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APSR Respiratory Research Review


Lutz Beckert

This is a unique publication providing topical, relevant and accessible information for healthcare professionals working in the area. In each edition our independent reviewers handpick some of the most important studies from key international and local journals. The Review summarises each study in an easy to read format, and provides commentary on the importance of the work and implications for clinical practice in the Asia-Pacific region. Web links to the abstract or fully published papers are also provided where possible so you can make your own judgements.

We hope you enjoy the latest edition and you are welcome to email comments to the Editor, Dr Lutz Beckert - lutzbeckert@researchreview.co.nz

Respiratory Updates (archives)
2017 (current)
2016 Archive
  • Pulmonary rehabilitation in COPD
  • Lung Development and Regeneration
  • Lymphangioleiomyomatosis
  • Obesity Hypoventilation Syndrome
  • Update in Acute Respiratory Distress Syndrome
  • Lung Transplantation
  • Lung cancer immunotherapy
  • Pneumonia
  • Updates in Pulmonary Function Testing 2012-2015
  • Pulmonary Aspergillosis
  • Updates on Bronchoscopy and Interventional Pulmonology
2015 Archive
  • Cystic Fibrosis (CF)
  • Tobacco/Smoking Cessation
  • Pulmonary Circulation
  • Idiopathic Pulmonary Fibrosis trials and Sarcoidosis
  • Mesothelioma
  • Bronchiectasis
  • APSR air pollution update
  • Induced Sputum 2015
  • Pneumothorax: Evolving Indications for Surgery
  • Non-invasive ventilation
  • Cellular and molecular biology of the lung
  • Quantitative Imaging of the Respiratory System
2014 Archive
  • COPD
  • Tuberculosis
  • Environmental and Occupational Health
  • APSR Paediatric Updates 2014
  • Pneumoconiosis and other related conditions
  • Sleep Medicine
  • Critical Care Medicine
  • Interstitial Lung Diseases
  • Pleural Diseases
  • Asthma
  • Lung Cancer
  • Venous Thromboembolism
2013 Archive
  • Fukuchi Award and Young Investigator Award Abstracts
  • Mesothelioma
  • Cystic Fibrosis and Bronchiectasis
  • Lung transplantation
  • Air Pollution
  • Induced sputum
  • Respirology Virtual Issues
  • Non-invasive ventilation
  • Monitoring free serum IgE in severe asthma patients treated with omalizumab
  • Lung Cancer Screening
  • Tuberculosis
  • Current Trends in Lung Cancer Surgery
2012 Archive
  • Progress of Pulmonary Function Testing in 2011/12
  • IPF trials and Sarcoidosis
  • Respiratory infections other than tuberculosis
  • Cell and Molecular Biology in Respirology
  • Pulmonary Circulation
  • Quantitative imaging of airways
  • Paediatric lung disease
  • Tuberculosis
  • Community and Public Health
  • Chronic obstructive pulmonary disease (COPD)
  • Epithelial-mesenchymal transition (EMT) in lung disease
  • Tobacco/Smoking cessation
2011 Archive
  • Pneumoconiosis
  • Environmental & Occupational Health
  • Bronchoscopy & Interventional Techniques
  • Sleep
  • Critical Care Medicine
  • Influenza
  • Interstitial Lung Diseases
  • Pleural Diseases
  • Asthma
  • Lung Cancer
  • Pulmonary and Systemic Venous Thromboembolism
2010 Archive
  • Community and Public Health
  • Tuberculosis
  • Tobacco/smoking cessation
  • Paediatric lung disease
  • Sleep
  • Pneumonia
  • Bronchoscopy & Interventional Techniques
  • Pleural diseases
  • Asthma
  • Critical Care Medicine
  • Interstitial Lung Disease
  • COPD & asthma: Differences & similarities
2009 Archive
  • Influenza
  • Lung Cancer
  • Venous Thromboembolism
Respiratory Research ReviewContents
Issue 27 (2008)
  • LLN of FEV1/FVC ratio reduces airway obstruction misclassification
  • FEV1/FVC <70% underestimates airflow obstruction
  • Driving performance not improved by O2 therapy in hypoxaemia
  • Modified BODE: validation with mortality in COPD
  • 6MWD as a predictor of mortality in stable COPD
  • Language differentiates between adults with and without COPD
  • A cell phone-based exercise programme for COPD
  • SaO2 during sex in COPD
  • Medications for recently diagnosed COPD and risk for death
  • Long-term erythromycin decreases COPD exacerbations
  • β-blockers and mortality in COPD patients with atherosclerosis
  • P. aeruginosa transmission: infrequent in NZ CF clinics
Issue 26 (2008)
  • Paracetamol use and asthma
  • Risks with paracetamol use in infancy/childhood
  • Home heating and asthma in children
  • Asthma self-management education: nurses vs. lay people
  • Alcohol levels with hydrofluoroalkane-ethanol inhalers
  • The burden of chronic cough for families
  • Improved O2 systems for childhood pneumonia
  • Indirect effect of 7-valent PCV on unvaccinated household members
  • PPIs and risk of CAP
  • Statin use and pneumonia outcomes
Issue 25 (2008)
  • RV contractility in SSc- and idiopathic PAH
  • HRCT in symptomatic scleroderma-related interstitial lung disease
  • Clinical PAH outcomes with BMPR2 mutation
  • Long-term sildenafil in inoperable CTEPH
  • Treating mildly symptomatic PAH with bosentan
  • Bosentan in severe COPD: an RCT
  • Bosentan in PAH: the relationship between 6MWD and QOL
  • Improved outcomes In CTEPH
  • H-FABP for assessing risk in CTEPH
  • Survival and prognosis in PoPH
Issue 24 (2008)
  • CPAP vs. BVS in obesity hypoventilation syndrome
  • Effect of CPAP on vascular function in OSAHS
  • 'Tennis ball technique' vs. nCPAP in position-dependent OSA
  • Acylated ghrelin levels before and after nasal CPAP
  • Motor vehicle crashes in patients with OSA/H
  • Persistence of OSA after surgical weight loss
  • Sleep-disordered breathing and postoperative complications
  • Health belief model predicts adherence to CPAP
  • Comparison of oral appliances for mild sleep apnoea
  • A titration strategy for oral appliances prescriptions for OSA
Issue 23 (2008)
  • Varenicline vs. NRT for smoking cessation
  • Salmeterol/fluticasone propionate plus tiotropium bromide
  • Tiotropium with placebo, salmeterol or salmeterol + fluticasone
  • Tiotropium plus formoterol vs. salmeterol plus fluticasone
  • Magnesium: a predictor of frequent COPD readmissions
  • Short-course antibiotics in exacerbations of chronic bronchitis and COPD
  • Exertional dyspnoea in obese women: an increased O2 cost of breathing
  • Azithromycin: effects on phagocytosis and mannose receptors
  • Panic attacks and inspiratory resistive load perception
  • Carbocisteine in COPD acute
Issue 22 (2008)
  • Preschool children with wheeze: long-term prognosis
  • Aspirin and risk of adult-onset asthma in women
  • Effect of dietary antioxidants on asthma
  • Predictors for wheezing phenotypes during first decade of life
  • Treatment adherence in young children with asthma
  • Effect of obesity on respiratory function in female asthmatics
  • Longitudinal study of airway function in ex-preterms
  • Clinical outcomes of PAH in BMPR2 mutation carriers
  • Pulmonary manifestations in POEMS syndrome
  • d-MPH for sarcoidosisassociated fatigue
Issue 21 (2008)
  • Diagnosing pulmonary MAC with enzyme immunoassay
  • Antituberculosis drug resistance in the UK
  • Predictive value of IFN-γ assay in recent TB infection
  • IFN-γ release assay to diagnose latent TB infection
  • QuantiFERON TB-2G test in elderly TB patients
  • Model for efficient screening of TB contacts
  • Nortriptyline plus NRT in smoking cessation
  • Safety of LABAs in stable COPD
  • Pneumonia in elderly patients with COPD
  • Diagnosing PE by multidetector CT +/- venous ultrasound
Issue 20 (2008)
  • Time to antibiotics and pneumonia diagnosis
  • Chest x-ray and time to antibiotics in pneumonia
  • PPV and CAP outcomes
  • Thin-section CT and lung tumour prognosis
  • Hypoxia test cut-offs in neonatal CLD
  • Hypoxia tests to predict in-flight hypoxaemia
  • HCT for predicting in-flight hypoxia in preterms
  • Extrapulmonary COPD effects and physical activity
  • Dust mite control in asthma
  • Chronic community beryllium exposure
  • LB and lung transplant outcomes
Issue 19 (2008)
  • Dyspnoea and airway responses in obesity
  • Single versus bilateral lung transplantation
  • Cotton dust exposure and lung function
  • Wood dust effects on lung function
  • Variations in COPD exacerbation analyses
  • Snoring and chronic bronchitis
  • Effect of macrolides on airway hypersecretion
  • β-blocker use for CV disease in COPD
  • FEV6 and FVC for predicting lung capacity
  • rhDNase for acute asthma in children
Issue 18 (2008)
  • VTE risk in acute hospitalisation
  • VTE risk with minor injuries
  • Assessing LV/RV ratio in PE
  • Concomitant coumarins and SSRIs
  • Outcomes following DVT and PE
  • Thrombocytopenia with heparin: incidence and impact
  • TE risk with warfarin interruptions
  • Cannabis and lung cancer risk
  • Cannabis and bullous lung disease
  • Lung clearance index in CF
Issue 17 (2008)
  • Young people, money & access to tobacco
  • ICU outcome & prognosis for lung cancer patients
  • Spirometry in general practice
  • Management of primary spontaneous pneumothorax
  • Nasal surgery in OSA
  • Auto-CPAP versus fixed-CPAP in OSA
  • Chronic sleep restriction & daytime sleepiness
  • Salmeterol/fluticasone vs tiotropium for COPD exacerbations
  • Bosentan for idiopathic pulmonary fibrosis
  • Cyclophosphamide in scleroderma interstitial lung disease
Issue 16 (2008)
  • Lung disease and safety of air travel
  • Diagnosis of PE in hospitalised patients
  • CTPA vs VQ for suspected PE
  • Fatal PE risk after cessationof VTE anticoagulant therapy
  • ADRB2 polymorphisms and response to long-acting ß2-agonists
  • Flexible bronchoscopy in patients with chronic cough
  • Second-hand smoke and quality of life
  • Hospitalisation rates for COPD in Australia
  • Predictors of hospital admission for COPD
  • Range and severity of COPD symptoms in older adults
Respiratory Research Review (archives)
2007 Archive
2006 Archive

Disclaimer: The APSR Respiratory Research Review is not intended as a replacement for regular medical education but to assist in the process. The reviews are a summarised interpretation of the published study and reflect the opinion of the writer rather than those of the research group or scientific journal. It is suggested readers review the full trial data before forming a final conclusion on its merits.

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