Bronchoscopy and Interventional Techniques
Lung Cancer
Clinical Respiratory Medicine
Fitri Indahyanti FAPSR
(Indonesia)
Tuberculosis
COPD
Asthma
Ho James
(Hong Kong )
Lung Cancer
Clinical Respiratory Medicine
Jin Suk Lee
(Republic of Korea)
Cell and Molecular Biology
Respiratory Infections (non-tuberculous)
Environmental & Occupational Health and Epidemiology
Yick Hou Lim
(Singapore)
Clinical Respiratory Medicine
Respiratory Infections (non-tuberculous)
Teruaki Mizobuchi
(Japan)
Lung Cancer
Respiratory Structure and Function
Bronchoscopy and Interventional Techniques
Aamir Nadeem
(India)
Clinical Respiratory Medicine
Tuberculosis
COPD
Sze Hang Calvin Ng FAPSR
(Hong Kong )
Bronchoscopy and Interventional Techniques
Lung Cancer
Pee Hwee Pang
(Singapore)
Asthma
Lung Cancer
Critical Care Medicine
Suryanti Dwi Pratiwi FAPSR
(Indonesia)
Lung Cancer
Cell and Molecular Biology
Interstitial Lung Disease
Ngakan Putu Parsama Putra FAPSR
(Indonesia)
Bronchoscopy and Interventional Techniques
Lung Cancer
Critical Care Medicine
Alan Sihoe
(Hong Kong)
Lung Cancer
Bronchoscopy and Interventional Techniques
Respiratory Structure and Function
Santhakumar Subramanian
(India)
Bronchoscopy and Interventional Techniques
Clinical Respiratory Medicine
Interstitial Lung Disease
Terence Tam
(Hong Kong )
Bronchoscopy and Interventional Techniques
Lung Cancer
Clinical Respiratory Medicine
Kin Wang To
(Hong Kong )
Respiratory Neurobiology and Sleep
Clinical Respiratory Medicine
Interstitial Lung Disease
Wira Winardi
(Indonesia )
Lung Cancer
Clinical Respiratory Medicine
Critical Care Medicine
Hendri Wiyono FAPSR
(Indonesia)
Lung Cancer
Bronchoscopy and Interventional Techniques
Tuberculosis
Tin chiu Wong
(Hong Kong )
COPD
Tuberculosis
Lung Cancer
Yasuhiro Yamaguchi
(Japan)
COPD
Respiratory Neurobiology and Sleep
Respiratory Infections (non-tuberculous)
Dwi Yuliati FAPSR
(Indonesia)
Tuberculosis
COPD
Asthma

Future Pulmonology Events

Here are the main respiratory events in Asia-Pacific region for the next few months. You can see our full listing on the APSR Calendar.

  • World Asthma Day
    7 May 2019, Worldwide
    (Details)
  • Asthma & COPD Outpatient Care Unit (ACOCU) Network Day
    12 May 2019, Ho Chi Minh City, Vietnam
    (Details)
  • 92nd annual meeting of Japan Society for Occupational Health
    22–25 May 2019, Nagoya, Japan
    (Details)
  • World No Tobacco Day
    31 May 2019, Worldwide
    (Details)
  • MTS Annual Congress 2019
    18-21 July 2019, Kuala Lumpur, Malaysia
    (Details)
  • Annual Scientific Congress of Ho Chi Minh City Society of Asthma, Allergy & Clinical Immunology
    21 July 2019, Ho Chi Minh City, Vietnam
    (Details)
  • World Lung Cancer Day
    1 August 2019, Worldwide
    (Details)
  • 16th Annual Meeting: Work Conference of the Indonesian Society of Respirology (ISR)
    11-14 September 2019, Surakarta, Central Java, Indonesia
    (Details)
  • World Lung Day
    25 September 2019, Worldwide
    (Details)
  • WASOG/JSSOG 2019 (Joint Conference of International Conference on Sarcoidosis and Interstitial Lung Diseases 2019, and 39th Annual Meeting of Japan Society of Sarcoidosis and other Granulomatous Disorders)
    9–11 October 2019, Yokohama International Conference Center, Pacifico Yokohama, Japan
    (Details)
  • Autumn Respiratory Seminar 2019 of the Hong Kong Thoracic Society and CHEST Delegation Hong Kong and Macau Limited
    November (to be confirmed), Hong Kong
    (www.hktsmeetings.com (under construction)
  • PULMOCON 2019 (6th International Conference on Lung Health of BLF)
    4–6 November, Dhaka, Bangladesh
    (Details)
  • 128th Conference of the Korean Academy of Tuberculosis and Respiratory Diseases (KATRD)
    7–8 November 2019, Seoul, Republic of Korea
    (Details)
  • 24th Congress of the APSR
    14–17 November 2019, Hanoi, Vietnam
    (Details)
  • Asthma & COPD Outpatient Care Unit (ACOCU) Network Day
    17 November 2019, Ho Chi Minh City, Vietnam
    (Details)
  • World Lung Day
    12 November 2019, Worldwide
    (Details)
  • World COPD Day
    20 November 2019, Worldwide
    (Details)

For more pulmonology events, see apsresp.org/calendar.html
(These events are for information only and APSR endorsement should not be assumed.)

Contact

If you have news or announcements that may be of interest to other APSR members, please send details to Bulletin Coordinator Dr Arata Azuma (a-azuma@nms.ac.jp) or APSR Bulletin (bulletin@apsresp.org).


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