No. 131 (June 2020)
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COVID-19 update
APSR News
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COVID-19 update

New Respirology articles on the coronavirus

  • The role of SARS-CoV-2 antibodies in COVID-19: Healing in most, harm at times
    Martyn A French MBChB, MD, FRCPath, FRCP, FRACP; Yuben Moodley MBChB, FCP, FRACP, MD, PhD DOI: 10.1111/resp.13852
    First published 20 May 2020
  • Serum amyloid A is a predictor for prognosis of COVID-19
    Xiao-Neng Mo, Zhu-Quan Su, Chun-Liang Lei, Di-Fei Chen, Hui Peng, Ru-Chong Chen, Ling Sang, Hong-Kai Wu, Shi-Yue Li
    DOI: 10.1111/resp.13840
    First published 14 May 2020
  • Safe performance of diagnostic bronchoscopy/EBUS during the SARS-CoV-2 pandemic
    Daniel P Steinfort, Felix J F Herth, Louis B Irving, Phan T Nguyen DOI: 10.1111/resp.13843
    First published 13 May 2020
  • Chloroquine and hydroxychloroquine for COVID‐19: A word of caution
    Srinadh Annangi DOI: 10.1111/resp.13845
    First published 11 May 2020
  • Rationale for universal face masks in public against COVID‐19
    Anthony Paulo Sunjaya MD, SM; Christine Jenkins MD, AM, FRACP DOI: 10.1111/resp.13834
    First published 30 April 2020

  •  
    In addition to COVID-19 articles, this special Respirology collection includes information and lessons learnt from previous pandemics.

Recent Respirology Case Reports on the coronavirus

  • A 55-year-old COVID-19-positive man managed with self-regulation of high-flow oxygen by high-velocity nasal insufflation therapy
    Ari J Ciment, Lawrence M Ciment
    DOI: 10.1002/rcr2.591
    First published 21 May 2020
  • As with the special Respirology collection mentioned above, there is a collection Respirology Case Reports on COVID-19 and older coronaviruses which you can read here

Podcasts

Podcasts of the webinars held on 22 and 29 April can be heard at anchor.fm/apsr. Click here for the 22 April webinar programme, video, slides and Q&A, and here for the 29 April webinar programme, video, slides and Q&A

APSR News

Lung Cancer Assembly news


Dr Emily Stone
Lung Cancer
Assembly Head

As we are all aware, public health and medical communities around the Asia-Pacific region are dealing with the COVID-19 pandemic.

This dominates the clinical working life of many at the moment, whether in dealing with large numbers of patients or in the planning and prevention of an overwhelming medical crisis.

In countries such as Australia and New Zealand, which have so far had relatively low case numbers, the pandemic has had a marked effect on "business as usual" with a slow-down in non-COVID research activity, a reduction in surgical activity, a reduction in emergency department presentations and an increase in telehealth consultations.

While the impact of these changes on lung cancer outcomes is not yet clear, there are concerns about the effects of social isolation on smoking rates as well as about access to treatments and worries about the immunosuppressive effects of cancer therapy in the midst of a viral pandemic.

Many local and international meetings have been cancelled or postponed although on a happy note, the Australian Lung Cancer Conference was held in Melbourne in February 2020, "just in time" and was an excellent opportunity for the sharing of research and ideas.

This was particularly so for lung cancer screening with presentation of a number of abstracts from the International Lung Screen Trial (ILST), which includes sites from Australia, Canada and Hong Kong.

The Lung Cancer Assembly members are grateful for the support and commitment of colleagues during this difficult time and look forward to meeting again, when we can, to advance clinical care and research in the region.

Congress news

New dates

The following announcement was made on 24 April 2020

To all concerned;



We are writing to inform you that the APSR Executive Committee has regretfully decided to postpone the 25th Congress of the Asian Pacific Society of Respirology originally scheduled in Kyoto, Japan for 15-18 October in 2020 after careful evaluation of the potential risks to our members, delegates and communities caused by the COVID-19 pandemic. We would like to reiterate our gratitude for your kind support and solidarity for the 25th Congress of the APSR.

New dates of the Congress have been scheduled for 18-21 November 2021 at the Kyoto International Convention Center in the same venue as we originally secured. Eventually the 26th Congress of the APSR in Seoul, Republic of Korea will also be postponed to 2022.

We understand that you may have been concentrating on caring for patients and conducting important research during this critical time, and hope our decision to postpone will enable respirologists all over our region to better care for affected people.

The APSR recognizes the vital importance of research and education for this virus and also other lung conditions especially the Chronic Respiratory Diseases (CRDs), and so we are planning a very active schedule of educational Webinars for COVID-19 and other lung conditions with colleagues, sponsors and others until the next Congress. Details will be announced soon, as detail are confirmed.

We are determined with your help, to use modern digital technology to follow our Mission which is to advance and promote of knowledge of the respiratory system in health and disease, by encouraging research, improving clinical practice through teaching, increasing awareness of health problems and promoting the exchange of knowledge among respirologists in the Asia-Pacific region. Indeed, the APSR has just established the new section of e-Health, which we believe will become increasing important.

On behalf of the APSR, we look forward to your understanding of our congress postponements and appreciate your patience during this unprecedented public health crisis. Please take appropriate precautions to stay healthy.

Sincerely yours,

Yoichi Nakanishi, President
Shu Hashimoto, Congress President, 25th Congress of the APSR
Kazuto Matsunaga, Chairperson, Central Congress Committee
Suga Konno, Executive Manager

APSR website

You might have noticed one or two style changes in this Bulletin, also changes appearing on pages of the APSR website.

The project is ongoing and improvement ideas are always welcome by the Secretariat at APSRinfo@theapsr.org

Inside Respirology

Respirology Vol. 25 Issue 5

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EDITORIALS
464Silicosis: An ancient disease in need of a dose of modern medicine
Ryan Hoy MBBS, FRACP, MOccEnvHlth; Daniel C Chambers MBBS, MRCP, FRACP, MD
10.1111/resp.13766
466Time to embrace POCUS as part of the bedside diagnosis of respiratory diseases
José M Porcel MD, FACP, FCCP, FERS
10.1111/resp.13692
468Community-acquired pneumonia due to drug-resistant Enterobacteriaceae: A global perspective
Stephen J Aston MRCP, DTM&H, PhD; Daniel G Wootton MRCP, DTM&H, PhD
10.1111/resp.13720
COMMENTARIES
470Oxygen therapy for pulmonary arterial hypertension: We need to rethink and investigate
Simon Green PhD Deidre Stuart PhD
10.1111/resp.13797
472Efforts to control air pollution in the Asia-Pacific region
Yasuo Morimoto MD, PhD; Hena Khatun MBBS, MD; Kwok Sang Wilson Yee MD; Agus Dwi Susanto MD, PhD; Jun-Pyo Myong MD, PhD; Joven Jeremius Tanchuco MD, MHA; Chau-Chyun Sheu MD; Ngo Quy Chau MD, PhD; Arata Azuma MD, PhD
10.1111/resp.13800
INVITED REVIEW SERIES
New frontiers in sleep-disordered breathing
475A review of approaches for analysing obstructive sleep apnoea-related patterns in pulse oximetry data
Philip I Terrill
10.1111/resp.13635
486Big Data in sleep apnoea: Opportunities and challenges
Jean-Louis Pépin, Sébastien Bailly, Renaud Tamisier
10.1111/resp.13669
INVITED REVIEW
495Health impacts of bushfire smoke exposure in Australia
Clare M Walter, Elena K Schneider-Futschik, Luke D Knibbs, Louis B Irving
10.1111/resp.13798
ORIGINAL ARTICLES
Asthma and Allergy
502Alternaria induces airway epithelial cytokine expression independent of protease-activated receptor
Michael Daines, Lingxiang Zhu, Rhea Pereira, Xu Zhou, Cheryl Bondy, Barry M Pryor, Jin Zhou, Yin Chen
10.1111/resp.13675

Protease-activated receptor 2 (PAR2)-mediated signalling pathway has been implicated in most of the biological activities induced by Alternaria (Alt), an allergen associated with allergic rhinitis and bronchial asthma. Using both in vivo and in vitro models, we have demonstrated that Alt-induced airway inflammation and epithelial cytokine expression were independent of PAR2 signalling.

Environmental and Occupational Lung Disease
511miRNA sequencing reveals miRNA-4508 from peripheral blood lymphocytes as potential diagnostic biomarker for silica-related pulmonary fibrosis: A multistage study
Minjie Chu, Shuangshuang Wu, Wei Wang, Liping Mao, Yuhui Yu, Liying Jiang, Weiyan Yuan, Mingjiong Zhang, Lingli Sang, Qiqing Huang, Tian Tian, Lei Han, Xun Zhuang, Zuo-Feng Zhang, Jianqing Wu
10.1111/resp.13714

RNA sequencing screening and two independent validation studies consistently revealed that the expression of miRNA-4508 in peripheral blood lymphocytes was significantly lower in silica-related pulmonary fibrosis (SPF) cases than in healthy controls. Receiver operating characteristic analysis showed that miRNA-4508 could distinguish SPF cases from healthy controls with high sensitivity and specificity.

518
Artificial stone-associated silicosis in China: A prospective comparison with natural stone-associated silicosis
Na Wu. Changjiang Xue. Shiwen Yu. Qiao Ye
10.1111/resp.13744

High silica content of artificial stone and uncontrolled dry cutting and grinding presents as a high risk of developing accelerated silicosis. Compared to natural stone-associated silicosis, artificial stone-associated silicosis was characterized by short latency, rapid radiological progression, accelerated decline in lung function and high mortality in this study.

Interstitial Lung Disease
525
Acute exacerbations of fibrotic interstitial lung diseases
Atsushi Suzuki, Yasuhiro Kondoh, Kevin K Brown, Takeshi Johkoh, Kensuke Kataoka, Junya Fukuoka, Tomoki Kimura, Toshiaki Matsuda, Toshiki Yokoyama, Jun Fukihara, Masahiko Ando, Tomonori Tanaka, Naozumi Hashimoto, Koji Sakamoto, Yoshinori Hasegawa
10.1111/resp.13682

This study reveals that all forms of fibrotic interstitial lung diseases (FILD) are at risk of acute exacerbations (AE) and have similar outcomes to AE of idiopathic pulmonary fibrosis (AE-IPF). Clinicians are recommended to consider all forms of FILD to be at risk of AE.

Lung Cancer
535Relevance of lung ultrasound in the diagnostic algorithm of respiratory diseases in a real-life setting: A multicentre prospective study
Luca Rinaldi, Stefania Milione, Maria Chiara, Fascione Pia, Clara Pafundi, Concetta Altruda, Mafalda Di Caterino, Lucio Monaco, Alfonso Reginelli, Fabio Perrotta, Giovanni Porta, Mario Venafro, Carlo Acierno, Davide Mastrocinque, Mauro Giordano, Andrea Bianco, Ferdinando Carlo, Sasso Luigi, Elio Adinolfi
10.1111/resp.13659

Lung ultrasound (LUS) provided a useful diagnostic workup of respiratory disease, either by directly identifying pathological findings or by detecting indirect signs of illness, as in lung cancer. Overall, LUS was not inferior to chest radiography and routine use in medical wards or in emergency department settings is beneficial.

Respiratory Infections
543Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia
David Villafuerte, Stefano Aliberti, Nilam J Soni, Paola Faverio, Pedro J Marcos, Richard G Wunderink, Alejandro Rodriguez, Oriol Sibila, Francisco Sanz, Ignacio Martin-Loeches, Francesco Menzella, Luis F Reyes, Mateja Jankovic, Marc Spielmanns, Marcos I Restrepo, GLIMP Investigators
10.1111/resp.13663

Hospitalized adults with community-acquired pneumonia (CAP) have low prevalence of Enterobacteriaceae (EB, 6%) and multidrug-resistant (MDR)-EB (1.2%), respectively. Specific risk factors, such as prior extended-spectrum beta-lactamase infection and being underweight, should raise the clinical suspicion for EB and MDR-EB in patients hospitalized with CAP.

CONTEMPORARY CONCISE REVIEW
552Contemporary Concise Review 2019: Sleep and ventilation
Bernie Y Sunwoo, Christopher N Schmickl, Atul Malhotra
10.1111/resp.13781
LETTER FROM ASIA-PACIFIC AND BEYOND
559Letter from Belgium
Tania Maes PhD
10.1111/resp.13787

Inside Respirology Case Reports

Respirology Case Reports, Volume 08 Issue 5

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Case Series
Interstitial lung disease induced by docetaxel and ramucirumab chemotherapy after nivolumab treatment
Komugi Okeya, Yukio Kawagishi, Mako Yamoto, Mami Shimizu, Toshihide Imizuda, Hiroshi Tsuji
DOI: 10.1002/rcr2.564

We report cases of three patients who developed interstitial lung disease (ILD) during combination therapy with docetaxel and ramucirumab after nivolumab treatment.

Granulomatous lymphocytic interstitial lung disease: limiting immunosuppressive therapy—a single-centre experience
Thomas J Beaton, David Gillis, Karen Morwood, Michael Bint
DOI: 10.1002/rcr2.565

Granulomatous lymphocytic interstitial lung disease (GLILD) can be a progressive ILD-associated common variable immunodeficiency (CVID) that results in increased mortality. There are no treatment guidelines; however, progressive disease often responds to immunosuppression when intravenous immunoglobulin g (IVIg) monotherapy fails. This series adds evidence that immunosuppression can be limited with close observation in clinically stable patients and some patients can consider ceasing immunosuppression when disease has initially responded.

Case Reports
Non-invasive ventilation and airway exchange catheter using a novel adapter in a difficult airway patient with post-extubation respiratory failure
Oscar Ivan Quintero Osorio, Janer V Arenas, Juan A Cuervo, Gustavo A Ospina Tascón
DOI: 10.1002/rcr2.558

We describe the case of a woman with a difficult airway who developed post-extubation respiratory failure. We provided successful non-invasive ventilation support using a novel tube adapter for non-invasive mechanical ventilation, which improved the patient's adaptation to a nasoenteric tube and an oronasal mask. Simultaneously, an airway exchanger catheter placed in the trachea was maintained in situ until emergency reintubation risk was overcome.

Longitudinal lung involvement of systemic lupus erythematosus-related vasculitis and alveolar proteinosis-like reaction
Takahito Suzuki, Noriyuki Enomoto, Yasuoki Horiike, Kazuhiro Asada, Toshihiro Shirai, Takafumi Suda
DOI: 10.1002/rcr2.559

Here, we present a case of systemic lupus erythematosus (SLE)-related lung vasculitis concomitantly with pulmonary alveolar proteinosis (PAP)-like reaction in a 44-year-old woman.

Pembrolizumab-induced secondary sclerosing cholangitis in a non-small cell lung cancer patient
Sachiko Matsumoto, Keisuke Watanabe, Nobuaki Kobayashi, Kuniyasu Irie, Shoji Yamanaka, Takeshi Kaneko
DOI: 10.1002/rcr2.560

Pembrolizumab, a humanized anti-programmed cell death-1 (PD-1) monoclonal antibody, demonstrates efficacy in treating non-small cell lung cancer (NSCLC). However, it can cause immune-related adverse events (irAEs), including inflammatory manifestations. Cholangitis is a rare irAE. Herein, we report on an NSCLC patient who developed pembrolizumab-induced cholangitis and review the relevant literature.

Successful treatment of pyopneumothorax with bronchopleural fistula using endobronchial Watanabe spigots
Chan Sin Chai, Swee Kim Chan, Sze Shyang Kho, Mei Ching Yong, Siew Teck Tie
DOI: 10.1002/rcr2.562

We describe a case of necrotizing pneumonia complicated with bronchopleural fistula (BPF) and pyopneumothorax which was treated successfully with endobronchial Watanabe spigot (EWS). This case highlights the role of EWS in the management of BPF in patients with high surgical risk.

Pulmonary alveolar proteinosis after lung transplantation
Chandima Divithotawela, Simon H Apte, Maxine E Tan, Tharushi A De Silva, Daniel C Chambers
DOI: 10.1002/rcr2.566

Here, we report a case of secondary pulmonary alveolar proteinosis (PAP) after double lung transplantation with highly oxidized protein and pro-inflammatory gene expression in whole lung lavage (WLL) fluid. Our patient was successfully treated with WLL. His repeat bronchoalveolar lavage (BAL) fluid analysis showed reduced lipofuscin and normalized macrophage size and gene expression.

Giant intrapulmonary malignant peripheral nerve sheath tumour
Desdiani Desdiani, Siti Darifah, Chairul Azali
DOI: 10.1002/rcr2.567

We present a rare case of primary lung malignant peripheral nerve sheath tumours (MPNSTs) in an adult female non-smoker patient, in whom surgical thoracotomy approach has obtained a good control of the disease. Low-grade MPNST was established from excisional biopsy followed by immunohistochemistry.

Drainage of middle lobe vein into anomalous right lower lobe vein: management during thoracoscopic lobectomy
Dario Amore, Alessandro Saglia, Dino Casazza, Tullio Valente, Pasquale Imitazione, Carlo Curcio
DOI: 10.1002/rcr2.568

Here, we report a case of middle lobe vein draining into a right inferior lobar vein formed by two anomalous trunks lying on the superior surface of the common basal bronchus: in such instance, to avoid compromising the middle lobe vein drainage during a thoracoscopic right lower lobectomy, the two main tributaries of the lower lobe vein were individually identified and dissected peripherally from the anterior aspect after division of the major fissure. A careful hilar dissection and a precise surgical strategy can help surgeons perform correct procedures in presence of pulmonary vascular anomalies.

Autoimmune pulmonary alveolar proteinosis prior to myelodysplastic syndrome
Chuan Tai Foo, Louis Chhor, Francis Thien
DOI: 10.1002/rcr2.569

We report the first case of autoimmune pulmonary alveolar proteinosis associated with and preceding myelodysplastic syndrome.

Destroyed lung due to sustained inflammation after chemoradiotherapy followed by durvalumab
Kageaki Taima, Hisashi Tanaka, Masamichi Itoga, Yoshiko Ishioka, Akira Kurose, Sadatomo Tasaka
DOI: 10.1002/rcr2.580

This report has presented a case of destroyed lung in a patient with non-small cell lung cancer (NSCLC) who received chemoradiotherapy followed by durvalumab. Because of the sustained inflammation and abolished function of the left lung, left pneumonectomy was required. We considered that durvalumab might further accelerate the inflammatory response, which had been introduced by fungal infection, leading to uncontrollable inflammation of the lung.

Pleural cryobiopsy is useful for comprehensive cancer genetic panel testing
Satoru Ishii, Hiromu Watanabe, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama
DOI: 10.1002/rcr2.581

Here, we describe a case of an 83-year-old woman in whom insufficient pleural tissue to perform comprehensive cancer genetic panel testing was obtained with biopsy forceps, but sufficient tissue was obtained with cryobiopsy.

An extremely rare case of nivolumab-associated macroscopic duodenitis with spontaneous regression
Takatora Akizawa, Takeshi Saraya, Hiroki Takakura, Masachika Fujiwara, Haruyuki Ishii, Hajime Takizawa
DOI: 10.1002/rcr2.582

Immune-related adverse events usually occur in the colon; however, the duodenum could be affected by the immune checkpoint inhibitors. This is an extremely rare phenomenon that is characterized by pathologically non-specific inflammation.

Diffuse large B-cell lymphoma presenting with cavitary lung disease
Yukiko Hibino, Ryosuke Imai, Torahiko Jinta
DOI: 10.1002/rcr2.584

We herein report a case in which a patient with diffuse large B-cell lymphoma (DLBCL) presented with cavitary lung disease and splenic mass, which was diagnosed by transbronchial biopsy. DLBCL should be considered as a differential diagnosis in patients with cavitary lung diseases who have rare metastatic lesions for primary lung cancer, such as intra-abdominal lymph nodes or spleen.

Bronchogenic cysts mimicking thymoma in the anterior mediastinum
Jonggeun Lee, Jee Won Chang
DOI: 10.1002/rcr2.583

We present two cases of surgically resected bronchogenic cysts in the anterior mediastinum mimicking thymoma.

Pulmonary tuberculosis in an immunocompetent patient with primary laryngeal aspergillosis
Nirmal Kanti Sarkar, Bijoy Pada Gope
DOI: 10.1002/rcr2.586

A 45-year-old physician presented with dry cough and progressive vocal fatigue and was diagnosed as primary laryngeal aspergillosis. Further work-up revealed coexistent pulmonary tuberculosis.

High-pressure leakage of pleural fluid through the healed entry site of the indwelling pleural catheter from undrained locules
Ka Pang Chan, Ka Ching Joyce Ng, Chi To Kevin Li
DOI: 10.1002/rcr2.587

This is the first case report for fluid leakage through a healed entry site of the indwelling pleural catheter due to high pressure built from undrained pleural fluid locules. The condition was successfully treated with an additional drain targeting the largest undrained locule.

Sleep-related breathing disorders associated with the characteristics of underlying congenital rare diseases of Moebius syndrome and Poland syndrome
Ai Inagaki Sugiyama, Satomi Shiota, Tomoko Yamada, Jun Ito, Kazuhiro Suzuki, Kazuhisa Takahashi
DOI: 10.1002/rcr2.579

Here, we describe in detail the causal interactions between underlying two intractable and rare diseases, namely Moebius syndrome and Poland syndrome, and sleep-related breathing disorders in a 24-year-old woman.

Clinical Image
An unanticipated use of the nasogastric feeding tube
Satoru Yanagisawa, Ohe Takashi
DOI: 10.1002/rcr2.561

Nasogastric feeding (NGF) tube should be used only for the main intended purpose such as feeding, and the correct insertion of the NGF tube into the gastrointestinal tract is encouraged; however, an NGF tube aberrantly inserted into the lung might provide a valuable opportunity of obtaining samples from the lower respiratory tract. Here, we present the case of a 77-year-old-man with right lower pneumonia who required NGF. The NGF tube was inadvertently inserted into the right main airway to the lower lung and immediately removed. However, the tube had collected some sample which was used to confirm the presence of methicillin-resistant Staphylococcus aureus (MRSA) which guided treatment.

Miliary opacities in pulmonary sarcoidosis
Keishi Sugino, Hirotaka Ono, Masahiro Ando, Seiji Igarashi, Atsuko Kurosaki, Eiyasu Tsuboi
DOI: 10.1002/rcr2.563

We present a rare case of a 37-year-old woman diagnosed with pulmonary sarcoidosis who presented with unusual bilateral upper lobes miliary opacities on chest high-resolution computed tomography.

Incidental synchronous bronchial tumour: an unusual bronchoscopic finding
Umberto Caterino, Dario Amore, Chiara Petagna, Albina Palma, Danila Caroppo, Simona Massa
DOI: 10.1002/rcr2.585

We describe a patient with incidental endobronchial synchronous hamartoma and typical carcinoid and the management strategy.

Regional society news

The spotlight this month is on

BANGLADESH

Each month we share details of activities of a particular country, region or society.

If you would like the spotlight to be on your country, region or society next month, contact the Bulletin Coordinator or APSR Secretariat.

The following activities were organized by the Bangladesh Lung Foundation (BLF) in 2019, as reported by the Bangladesh Councillors:
Dr Asif Mujtaba Mahmud
Dr Hena Khatun and
Dr Ashraful Alam Khan

The Bangladesh Lung Foundation undertook many activities last year, the important ones being:

  1. New Executive Committee

    A new Executive Committee consisting of 21 members was formed in March with Prof. Md Ali Hossain as President and Dr Asif Mujtaba Mahmud as Secretary General. Dr Mohammad Abdus Shakur Khan and Dr Kazi Saifuddin Bennoor were nominated as Treasurer and Joint Secretary respectively.

    The posts of office bearers and member secretaries of cells have also been redesignated to infuse fresh blood into the organization.

  2. Health camp

    Medical checkup and health awareness campaign has been conducted among workers in leather tannery areas and underprivileged children.

  3. Technical collaboration on Genexpert screening for TB symptomatics under social business model for Public-Private Mix (PPM) in TB control

    Since this is an innovative undertaking strengthening PPM, the BLF is providing technical collaboration for the enterprise, particularly in building networks and motivating medical practitioners to optimally utilize the services at the centres. The cases have been notified to the National TB control programme. We are thereby contributing to TB control in Bangladesh, a high-burden TB country.

  4. Tobacco control activities organized by the United Forum Against Tobacco (UFAT)

    The BLF is a component society of the UFAT which is regularly organizing various activities for tobacco control.

  5. Observance of World Lung day

    In response to the FIRS and APSR President's call for observing World Lung Day in a befitting manner, the BLF organized an awareness programme on the challenges of lung health at a leading public school.

    Following a keynote presentation, a lively talk by Zahid Hossain, a charismatic showbiz icon, generated great enthusiasm among the students. He led the students in taking an oath against smoking. He pledged to serve as a goodwill ambassador for the BLF. We intend to launch an awareness campaign for promotion of lung health with him at the forefront.

Other regional news:

China

The date has changed for the World Congress of Bronchology & Interventional Pulmonology (WCBIP), biennial flagship international congress of the WABIP (World Association of Bronchology & Interventional Pulmonology).

This had been scheduled to be held in Shanghai, China, on 16-19 April 2020 and has been postponed to 24-27 September 2020 due to the coronavirus pandemic.

Please check the WABIP webpage www.wabip.com/congress for the latest details.

Japan

The date has changed for the 60th Annual Meeting of the Japanese Respiratory Society

This had been scheduled to be held in Nagoya on 24-26 April 2020 and has been postponed to 20-22 September 2020 due to the coronavirus pandemic. The venue has also been changed and the Annual Meeting will now be held at the Kobe Convention Center, Japan.

Please check the JRS webpage www.jrs.or.jp/jrs60/en/index.html for the latest details.

Singapore

The Singapore Thoracic Society's Singhealth Interstitial Lung Disease Workshop will be held on 11 July 2020.

In view of the COVID-19 pandemic, this will be delivered online as a web-based workshop.

Please check the STS website www.thoracic.sg for the latest details.

Also due to the pandemic, the date of the World Conference on Lung Cancer has changed.

This had been scheduled to be held on 9-12 August 2020 and has been postponed to 26-29 January 2021.

Please check the IASLC website wclc2020.iaslc.org for the latest details.

Other health news

World No Tobacco Day
31 May 2020

Press release:

Tokyo, 31 May – Respiratory groups call for stronger measures to protect young people from tobacco industry marketing On World No Tobacco Day, 31 May 2020, the Forum of International Respiratory Societies (FIRS), of which the APSR is a founding member, calls on governments and policymakers to implement stronger measures to protect teenagers and adolescents from tobacco industry marketing, in order to safeguard health and to support global public health goals for a tobacco-free generation.

The call is issued in support of the World Health Organization's (WHO) overarching World No Tobacco Day (WNTD) 2020 theme, which focuses on exposing the strategies used by the tobacco industry to appeal to young people in its marketing of novel tobacco and nicotine products such as e-cigarettes, heated tobacco and "smokeless" tobacco products.

In its WNTD 2020 launch statement, the WHO outlines the key strategies used by the tobacco industry to entice young people to use novel tobacco and nicotine products, including through the use of sweet flavourings, false claims about the "safety" of novel tobacco products, indirect marketing on TV, film and online through social media influencers, and by using "sleek" product designs to hide the fact its products are devices of tobacco and nicotine inhalation.

Many studies have found that e-cigarette vapour contains toxic and cancer-causing chemicals, and almost all independent research has revealed some negative health effects associated with e-cigarette use. Existing evidence indicates that this damage will have lasting effects and may lead to the development of diseases in later life [1].

Further, there is currently no evidence to show that heated or "smokeless" tobacco products are less harmful than traditional cigarettes to health. Previous research has shown that more than 20 harmful chemicals were found in heat-not-burn products in higher amounts than in traditional cigarette smoke, and there is some evidence that new chemicals exist in heat-not-burn products that are not present in traditional cigarettes, which could be toxic to the health of young people [1].

FIRS believe that governments have an important role to play in the implementation of legislation to limit these strategies and strongly supports the WHO's recommendations on ways to counter the tobacco industry, including by:

  • Supporting the implementation of comprehensive tobacco control policies, such as those outlined in the WHO Framework Convention on Tobacco Control.
  • If not banning, then by applying strict regulations on the sale of electronic nicotine delivery systems (ENDS) and electronic non-nicotine delivery systems (ENNDS).
  • Implementing bans on advertising, promotion and sponsorship of nicotine and tobacco products.
  • Enforcing policies to prevent tobacco industry lobbying and interference in tobacco control policies.
  • Supporting youth groups to advocate, engage and educate young people to help build a movement for a tobacco-free generation.
  • Instructing schools to raise awareness of the dangers of initiating nicotine and tobacco product use and adopt tobacco and e-cigarette free campuses.

We must stop the tobacco industry targeting a new generation. FIRS encourages the public health community, civil society organisations, governments, the media and the public, to support World No Tobacco Day 2020 and to get involved in WHO activities for this important awareness event.

[1] breathe.ersjournals.com/content/16/1/161ELF.article-info

About the Forum of International Respiratory Societies

The Forum of International Respiratory Societies (FIRS) is an organization comprising the world's leading international respiratory societies working together to improve lung health globally: American College of Chest Physicians (CHEST), American Thoracic Society (ATS), Asian Pacific Society of Respirology (APSR), Asociación Latino Americana de Tórax (ALAT), European Respiratory Society (ERS), Global Initiative for Asthma (GINA), Global Initiative for Chronic Obstructive Lung Disease (GOLD), International Union Against Tuberculosis and Lung Diseases (The Union), and the Pan African Thoracic Society (PATS).

The goal of FIRS is to unify and enhance efforts to improve lung health through the combined work of its more than 70,000 members globally.

Contact: Lisa Roscoe, lisa.roscoe@firsnet.org

Education

Teaching Library

The Teaching Library is open for your self-study. Challenging yourself to choose the correct procedure for any of the 91 cases in the Library at apsresp.org/education/teaching-library/index.php.

Many more cases are needed for this Library and any member is welcome to submit a case through the same link as above.

New educational article

The following article has recently been selected from Respirology for its specific educational value. Previous articles on further topics can be seen at apsresp.org/education/articles/index.html


Figure 1 of 10.1111/resp.13696
(Click image to enlarge)

Of special interest to those working in:
* Environmental & Occupational Health
* Cell and Molecular Biology
* Clinical Respiratory Medicine

Effects of E-cigarette E-liquid components on bronchial epithelial cells: Demonstration of dysfunctional efferocytosis Miranda P Ween, Rhys Hamon, Matthew G MacOwan, Leigh Thredgold, Paul R Reynolds and Sandra J Hodge (DOI: 10.1111/resp.13696)
onlinelibrary.wiley.com/doi/10.1111/resp.13696/full (May 2020)

Comment by Dr Mark Lavercombe:
While the cause of the outbreak of e-cigarette, or vaping, product use associated lung injury (EVALI) in the United States remains under investigation, the broader issue of the long-term safety of vaping remains contentious. This paper contributes to the literature demonstrating abnormalities of human bronchial epithelial cell function associated with e-cigarette use. Further investigation and long-term data will be required.

APSR Membership

New and updated assembly memberships

A warm welcome to the following members who have recently joined or re-joined APSR assemblies.

Erwin Arief Clinical Allergy & Immunology
Critical Care Medicine
Lung Cancer
Chuling Fang Interstitial Lung Disease
Abdulrahman Hakami Clinical Respiratory Medicine
Tuberculosis
Paediatric Lung Disease
Arun Chowdary Kotaru Bronchoscopy and Interventional Techniques
Pulmonary Circulation
Lung Cancer
Chin Tong Kwok COPD
Tuberculosis
Lung Cancer
Saurabh Mittal Bronchoscopy and Interventional Techniques
Respiratory Neurobiology and Sleep
Critical Care Medicine
Vorakamol Phoophiboon Critical Care Medicine
Clinical Respiratory Medicine
Pulmonary Circulation
D Sachin Clinical Respiratory Medicine
Bronchoscopy and Interventional Techniques
Critical Care Medicine
Nirmal Kanti Sarkar Clinical Respiratory Medicine
Tuberculosis
Bronchoscopy and Interventional Techniques
Ika Trisnawati Lung Cancer
Respiratory Infections (non-tuberculous)
Bronchoscopy and Interventional Techniques
Ye Tun Clinical Respiratory Medicine
Respiratory Infections (non-tuberculous)
COPD
Peet Viviers Clinical Respiratory Medicine
Interstitial Lung Disease
Critical Care Medicine

Future Pulmonology Events

Here are the main respiratory events in Asia-Pacific region for the next few months. You can see our full listing on the APSR Calendar.

  • Malaysian Thoracic Society (MTS) 2020 Annual Congress
    16-19 Jul 2020 Postponed to 10-13 December 2020, Nusajaya, Johor, Malaysia
    (Details)
  • Respire 12 Annual Academic Sessions of Sri Lanka College of Pulmonologists (SLCP)
    20-22 July 2020 New date will be announced when confirmed, Kandy, Sri Lanka
    (Details)
  • Annual Scientific Congress of Ho Chi Minh City Society of Asthma, Allergy & Clinical Immunology
    26 July 2020, Ho Chi Minh City, Vietnam
    (Details)
  • 60th Annual Meeting of the Japanese Respiratory Society
    20-22 September 2020, Kobe Convention Center, Japan
    (Details)
  • World Congress of Bronchology & Interventional Pulmonology (WCBIP)
    24-27 September 2020, Shanghai, China
    (Details)
  • The 16th National Congress Indonesian Society of Respirology in conjunction with 1st Indonesia Chronic Lung Disease International Meeting (ICLIME)
    23-26 September 2020, Makassar, Indonesia
    (Details)
  • Scientific conference with updates from The Congress of European Respiratory Society (ERS) 2020 (VNRS)
    25-26 September 2020, Hanoi, Vietnam
    (Details)

For more pulmonology events, see apsresp.org/calendar.html
(These events are for information only and APSR endorsement should not be assumed.)

Contact

If you have news of interest to APSR members, please send details to one of the Bulletin Coordinators; Prof. A Azuma (a-azuma@nms.ac.jp) or Prof. C K Rhee (chinkook77@gmail.com).


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