APSR Respiratory Updates
Dr David CL Lam
APSR Respiratory Updates is a unique publication bringing you the most important clinical research in respiratory medicine. Each month an expert within the APSR will identify and review ten key publications in their field. In addition to a link to the publication, a brief commentary on why the study is important will be provided. This series represents an important initiative of the Education Committee of the APSR. We hope you find it informative and useful in your clinical practice.
Dr David CL Lam
|Volume 5, Issue 5
- Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998-2008.
- Rescue therapy by switching to total face mask after failure of face mask-delivered noninvasive ventilation in Do-Not-Intubate patients in acute respiratory failure
- Noninvasive ventilation in acute hypercapnic respiratory failure caused by obesity hypoventilation syndrome and chronic obstructive pulmonary disease.
- Optimization of ventilator setting by flow and pressure waveforms analysis during noninvasive ventilation for acute exacerbations of COPD: a multicentric randomized controlled trial
- Polysomnography in stable COPD under non-invasive ventilation to reduce patient-ventilator asynchrony and morning breathlessness
- High pressure versus high intensity noninvasive ventilation in stable hypercapnic chronic obstructive pulmonary disease: a randomized crossover trial
- Physiological changes during low- and high-intensity noninvasive ventilation.
- Noninvasive ventilation in mild obesity hypoventilation syndrome: a randomized controlled trial.
- Impact of different back-up respiratory rates on the efficacy of non-invasive positive pressure ventilation in obesity hypoventilation syndrome: a randomized trial
- Volume targeted versus pressure support non-invasive ventilation in patients with super obesity and chronic respiratory failure: a randomised controlled trial
|Volume 5, Issue 4
Monitoring free serum IgE in severe asthma patients treated with omalizumab
- Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma.
- Effects of adding omalizumab, an anti-immunoglobulin E antibody, on airway wall thickening in asthma.
- A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.
- Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered
- Soluble CD23 controls IgE synthesis and homeostasis in human B cells.
- Microarray evaluation of specific IgE to allergen components in elite athletes.
- Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma.
- Population-based study of multiplexed IgE sensitization in relation to asthma, exhaled nitric oxide, and
- High-dose sublingual immunotherapy with single-dose aqueous grass pollen extract in children is effective
and safe: a double-blind, placebo-controlled study.
|Volume 5, Issue 3
Lung Cancer Screening
- Annual number of lung cancer deaths potentially avertable by screening in the United States
- Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: a cohort study
- Predictive accuracy of the Liverpool Lung Project risk model for stratifying patients for computed tomography screening for lung cancer
- Two microRNA panels to discriminate three subtypes of lung carcinoma in bronchial brushing specimens
- Non-invasive breath analysis of pulmonary nodules
- Biomarkers to help guide management of patients with pulmonary nodules
- Definition of a positive test result in computed tomography screening for lung cancer
- Selection criteria for lung-cancer screening
- Using socio-demographic and early clinical features in general practice to identify people with lung cancer earlier
- Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial
|Volume 5, Issue 2
- Multidrug-resistant pulmonary tuberculosis treatment regimens and patient outcomes:
an individual patient data meta-analysis of 9,153 patients.
- Risk of progression to active tuberculosis following reinfection with Mycobacterium tuberculosis.
- Identifying predictors of interferon-γ release assay results in pediatric latent tuberculosis: a protective role of Bacillus Calmette-Guérin A pTB-NET collaborative study.
- Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.
- Surgical face masks worn by patients with multidrug-resistant tuberculosis. Impact on infectivity of air on a hospital ward.
- 14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trial.
- Delamanid for multidrug-resistant pulmonary tuberculosis.
- The immune reconstitution inflammatory syndrome after antiretroviral therapy initiation in patients with tuberculosis: findings from the SAPiT trial.
- Fluorescein diacetate vital staining allows earlier diagnosis of rifampicin-resistant tuberculosis.
- Predictive value of interferon-g release assays for incident active tuberculosis: a systematic review and meta-analysis.
|Volume 5, Issue 1
Current Trends in Lung Cancer Surgery
- Oncologic efficacy of anatomic segmentectomy in stage IA lung cancer patients with T1a tumors
- Is limited pulmonary resection equivalent to lobectomy for surgical management of stage I non-small-cell lung cancer?
- Point/Counterpoint: are limited resections appropriate in non-small cell lung cancer? Yes/No
- Morphological analysis of circulating tumour cells in patients undergoing surgery for non-small cell lung carcinoma using the isolation by size of epithelial tumour cell (ISET) method
- Recurrence dynamics for non-small-cell lung cancer: effect of surgery on the development of metastases
- Patterns of recurrence and incidence of second primary tumors after lobectomy by means of videoassisted thoracoscopic surgery (VATS) versus thoracotomy for lung cancer
- Lung cancer screening and video-assisted thoracic surgery
- Surgical resection of highly suspicious pulmonary nodules without a tissue diagnosis
- Operating on a suspicious lung mass without a preoperative tissue diagnosis: pros and cons
- Improved outcomes associated with higher surgery rates for older patients with early stage non-small cell lung cancer
- Is it safe to include octogenarians at the start of a video-assisted thoracic surgery lobectomy program?
- Lobectomy in octogenarians with non-small cell lung cancer: ramifications of increasing life expectancy and the benefits of minimally invasive surgery
|Earlier 'Respiratory Updates':|
|Earlier 'Respiratory Research Reviews':|
Disclaimer: The above publications are not intended as a replacement for regular medical education. The comments are an interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.
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