A selection of publications with educational value in
Bronchoscopy and Interventional Techniques
Most recently added articles listed first
- Predictors of longitudinal changes in body weight, muscle and fat in patients with and ever-smokers at risk of COPD
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Akio Yamazaki, Daisuke Kinose, Satoru Kawashima, Yoko Tsunoda, Yumiko Matsuo, Yasuki Uchida, Hiroaki Nakagawa, Masafumi Yamaguchi, Emiko Ogawa, Yasutaka Nakano (DOI: 10.1111/resp.14537)
onlinelibrary.wiley.com/doi/10.1111/resp.14537/full (September 2023)Comment by Dr Mark Lavercombe:
It is known that having Chronic Obstructive Pulmonary Disease results in increased energy expenditure, and that both weight loss and muscle loss are associated with poorer outcomes. In this study, the authors assessed annual body composition changes using computed tomography in a cohort of patients with COPD or at risk for COPD. Participants experienced an annual loss of weight and height, with no change in their body mass index, while decreased muscle mass and increased fat mass were noted over time. Muscle loss was most obvious in those with reduced lung function.20230719 - Ipsilateral and contralateral hemidiaphragm dynamics in symptomatic pleural effusion: The 2nd PLeural Effusion And Symptom Evaluation (PLEASE-2) Study Deirdre B Fitzgerald, Sanjeevan Muruganandan, Carolyn J Peddle-McIntyre, Y C Gary Lee and Bhajan Singh (DOI: 10.1111/resp.14307)
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onlinelibrary.wiley.com/doi/10.1111/resp.14307/full (June 2022)Comment by Dr Mark Lavercombe:
This fascinating paper reports the result of bedside ultrasonographic evaluation of both ipsilateral and contralateral diaphragmatic function in patients presenting with unilateral pleural effusion, before and after pleurocentesis. Contralateral hemidiaphragmatic excursion increased in inverse proportion to ipsilateral hemidiaphragmatic excursion, with subsequent normalisation on both sides after drainage. Improvement in ipsilateral excursion correlated with improvement in dyspnoea. These novel findings suggest the need for further study of ventilatory drive and the mechanics of both hemidiaphragms in the setting of pleural effusion, and their association with dyspnoea.20220912 - A comprehensible machine learning tool to differentially diagnose idiopathic pulmonary fibrosis from other chronic interstitial lung diseases Taiki Furukawa, Shintaro Oyama, Hideo Yokota, Yasuhiro Kondoh, Kensuke Kataoka, Takeshi Johkoh, Junya Fukuoka, Naozumi Hashimoto, Koji Sakamoto, Yoshimune Shiratori, Yoshinori Hasegawa (DOI: 10.1111/resp.14310)
(Figure 1 of 10.1111/resp.14310)
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onlinelibrary.wiley.com/doi/10.1111/resp.14310/full (September 2022)Comment by Dr Mark Lavercombe:
Using their cohort of 1068 consecutive patients with chronic interstitial lung diseases (ILD), the authors of this paper designed a two-step machine learning algorithm for the diagnosis of idiopathic pulmonary fibrosis (IPF) based on patient characteristics, imaging findings, blood tests and pulmonary function tests. Their algorithm can diagnose and differentiate IPF from other ILDs with similar accuracy to multi-disciplinary team (MDT) discussion. Further, patients with IPF diagnosed by artificial intelligence had a poorer prognosis even than those diagnosed with IPF at MDT. Validation on other cohorts is needed to confirm generalisability.20220809 
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(Click image to enlarge)One-year Follow-up CT Findings in COVID-19 Patients: A Systematic Review and Meta-analysis Atsuyuki Watanabe, Matsuo So, Masao Iwagami, Koichi Fukunaga, Hisato Takagi, Hiroki Kabata, Toshiki Kuno (DOI: 10.1111/resp.14311)
onlinelibrary.wiley.com/doi/10.1111/resp.14311/full (August 2022)Comment by Dr Mark Lavercombe:
In this systematic review and meta-analysis, the authors examine the imaging and pulmonary function sequelae of COVID-19 infection at twelve months. In the 15 articles included, residual abnormalities on chest CT at twelve months were present in approximately one third of patients. The most common findings were ground glass opacity, fibrotic-like changes and bronchiectasis. Residual abnormalities were more common in patients classified as having had severe/critical COVID-19 infection. The most common abnormality at pulmonary function testing was reduced DLCO in around 30% of patients, again more frequently in those who had had severe/critical COVID-19 infection. Given the enormous burden of the COVID-19 pandemic, longitudinal follow-up data like these are critical to inform clinical practice and service planning.20220622- Impact of Structured Curriculum with Simulation on Bronchoscopy Wen Ting Siow, Gan‐Liang Tan, Chian‐Min Loo, Kay‐Leong Khoo, Adrian Kee, Augustine Tee, Imran bin Mohamed Noor, Noel Tay, Pyng Lee (DOI: 10.1111/resp.14054)
Figure 1 of 10.1111/resp.14054
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onlinelibrary.wiley.com/doi/10.1111/resp.14054/full (Jun 2021)Comment by Dr Mark Lavercombe:
The issues of procedural training and assessment of competence are subject to significant debate with a variety of approaches described. In this paper, the authors demonstrate a significant difference in performance measured using the Bronchoscopy Skills and Tasks Assessment Tool (BSTAT) and several other measures, after a 3-month structured curriculum including weekly simulation and direct supervision. Further work is needed to demonstrate a link to diagnostic yield and patient complications.20180521 - Year in review 2017: Interventional pulmonology, lung cancer, pleural disease and respiratory infections Lonny Yarmus, Phan T Nguyen, Kristina Montemayor, Mark Jennings, Brett Bade, Majid Shafiq, Gerard Silvestri, Daniel Steinfort
onlinelibrary.wiley.com/doi/10.1111/resp.13306 (Apr 2018)20180430 - Diagnostic utility of surgical lung biopsies in elderly patients with indeterminate interstitial lung disease Laszlo T Vaszar, Brandon T Larsen, Karen L Swanson, Jay H Ryu, Henry D Tazelaar (DOI: 10.1111/resp.13223)
Table 3
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onlinelibrary.wiley.com/doi/full/10.1111/resp.13223 (Apr 2018)Comment by Dr Mark Lavercombe:
Surgical lung biopsy for pathological correlation with the clinico-radiologic diagnosis in idiopathic interstitial pneumonia is associated with a risk of morbidity and mortality. These risks increase with age. In this retrospective cohort of elderly patients (≥75y), the authors demonstrate that biopsy features were not those of UIP in 39% of cases where HRCT was inconsistent with UIP. This diagnostic benefit is countered by significant 30- and 90-day mortality.20180420 - Usefulness of a routine endoscopic assessment of laryngeal lesions after lung cancer surgery Alex Fourdrain, Florence De Dominicis, Jules Iquille, Sophie Lafitte, Geoni Merlusca, Alejandro Witte Pfister, Patrick Bagan and Pascal Berna (DOI: 10.1111/resp.13139)
Table 3
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onlinelibrary.wiley.com/doi/10.1111/resp.13139/full (Jan 2018)Comment by Dr Mark Lavercombe:
Vocal cord dysfunction is not uncommon in patients after lung cancer resection, and this study demonstrates a significant association with poor post-operative outcomes including pneumonia, need for bronchoscopy and re-intubation. The authors recommend routine laryngeal screening within 24h of surgery, although treatment outcomes were not assessed in this study.20171208 - Natural history and clinical characteristics of multiple pulmonary nodules with ground glass opacity: Yuki Sato, DaichI Fujimoto, Takeshi Morimoto, Keiichiro Uehara, Kazuma Nagata, Ichiro Sakanoue, Hiroshi Hamakawa, Yutaka Takahashi, Yukihiro Imai and Keisuke Tomii (DOI: 10.1111/resp.13089)
Table 3
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onlinelibrary.wiley.com/doi/10.1111/resp.13089/full (Nov 2017)Comment by Dr Mark Lavercombe:
The authors of this paper describe the natural history of single and multiple ground glass nodules (GGN) over a 36 month period. They demonstrate that partly solid and ≥ 10mm size solitary GGN are more likely to progress, while ≥ 10 mm and past history of lung cancer were associated with progression in multiple GGN.20171027 - Endobronchial ultrasound-guided transbronchial needle aspiration: Safe as it sounds: Preyas J Vaidya, Mohammed Munavvar, Joerg D Leuppi, Atul C Mehta & Prashant N Chhajed. (DOI: 10.1111/resp.13094)
Table 5
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onlinelibrary.wiley.com/doi/10.1111/resp.13094/full (Aug 2017)Comment by Dr Mark Lavercombe:
EBUS-TBNA has rapidly become the standard of care for mediastinal and hilar lymph node sampling. This systematic review outlines the range and frequency of potential complications, as well as the possibility that these reports do not represent the full scale of adverse outcomes.20170820 - Diagnostic value of endobronchial ultrasound elastography for the differentiation of benign and malignant intrathoracic lymph nodes Potjanee Korrungruang and Viboon Boonsarngsuk (resp. 12832/ RES-15-983.R2)
Qualitative endobronchial ultrasound (EBUS) elastography classification of lymph nodes according to the dominant elastographic colour pattern (Figure 1)
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onlinelibrary.wiley.com/doi/10.1111/resp.12979/full (Jul 2017)Comment by Dr Mark Lavercombe:
The authors of this paper outline the use of EBUS elastography for both qualitative and quantitative assessment of mediastinal lymphadenopathy for the presence of malignancy. Their promising findings suggest the need for further study to better define the elastographic features in both benign and malignant conditions, in order to guide the need for TBNA sampling.20170608 - Prevalence and outcomes of diaphragmatic dysfunction assessed by ultrasound technology during acute exacerbation of COPD: A pilot study Federico Antenora, Riccardo Fantini, Andrea Iattoni, Ivana Castaniere, Antonia Sdanganelli, Francesco Livrieri, Roberto Tonelli, Stefano Zona, Marco Monelli, Enrico M Clini & Alessandro Marchioni DOI: 10.1111/resp.12916
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onlinelibrary.wiley.com/doi/10.1111/resp.12916/full (Feb 2017)Comment by Dr Mark Lavercombe:
The indications for thoracic ultrasonography continue to expand, and this study suggests another indication. Diaphragmatic dysfunction found on ultrasound on admission in patients with acute hypercapnic exacerbations of COPD is identified as a risk factor for failure of NIV, duration of mechanical ventilation and short-term mortality. This non-invasive test might help clinicians identify patients at risk of failing standard care.20170131 - Bronchoscopy assessment of acute respiratory failure in interstitial lung disease Antonella Arcadu & Teng Moua DOI: 10.1111/resp.12909
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onlinelibrary.wiley.com/doi/10.1111/resp.12909/full (Feb 2017)Comment by Dr Mark Lavercombe:
This study examines the utility of bronchoscopy in patients admitted with acute exacerbations of interstitial lung disease. Although a relatively low diagnostic yield is identified, significant potential complications are noted and there is no in-hospital mortality benefit seen in those undergoing the procedure.20170131 - Airway stenting in the management of iatrogenic tracheal injuries: 10-Year experience Tazi-Mezalek et al. DOI: 10.1111/resp.12853
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onlinelibrary.wiley.com/doi/10.1111/resp.12853/full (Jul 2016)Comment by Dr Mark Lavercombe:
This paper describes the experience of managing a very rare complication of endotracheal intubation or tracheostomy, including the nature and anatomical distribution of the injuries. Finally, outcomes using different treatment approaches is discussed.20161021
